anti-Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1) Antikörper

DMRT1 is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). Zusätzlich bieten wir Ihnen DMRT1 Proteine (11) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
DMRT1 1761 Q9Y5R6
DMRT1 50796 Q9QZ59
DMRT1 114498  
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Top anti-DMRT1 Antikörper auf antikoerper-online.de

Showing 10 out of 66 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-DMRT1 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>Human brain 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Maus Kaninchen Unkonjugiert WB <b>WB Suggested Anti-Dmrt1 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>NIH/3T3 cell lysate WB Suggested Anti-Dmrt1 <br /> Antibody Titration: 0.2-1 µg/mL <br /> Positive Control: NIH/3T3 cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
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Human Kaninchen Unkonjugiert IHC (p), WB Anti- DMRT1 antibody,IHC(P) IHC(P): Human Testis Tissue 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
298,57 €
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: DMRT1 Antibody [NBP1-84071] - Staining of human cell line U-251MG shows positivity in nucleus but not nucleoli. Immunohistochemistry-Paraffin: DMRT1 Antibody [NBP1-84071] - Staining of human testis shows strong nuclear positivity in fraction of cells in seminiferus ducts. 0.1 mL Anmelden zum Anzeigen 13 bis 15 Tage
335,00 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB   100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert WB DMRT1 Antibody (C-term)  western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the DMRT1 antibody detected the DMRT1 protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
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Rind (Kuh) Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
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Human Kaninchen Unkonjugiert WB WB Image Sample (30 ug of whole cell lysate) A: K562 10% SDS PAGE antibody diluted at 1:3000 100 μL Anmelden zum Anzeigen 5 bis 7 Tage
357,24 €
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Human Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
459,65 €
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Human Kaninchen Unkonjugiert WB Western blot analysis of extracts of HL-60 cells, using DMRT1 antibody. 100 μL Anmelden zum Anzeigen 12 Days
261,90 €
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DMRT1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-DMRT1 Antikörper

  1. Human Polyclonal DMRT1 Primary Antibody für IHC, IHC (p) - ABIN4305451 : von Kopylow, Staege, Spiess, Schulze, Will, Primig, Kirchhoff: Differential marker protein expression specifies rarefaction zone-containing human Adark spermatogonia. in Reproduction (Cambridge, England) 2012 (PubMed)
    Show all 3 Pubmed References

Weitere Antikörper gegen DMRT1 Interaktionspartner

Zebrafish Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1) Interaktionspartner

  1. dmrt1 functions in male sexual fate in zebrafish and is essential for normal development of testis tubules and spermatogenesis.

  2. Data indicate taht monocrotophos (MCP) exposure modulated gene expression of forkhead transcription factor gene L2 (foxl2), doublesex/mab-3 related transcription factor 1 (dmrt1), gonadal aromatase (cyp19a1a) and brain aromatase (cyp19a1b).

  3. Dmrt1 gene is not only associated with testis development, but also, may be important in ovary differentiation of zebrafish

Human Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1) Interaktionspartner

  1. DMRT1 might influence sex-specific patterns of childhood asthma, and its expression in testis tissue and lung macrophages suggests a potential involvement in hormone or immune cell regulation.

  2. The results suggest a role of changes in DMRT1 dosage in non-obstructive azoospermia potentially also through a process of gene misregulation, even though DMRT1 deleterious variants seem to be rare.

  3. The role of DMT1 in mitochondrial iron acquisition by immunofluorescence with mitochondrial markers in cells and isolated mitochondria, as well as flow cytometric quantification of DMT1-positive mitochondria from an inducible expression system.

  4. Point mutations of DMRT1 may be rarely associated with male infertility.

  5. The combined results indicate that DMRT1 loss-of-function mutations are a risk factor and potential genetic cause of human spermatogenic failure

  6. neither DMRT1 nor FGF9 abnormalities are frequently involved in dysgenetic male gonad development in patients with non-syndromic 46,XY disorder of sex development.

  7. Meiosis signalling is dysregulated in carcinoma in situ (CIS (zeige CISH Antikörper)) cells and that a key regulator of the mitosis-meiosis switch, DMRT1, is expressed in 'early-stage' CIS (zeige CISH Antikörper) cells but is down-regulated with further invasive transformation.

  8. The biological importance of the changes in expression of DMRT1 in Sertoli cells remains to be established, but it is consistent with DMRT1 reinforcing the inhibition of meiosis in the testis.

  9. variants in or near BAK1 (zeige BAK1 Antikörper), DMRT1, TERT (zeige TERT Antikörper)-CLPTM1L (zeige CLPTM1L Antikörper), and KITLG (zeige KITLG Antikörper) predispose to familial and bilateral TGCT.

  10. There is evidence that DMT1 expression and function respond rapidly to changes in dietary iron content

Mouse (Murine) Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1) Interaktionspartner

  1. Concluding, this study shows that, in addition to its crucial role in testis development, Sox9 (zeige SOX9 Antikörper), together with Sox8 (zeige SOX8 Antikörper) and coordinately with Dmrt1, also controls adult testis maintenance.

  2. miR (zeige MLXIP Antikörper)-224 overexpression increases the expression of GFRalpha1 (zeige GFRA1 Antikörper) and PLZF (zeige ZBTB16 Antikörper), accompanied by the down-regulation of DMRT1 in mouse testes.

  3. Dmrt1 supports spermatogonial stem cell pool homeostasis.

  4. DMRT1 expression in the ovary silenced the female sex-maintenance gene Foxl2 (zeige FOXL2 Antikörper) and reprogrammed juvenile and adult granulosa cells into Sertoli-like cells, triggering formation of structures resembling male seminiferous tubules.

  5. Enforced expression of Dmrt1 in XX mouse fetal gonads using a Wt1 (zeige WT1 Antikörper)-BAC transgene system is sufficient to drive testicular differentiation and male secondary sex development.

  6. spontaneous SSC (zeige CYP11A1 Antikörper) reprogramming is caused by unstable DNA methylation (zeige HELLS Antikörper) and that a Dmrt1-Sox2 (zeige SOX2 Antikörper) cascade is critical for regulating pluripotency in SSCs

  7. DMRT1 controls pluripotency via transcriptional repression of Esrrb, Nr5a2/Lrh1 (zeige NR5A2 Antikörper), and Sox2 (zeige SOX2 Antikörper).

  8. DMRT1 controls Stra8 (zeige STRA8 Antikörper) sex-specifically, activating it in the fetal ovary and repressing it in the adult testis.

  9. sexual fate is surprisingly labile in the testis: loss of the DMRT1 transcription factor in mouse Sertoli cells, even in adults, activates Foxl2 (zeige FOXL2 Antikörper) and reprograms Sertoli cells into granulosa cells

  10. These results suggest that novel ncRNA gene Dmr (zeige WDR20 Antikörper) might play a negative regulatory role for Dmrt1 in male sexual development.

DMRT1 Antigen-Profil

Protein Überblick

This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous.

Genbezeichner und Symbole assoziert mit DMRT1

  • doublesex and mab-3 related transcription factor 1 (dmrt1) Antikörper
  • doublesex and mab-3 related transcription factor 1 (DMRT1) Antikörper
  • doublesex and mab-3 related transcription factor 1 (DMRT-1) Antikörper
  • doublesex and mab-3 related transcription factor 1 (Dmrt1) Antikörper
  • dmrt1 Antikörper
  • DMT1 Antikörper
  • zgc:136676 Antikörper

Bezeichner auf Proteinebene für DMRT1

doublesex- and mab-3-related transcription factor 1 , doublesex and mab-3 related transcription factor 1 , DM domain-containing transcription factor DMRT1 , DM domain expressed in testis 1 , DM domain expressed in testis protein 1

GENE ID SPEZIES
402923 Danio rerio
473158 Pan troglodytes
654281 Takifugu rubripes
697441 Macaca mulatta
100135897 Oncorhynchus mykiss
100174882 Gasterosteus aculeatus
100580439 Nomascus leucogenys
1761 Homo sapiens
609186 Canis lupus familiaris
397199 Sus scrofa
616245 Bos taurus
50796 Mus musculus
114498 Rattus norvegicus
769693 Gallus gallus
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