anti-EF-Hand Domain Family, Member D2 (EFHD2) Antikörper

May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis (By similarity). Zusätzlich bieten wir Ihnen EF-Hand Domain Family, Member D2 Kits (9) und EF-Hand Domain Family, Member D2 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
EFHD2 27984  
EFHD2 79180 Q96C19
EFHD2 298609 Q4FZY0
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Top anti-EF-Hand Domain Family, Member D2 Antikörper auf antikoerper-online.de

Showing 10 out of 41 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-EFHD2 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human Lung 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Ziege Unkonjugiert IHC (p), IHC, ELISA, WB ABIN250320 (0.03µg/ml) staining of Human Thymus lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. ABIN250320 (0.3?g/ml) staining of paraffin embedded Human Tonsil. Microwaved antigen retrieval with citrate buffer pH6, HRP-staining. Positive cells A) in the interfollicular area and surrounding a vessel, B) in proximity of the epithelial criptae. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$485.88
Details
Human Ziege Unkonjugiert IHC, ELISA, WB ABIN185311 (0.1µg/ml) staining of human lymph node lysate. Primary incubation was 1 hour. Detected by chemiluminescence. ABIN185311 (0.3µg/ml) staining of paraffin embedded human tonsil. Microwaved antigen retrieval with citrate buffer pH6, HRP-staining. Positive cells A) in the interfollicular area and surrounding a vessel, B) in proximity of the epithelial criptae. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Pferd Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Rind (Kuh) Ziege Unkonjugiert IHC (p), ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$610.50
Details
Human Ziege Unkonjugiert IHC (p), WB   0.1 mg Anmelden zum Anzeigen 10 bis 12 Tage
$455.40
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$368.50
Details
Human Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$446.88
Details
Human Kaninchen Unkonjugiert IHC (p), ELISA, WB Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$451.00
Details
Human Ziege Unkonjugiert IHC, ELISA, WB 0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$481.25
Details

EFHD2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Mouse (Murine) ,
,

Human ,
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Rat (Rattus) ,
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Am meisten referenzierte anti-EF-Hand Domain Family, Member D2 Antikörper

  1. Human Polyclonal EFHD2 Primary Antibody für IHC (p), IHC - ABIN250320 : Ferrer-Acosta, Rodríguez-Cruz, Orange, De Jesús-Cortés, Madera, Vaquer-Alicea, Ballester, Guinel, Bloom, Vega: EFhd2 is a novel amyloid protein associated with pathological tau in Alzheimer's disease. in Journal of neurochemistry 2013 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal EFHD2 Primary Antibody für IHC, ELISA - ABIN185311 : Vuadens, Rufer, Kress, Corthésy, Schneider, Tissot: Identification of swiprosin 1 in human lymphocytes. in Proteomics 2004 (PubMed)
    Show all 3 Pubmed References

Weitere Antikörper gegen EF-Hand Domain Family, Member D2 Interaktionspartner

Mouse (Murine) EF-Hand Domain Family, Member D2 (EFHD2) Interaktionspartner

  1. These results show that EFhd2 is not essential for platelet function in mice indicating that other cytoskeletal adaptors may functionally compensate its loss.

  2. EFhd2 is a neuronal protein that interferes with kinesin-mediated transport.

  3. a role is found for EFhd2 as a negative regulator of germinal center-dependent humoral type 2 immunity, with implications for the generation of IgE.

  4. Swiprosin-1 is involved in regulating the accessibility of F-actin to cofilin (zeige CFL1 Antikörper) through the clustering of F-actin and the activity of Swiprosin-1 is highly dependent on its phosphorylation status at Ser183

  5. Characterized EFhd2's calcium binding activity. Results showed mutations of a conserved aspartate on either EF-hand motif disrupted calcium binding activity, indicating that these motifs work in pair as a functional calcium binding domain.

  6. EFhd2 may play an important role in the pathobiology of tau-mediated neurodegeneration.

  7. Swip-1 (zeige WSB1 Antikörper) provides a membrane scaffold that is required for the Syk (zeige SYK Antikörper)-, SLP-65 (zeige BLNK Antikörper)-, and PLCgamma2 (zeige PLCG2 Antikörper)-dependent BCR (zeige BCR Antikörper)-induced calcium flux.

  8. study shows that swiprosin-1 may regulate lifespan and BCR (zeige BCR Antikörper) signaling thresholds in immature B cells

  9. The identification of a novel calcium-binding protein (zeige GUCA1B Antikörper) associated with tau protein in terminally ill tauopathy mouse model suggests that this association may play an important physiological and/or pathological role.

  10. These results suggest that swiprosin-1 is a PKC-beta (zeige PRKCB Antikörper) I/eta-inducible gene and it modulates mast cell activation through NF-kappaB (zeige NFKB1 Antikörper)-dependent pathway.

Human EF-Hand Domain Family, Member D2 (EFHD2) Interaktionspartner

  1. Phosphorylation at Ser183 of EFhd2 causes changes in the local conformational dynamics and the surface charge distribution of the actin-binding site, resulting in a re-coordination of the actin-binding sites in the dimer structure.

  2. The results imply that EFhd2's physiological and/or pathological function could be regulated by its phosphorylation state.

  3. EFhd2 is involved in the control of synapse development and maintenance and is linked to dementia.

  4. Swiprosin-1 localizes to microvilli-like membrane protrusions and lamellipodia and exhibits actin-binding activity.

  5. Swiprosin-1 is involved in regulating the accessibility of F-actin to cofilin (zeige CFL1 Antikörper) through the clustering of F-actin and the activity of Swiprosin-1 is highly dependent on its phosphorylation status at Ser183

  6. EFhd2 may play an important role in the pathobiology of tau-mediated neurodegeneration.

  7. the human Shu complex (hSWS1.SWSAP1 (zeige SWSAP1 Antikörper)) has an evolutionarily conserved function in homologous recombination

  8. Its predominant presence in CD8 (zeige CD8A Antikörper) lymphocytes suggests that swiprosin-1 may be involved in functions that are important for cytotoxic lymphocytes.

  9. These results suggest that swiprosin-1 is a PKC-beta (zeige PRKCB Antikörper) I/eta-inducible gene and it modulates mast cell activation through NF-kappaB (zeige NFKB1 Antikörper)-dependent pathway.

EF-Hand Domain Family, Member D2 (EFHD2) Antigen-Profil

Protein Überblick

May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis (By similarity). Plays a role as negative regulator of the canonical NF-kappa-B-activating branch (By similarity). Controls spontaneous apoptosis through the regulation of BCL2L1 abundance (By similarity).

Genbezeichner und Symbole assoziert mit EFHD2

  • EF-hand domain family member D2 (EFHD2) Antikörper
  • EF-hand domain family member D2 (efhd2) Antikörper
  • EF-hand domain family member D2 L homeolog (efhd2.L) Antikörper
  • EF-hand domain family, member D2 (efhd2) Antikörper
  • EF hand domain containing 2 (Efhd2) Antikörper
  • EF-hand domain family, member D1 (efhd1) Antikörper
  • EF-hand domain family, member D2 (Efhd2) Antikörper
  • 2600015J22Rik Antikörper
  • AA408606 Antikörper
  • D4Wsu27e Antikörper
  • EFHD2 Antikörper
  • fj19b07 Antikörper
  • MGC131292 Antikörper
  • si:ch211-281l24.1 Antikörper
  • si:dkey-72l14.9 Antikörper
  • SWS1 Antikörper
  • wu:fb80e07 Antikörper
  • wu:fj19b07 Antikörper

Bezeichner auf Proteinebene für EFHD2

EF-hand domain family, member D2 , EF hand domain family, member D2 , EF-hand domain-containing protein D2 , swiprosin 1 , swiprosin-1 , EF hand domain containing 2

GENE ID SPEZIES
430669 Gallus gallus
496711 Xenopus (Silurana) tropicalis
694155 Macaca mulatta
735013 Xenopus laevis
747200 Pan troglodytes
100345208 Oryctolagus cuniculus
100380618 Salmo salar
571114 Danio rerio
27984 Mus musculus
335521 Danio rerio
79180 Homo sapiens
298609 Rattus norvegicus
514259 Bos taurus
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