Eosinophil Peroxidase Proteine (EPX)

EPX is a member of the peroxidase gene family and is expressed in eosinophils. Zusätzlich bieten wir Ihnen EPX Antikörper (71) und EPX Kits (26) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
EPX 8288 P11678
EPX 13861 P49290
Ratte EPX EPX 303414  
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Top EPX Proteine auf antikoerper-online.de

Showing 7 out of 12 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$4,331.68
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$7,759.50
Details
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$4,331.68
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$7,759.50
Details
Human Human Unkonjugiert 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$755.00
Details
Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 11 bis 12 Tage
$333.33
Details
Human Human Unkonjugiert Gel Scan of Eosinophil Peroxidase, Human Eosinophils (EPO)  This information is representative of the product ART prepares, but is not lot specific. 100 μg Anmelden zum Anzeigen 3 bis 4 Tage
$534.72
Details

EPX Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
,
Mouse (Murine) ,

Weitere Proteine zu Eosinophil Peroxidase (EPX) Interaktionspartnern

Xenopus laevis Eosinophil Peroxidase (EPX) Interaktionspartner

  1. tyrosine phosphorylation of PMR1 (zeige ATP2C1 Proteine) is required for the targeting and degradation of polyribosome-bound substrate mRNA

Human Eosinophil Peroxidase (EPX) Interaktionspartner

  1. peroxidase enzymes, like MPO (zeige MPO Proteine) and EPO (zeige EPO Proteine), may play a fundamental role in inhibiting RANKL (zeige TNFSF11 Proteine)-induced osteoclast differentiation at inflammatory sites of bone fracture and injury.

  2. Both MPO (zeige MPO Proteine) and EPO (zeige EPO Proteine) are causatively involved in breast cancer progression and identified as potential therapeutic targets whereby specific novel inhibitors may reduce tumor growth and limit the occurrence of metastasis.

  3. The main significance of this work is the discovery of EPO (zeige EPO Proteine) as a novel ligand for the HER2 (zeige ERBB2 Proteine) receptor. Following HER2 (zeige ERBB2 Proteine) activation, EPO (zeige EPO Proteine) induces activation of FAK (zeige PTK2 Proteine) and subsequent activation of beta1-integrin, via inside-out signaling. This complex results in downstream activation of ERK1/2 and a sustained up regulation of both MUC4 (zeige MUC4 Proteine) and the HER2 (zeige ERBB2 Proteine) receptor

  4. EPO (zeige EPO Proteine)-mediated protein carbamylation is promoted during allergen-induced asthma exacerbation, and can both modulate immune responses and trigger a cascade of many of the inflammatory signals present in asthma.

  5. there is a strong association in a given patient between both nasal and pharyngeal EPX levels and the eosinophil percentage of induced sputum.

  6. Myeloperoxidase (zeige MPO Proteine) and eosinophil peroxidase are readily internalized by HUVEC cells where they promote cellular proliferation, migration, invasion, and stimulate angiogenesis both in vitro and in vivo.

  7. A preferential role of EPO (zeige EPO Proteine) signaling via a specific surface receptor that leads to neural plasticity.

  8. Eosinophil peroxidase in sputum represents a unique biomarker of airway eosinophilia.

  9. report the prevalence of a common SNP in the eosinophil protein x/eosinophil-derived neurotoxin (zeige RNASE2 Proteine) (EPX/EDN (zeige RNASE2 Proteine), RNase2 (zeige RNASE2 Proteine)) and the association with the cellular contents of EPX/EDN (zeige RNASE2 Proteine) and ECP (zeige ECP Proteine)

  10. Polymorphisms of EPX and ECP (zeige ECP Proteine) are associated to inflammatory bowel disease in an age and gender dependent manne.

Mouse (Murine) Eosinophil Peroxidase (EPX) Interaktionspartner

  1. The expression of MBP-1 (zeige ENO1 Proteine) and EPX was also required for induced lung expression of IL-4 (zeige IL4 Proteine)/IL-13 (zeige IL13 Proteine) in each setting and, in turn, the induced pulmonary remodeling events and lung dysfunction.

  2. EPO (zeige EPO Proteine)-mediated protein carbamylation is promoted during allergen-induced asthma exacerbation, and can both modulate immune responses and trigger a cascade of many of the inflammatory signals present in asthma.

  3. The absence of MBP-1 (zeige ENO1 Proteine) and EPX promoted a concomitant loss of eosinophil lineage-committed progenitors in the marrow, identifying a specific blockade in eosinophilopoiesis as the causative event.

  4. HER2 (zeige ERBB2 Proteine) was identified as a novel mediator of eosinophil peroxidase signaling. Eosinophil peroxidase, at noncytotoxic levels, can drive cell-cycle progression and proliferation.

  5. Host protection against Brugia pahangi infections was unimpaired in mice deficient in eosinophil peroxidase.

  6. Mice deficient for either eosinophil peroxidase or major basic protein on the 129/SvJ background developed significantly higher worm burdens than wild-type mice.

  7. post-translational tyrosine nitration of eosinophil granule toxins mediated by eosinophil peroxidase

  8. The activities of EPO (zeige EPO Proteine), an eosinophilic secondary granule protein, do not affect the development of allergic pulmonary pathologies in the mouse lung at levels comparable to those observed in humans with asthma.

EPX Protein Überblick

Protein Überblick

This gene is a member of the peroxidase gene family and is expressed in eosinophils. The encoded precursor protein is processed into covalently attached heavy and light chains to form the mature enzyme, which functions as an oxidant. The enzyme is released at sites of parasitic infection or allergen stimulation to mediate lysis of protozoa or parasitic worms. The gene is found in a cluster of three peroxidase genes at chromosome 17q23. Mutations in this gene result in eosinophil peroxidase deficiency.

Genbezeichner und Symbole assoziert mit Eosinophil Peroxidase Proteine (EPX)

  • eosinophil peroxidase (LOC788751)
  • eosinophil peroxidase (EPX)
  • eosinophil peroxidase L homeolog (epx.L)
  • eosinophil peroxidase (Epx)
  • EPO Protein
  • EPP Protein
  • EPX Protein
  • EPX-PEN Protein
  • pmr-1 Protein

Bezeichner auf Proteinebene für Eosinophil Peroxidase Proteine (EPX)

eosinophil peroxidase , polysomal ribonuclease 1 , eosinophil peroxidase-like

GENE ID SPEZIES
788751 Bos taurus
468420 Pan troglodytes
491109 Canis lupus familiaris
709655 Macaca mulatta
398084 Xenopus laevis
100437241 Pongo abelii
100473148 Ailuropoda melanoleuca
8288 Homo sapiens
13861 Mus musculus
303414 Rattus norvegicus
100514365 Sus scrofa
Ausgewählte Anbieter für EPX Proteine (EPX)
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