anti-E4F Transcription Factor 1 (E4F1) Antikörper

The zinc finger protein encoded by E4F1 is one of several cellular transcription factors whose DNA-binding activities are regulated through the action of adenovirus E1A. Zusätzlich bieten wir Ihnen E4F1 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
E4F1 1877 Q66K89
E4F1 13560 Q8CCE9
E4F1 681359  
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Top anti-E4F1 Antikörper auf antikoerper-online.de

Showing 10 out of 22 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Maus Unkonjugiert WB Western Blot analysis of E4F1 expression in transfected 293T cell line by E4F1 monoclonal antibody (M03), clone 4B10. Lane 1: E4F1 transfected lysate(83.5 KDa). Lane 2: Non-transfected lysate. 0.1 mg Anmelden zum Anzeigen 12 bis 16 Tage
454,76 €
Details
Human Kaninchen Unkonjugiert IP, WB 100 μL Anmelden zum Anzeigen 2 bis 4 Tage
371,00 €
Details
Human Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 4 Tage
371,00 €
Details
Human Kaninchen Unkonjugiert ICC, IF Immunocytochemistry/Immunofluorescence: E4F1 Antibody  - Staining of human cell line MCF7 shows localization to nucleoplasm. 100 μL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Human Kaninchen Unkonjugiert ICC, IF, WB Western Blot: E4F1 Antibody  - Western blot analysis in human cell line RT-4 and human cell line U-251 MG. Immunocytochemistry/Immunofluorescence: E4F1 Antibody  - Staining of human cell line MCF7 shows localization to nucleoplasm. 100 μL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Human Maus Unkonjugiert IF, ELISA, WB Western Blot analysis of E4F1 expression in transfected 293T cell line by E4F1 monoclonal antibody (M03), clone 4B10.<br><br>Lane 1: E4F1 transfected lysate(83.5 KDa).<br>Lane 2: Non-transfected lysate.<br> Detection limit for recombinant GST tagged E4F1 is 0.1 ng/ml as a capture antibody. 100 μg Anmelden zum Anzeigen 7 bis 8 Tage
369,60 €
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB   100 μL Anmelden zum Anzeigen 9 bis 12 Tage
304,36 €
Details
Human Maus Unkonjugiert IF, WB Western Blot analysis of E4F1 expression in transfected 293T cell line by E4F1 MaxPab polyclonal antibody.<br><br>Lane 1: E4F1 transfected lysate(86.24 KDa).<br>Lane 2: Non-transfected lysate.<br> Immunofluorescence of <u>purified</u> MaxPab antibody to E4F1 on HeLa cell. [antibody concentration 10 ug/ml] 50 μL Anmelden zum Anzeigen 7 bis 8 Tage
369,60 €
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Rind (Kuh) Kaninchen Unkonjugiert IP, WB   100 μL Anmelden zum Anzeigen 11 bis 14 Tage
705,40 €
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Human Maus Unkonjugiert ELISA, IF, IHC (p), WB   50 μg Anmelden zum Anzeigen 11 bis 14 Tage
801,43 €
Details

E4F1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Human ,
,
,
Mouse (Murine)


Rat (Rattus)


Weitere Antikörper gegen E4F1 Interaktionspartner

Human E4F Transcription Factor 1 (E4F1) Interaktionspartner

  1. Whole exome sequencing has unraveled the presence of pathogenic mutations in genes encoding non-mitochondrial proteins, such as in the transcription factor E4F1.

  2. results suggest that E4F1 may neutralize the capacity of HBx to activate a p53 (zeige TP53 Antikörper)-dependent, metabolic and growth arrest phenotype in liver cells, thus possibly contributing to the viability and proliferation of HBV-infected cells

  3. Short hairpin RNA-mediated depletion of E4F1 induced mitochondrial defects and ROS-mediated death in several myeloid leukemia cell lines.

  4. association of p120E4F with p14ARF (zeige CDKN2A Antikörper) enhances cell cycle inhibition

  5. Specific inactivation of RASSF1A (zeige RASSF1 Antikörper) by short interfering RNA disrupts binding of RASSF1A (zeige RASSF1 Antikörper) to p120 (zeige HNRNPU Antikörper)(E4F) in tumor cells.

  6. E4F1 function involves ER alpha (zeige ESR1 Antikörper)-mediated inhibition of VSMC proliferation and estrogen-related atheroprotection of human

  7. findings show that full-length E4F1 protein but not its E1A (zeige BCKDHA Antikörper)-activated & truncated form interacts in vitro & in vivo with FHL2 (zeige FHL2 Antikörper); this E4F1-FHL2 (zeige FHL2 Antikörper) association occurs in the nuclear compartment & inhibits the capacity of E4F1 to block cell proliferation

  8. E4F1 is a key posttranslational regulator of p53 (zeige TP53 Antikörper), which modulates its effector functions involved in alternative cell fates: growth arrest or apoptosis.

  9. LANP (zeige ANP32A Antikörper) and ATAXN1 interact in E4F-mediated transcriptional repression.

Mouse (Murine) E4F Transcription Factor 1 (E4F1) Interaktionspartner

  1. Acute inactivation of E4F1 in these cells results in CHK1 (zeige CHEK1 Antikörper)-dependent checkpoint deficiency and multiple mitochondrial dysfunctions that lead to increased ROS (zeige ROS1 Antikörper) production, energy stress, and inhibition of de novo pyrimidine synthesis

  2. Altogether, our results classify E4F1 as a master regulator of CHK1 (zeige CHEK1 Antikörper) activity that ensures high fidelity of DNA replication, thus safeguarding genome stability.

  3. deletion of E4F1 resulted in the death of histiocytic sarcoma cells and tumor regression in vivo and extended the lifespan

  4. identify a regulatory axis essential for epidermal stem cell-dependent skin homeostasis implicating E4F1 and the Bmi1 (zeige BMI1 Antikörper)-Arf (zeige CDKN2A Antikörper)-p53 (zeige TP53 Antikörper) pathway.

  5. Results establish a crucial role for E4F during early embryonic cell cycles and reveal an unexpected function for E4F in mitosis.

E4F1 Antigen-Profil

Protein Überblick

The zinc finger protein encoded by this gene is one of several cellular transcription factors whose DNA-binding activities are regulated through the action of adenovirus E1A. A 50-kDa amino-terminal product is generated from the full-length protein through proteolytic cleavage. The protein is differentially regulated by E1A-induced phosphorylation. The full-length gene product represses transcription from the E4 promoter in the absence of E1A, while the 50-kDa form acts as a transcriptional activator in its presence.

Genbezeichner und Symbole assoziert mit E4F1

  • E4F transcription factor 1 (E4F1) Antikörper
  • E4F transcription factor 1 (e4f1) Antikörper
  • E4F transcription factor 1 (LOC100224725) Antikörper
  • E4F transcription factor 1 (E4f1) Antikörper
  • Dnase1l2 Antikörper
  • E4F Antikörper
  • MGC147041 Antikörper
  • zgc:114190 Antikörper

Bezeichner auf Proteinebene für E4F1

transcription factor E4F1 , E4F transcription factor 1 , p120E4F , transcription factor E4F1-like , p50E4F , putative E3 ubiquitin-protein ligase E4F1 , transcription factor E4F , transcription factor phi AP3 , deoxyribonuclease 1-like 2

GENE ID SPEZIES
515997 Bos taurus
100517704 Sus scrofa
100683433 Canis lupus familiaris
416560 Gallus gallus
454356 Pan troglodytes
548399 Xenopus (Silurana) tropicalis
695882 Macaca mulatta
100190769 Xenopus laevis
100224725 Taeniopygia guttata
100404813 Callithrix jacchus
100552753 Anolis carolinensis
100580177 Nomascus leucogenys
1877 Homo sapiens
13560 Mus musculus
681359 Rattus norvegicus
561158 Danio rerio
Ausgewählte Anbieter für anti-E4F1 (E4F1) Antikörper
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