anti-Differentially Expressed in FDCP 6 Homolog (Mouse) (DEF6) Antikörper

DEF6, or IBP, is a guanine nucleotide exchange factor (GEF) for RAC (MIM 602048) and CDC42 (MIM 116952) that is highly expressed in B and T cells (Gupta et al., 2003 [PubMed 12923183]).[supplied by OMIM, Mar 2008].. Zusätzlich bieten wir Ihnen DEF6 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
DEF6 23853 Q8C2K1
DEF6 50619 Q9H4E7
DEF6 309642  
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Top anti-DEF6 Antikörper auf antikoerper-online.de

Showing 10 out of 68 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-DEF6 Antibody Titration: 1.0 ug/ml Positive Control: U937 Whole Cell 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert EIA, WB western blot analysis of DEF6 Antibody (C-term) in A375 cell line lysates (35ug/lane). This demonstrates the DEF6 antibody detected the DEF6 protein (arrow). 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Ziege Unkonjugiert ELISA, WB ABIN185227 (1µg/ml) staining of Human Thymus lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 3 bis 4 Tage
349,82 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Fledermaus Ziege Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
722,86 €
Details
Human Kaninchen Unkonjugiert WB DEF6 Antibody (C-term)  western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the DEF6 antibody detected the DEF6 protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Maus Unkonjugiert IHC (p), IP, ELISA, WB Immunoperoxidase of monoclonal antibody to DEF6 on formalin-fixed paraffin-embedded human lymph node [antibody concentration 3 ug/ml] Detection limit for recombinant GST tagged DEF6 is approximately 1ng/ml as a capture antibody. 50 μg Anmelden zum Anzeigen 7 bis 8 Tage
369,60 €
Details
Hund Maus Unkonjugiert IF, IHC (p), WB 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
583,17 €
Details
Human Maus Unkonjugiert IHC (p), WB 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
583,17 €
Details
Human Maus Unkonjugiert IF, IHC (p), WB 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
583,17 €
Details

DEF6 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Mouse (Murine) ,
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Am meisten referenzierte anti-DEF6 Antikörper

  1. Human Monoclonal DEF6 Primary Antibody für IHC (p), IP - ABIN565491 : Worthmann, Leitges, Teng, Sestu, Tossidou, Samson, Haller, Huber, Schiffer: Def-6, a novel regulator of small GTPases in podocytes, acts downstream of atypical protein kinase C (aPKC) ?/?. in The American journal of pathology 2013 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal DEF6 Primary Antibody für ELISA, WB - ABIN268577 : Tanaka, Bi, Kitamura, Hong, Altman, Matsumoto, Tabata, Lebedeva, Bushway, Altman: SWAP-70-like adapter of T cells, an adapter protein that regulates early TCR-initiated signaling in Th2 lineage cells. in Immunity 2003 (PubMed)

Weitere Antikörper gegen DEF6 Interaktionspartner

Zebrafish Differentially Expressed in FDCP 6 Homolog (Mouse) (DEF6) Interaktionspartner

  1. Swap70b and Def6a delineate Wnt11 (zeige WNT11 Antikörper) and Wnt5b (zeige WNT5B Antikörper) signalling pathways and have roles in convergent and extension cell movement during zebrafish gastrulation

  2. def6 morphants phenocopy Wnt5b (zeige WNT5B Antikörper) mutants and ectopic overexpression of def6 essentially rescues Wnt5b (zeige WNT5B Antikörper) morphants, indicating a novel role for def6 as a central GEF (zeige SLC2A4RG Antikörper) downstream of Wnt5b (zeige WNT5B Antikörper) signaling

Mouse (Murine) Differentially Expressed in FDCP 6 Homolog (Mouse) (DEF6) Interaktionspartner

  1. DEF6 and SWAP70 (zeige SWAP70 Antikörper) are SWEF proteins with important contributors to hematopoietic stem and precursor cells biology

  2. this study identifies Def6 as a novel inhibitor of osteoclastogenesis in physiological and inflammatory conditions

  3. These findings ascribe a new function to SLAT, and identify Rap1 as a target of SLAT function in TCR-mediated inside-out signaling.

  4. SLAT is an IP3R1 (zeige ITPR1 Antikörper)-interacting protein required for T cell activation.

  5. PKClambda/iota was identified as an important factor for actin cytoskeletal regulation in podocytes and Def-6 as a specific downstream target of PKClambda/iota that regulates the activity of small GTPases and subsequently the actin cytoskeleton of podocytes.

  6. Data suggest that SLAT acts as a negative modulator of RANKL (zeige TNFSF11 Antikörper)-induced osteoclastogenesis.

  7. SLAT-mediated nuclear factor of activated T-cell (zeige NFATC3 Antikörper) (NFAT)1 (zeige NFAT1 Antikörper) activation is required for efficient expansion of CD8 (zeige CD8A Antikörper)+ T cells during the primary response but is not necessary for cytotoxic T lymphocyte (CTL) differentiation.

  8. SLAT/Def6 plays a major role in the T cell-mediated autoimmune processes that bring about the inflammatory eye disease, experimental autoimmune uveitis.

  9. plays a role in Th2 development and/or activation, perhaps by interfering with ZAP-70 (zeige ZAP70 Antikörper) signaling

  10. tyrosine-phosphorylation-mediated relocalization of SLAT to the site of antigen recognition is required for SLAT to exert its pivotal role in NFAT (zeige NFATC1 Antikörper)-dependent CD4 (zeige CD4 Antikörper)(+) T cell differentiation.

Human Differentially Expressed in FDCP 6 Homolog (Mouse) (DEF6) Interaktionspartner

  1. this study identifies Def6 (zeige DEFA6 Antikörper) as a novel inhibitor of osteoclastogenesis in physiological and inflammatory conditions

  2. DEF6 (zeige DEFA6 Antikörper) expression may serve as an independent prognostic factor, and interacted positively with p16 (zeige CDKN2A Antikörper) toward high tumor stage and shorter survival.

  3. IBP (zeige TSPO Antikörper) was expressed ectopically in someoral squamous cell carcinoma samples and correlated significantly with tumor size, differentiation, clinical stage and distant metastases

  4. DEF6 (zeige DEFA6 Antikörper), a novel substrate for the Tec (zeige NR4A3 Antikörper) kinase ITK (zeige ITK Antikörper), contains a glutamine (zeige GFPT1 Antikörper)-rich aggregation-prone region and forms cytoplasmic granules that co-localize with P-bodies.

  5. Molecular cloning of IBP (zeige TSPO Antikörper), a guanine nucleotide exchange factor (zeige RASGRF1 Antikörper), which is highly expressed in the immune system.

  6. IBP (zeige TSPO Antikörper) is a novel guanine nucleotide exchange factor (zeige RASGRF1 Antikörper) and is recruited to the immunological synapse by T cell receptor engagement

  7. DEF6 not only activates Rho-family GTPases but also cooperates with activated Rac1 to exert its cellular function

  8. Overexpression of the Interferon regulatory factor 4 (zeige IRF4 Antikörper)-binding protein is associated with Colorectal Carcinoma.

  9. DEF6 (zeige DEFA6 Antikörper), a novel PH-DH-like domain protein, is an upstream activator of the Rho GTPases Rac1, Cdc42 (zeige CDC42 Antikörper), and RhoA (zeige RHOA Antikörper).

DEF6 Antigen-Profil

Protein Überblick

DEF6, or IBP, is a guanine nucleotide exchange factor (GEF) for RAC (MIM 602048) and CDC42 (MIM 116952) that is highly expressed in B and T cells (Gupta et al., 2003

Genbezeichner und Symbole assoziert mit DEF6

  • differentially expressed in FDCP 6 homolog (mouse) (DEF6) Antikörper
  • differentially expressed in FDCP 6a homolog (mouse) (def6a) Antikörper
  • differentially expressed in FDCP 6 homolog (def6) Antikörper
  • differentially expressed in FDCP 6 homolog (LOC100498543) Antikörper
  • differentially expressed in FDCP 6 (Def6) Antikörper
  • differentially expressed in FDCP 6 homolog (mouse) (Def6) Antikörper
  • 2410003F05Rik Antikörper
  • 6430538D02Rik Antikörper
  • AV094905 Antikörper
  • Def6 Antikörper
  • IBP Antikörper
  • MGC68775 Antikörper
  • SLAT Antikörper
  • Slat2 Antikörper
  • Slat6 Antikörper
  • SWAP70L Antikörper
  • zgc:63721 Antikörper

Bezeichner auf Proteinebene für DEF6

differentially expressed in FDCP 6 homolog (mouse) , differentially expressed in FDCP 6 homolog , DEF-6 , IRF-4-binding protein , IRF4-binding protein , SWAP-70-like adapter of T-cells , SWAP-70-like adaptor protein of T cells

GENE ID SPEZIES
419893 Gallus gallus
462636 Pan troglodytes
394015 Danio rerio
398924 Xenopus laevis
100498543 Xenopus (Silurana) tropicalis
100053351 Equus caballus
23853 Mus musculus
50619 Homo sapiens
608163 Canis lupus familiaris
100154998 Sus scrofa
516457 Bos taurus
309642 Rattus norvegicus
Ausgewählte Anbieter für anti-DEF6 (DEF6) Antikörper
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