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Deleted In Azoospermia 4 Proteine (DAZ4)

DAZ4 is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Zusätzlich bieten wir Ihnen Deleted In Azoospermia 4 Antikörper (49) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
DAZ4 57135 Q86SG3
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Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 16 Days
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DAZ4 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,

Weitere Proteine zu Deleted In Azoospermia 4 (DAZ4) Interaktionspartnern

Human Deleted In Azoospermia 4 (DAZ4) Interaktionspartner

  1. study reported a new type of AZFc deletion (gr/gr (zeige GSR Proteine)-DAZ2-DAZ4-CDY1b (zeige CDY2A Proteine)) and hypothesis that this new deletion is the result of 2 successive events favored by the unstable structure of AZFc region; also demonstrated that this deletion constitutes a relative high-risk factor for male infertility in Tunisian population

  2. Studies indicate that partial RNA-binding proteins DAZ1 (zeige DAZ1 Proteine)/2 deletion was associated wih male infertility, but partial RNA-binding proteins DAZ3 (zeige DAZ3 Proteine)/4 deletion was not associated with male infertility.

  3. Oligospermia seems to be promoted by removing DAZ4 copy. Deletion of DAZ2 and DAZ4 gene copies is associated with male infertility.

  4. a common variant of the human Y chromosome lacks the DAZ3 (zeige DAZ3 Proteine)/DAZ4 and BPY2.2/BPY2.3 doublets in distal AZFc and thus these genes cannot be required for male fertility

  5. All four DAZ genes are expressed in the human testis, and their products are highly polymorphic among men

Deleted In Azoospermia 4 (DAZ4) Protein Überblick

Protein Überblick

This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications\; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat\; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified\; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains two copies of the 10.8 kb repeat. Alternatively spliced transcript variants encoding different isoforms have been described.

Genbezeichner und Symbole assoziert mit DAZ4

  • deleted in azoospermia 2 (DAZ2)
  • deleted in azoospermia 3 (DAZ3)
  • deleted in azoospermia 4 (DAZ4)
  • DAZ2 Protein
  • DAZ3 Protein
  • DAZ4 Protein
  • pDP1680 Protein
  • pDP1681 Protein

Bezeichner auf Proteinebene für DAZ4

deleted in azoospermia 2 , deleted in azoospermia 4 , deleted in azoospermia 3 , deleted in azoospermia protein 4

GENE ID SPEZIES
738583 Pan troglodytes
738636 Pan troglodytes
749910 Pan troglodytes
57135 Homo sapiens
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