anti-Cytoskeleton Associated Protein 2 (CKAP2) Antikörper

CKAP2 is a cytoskeleton-associated protein involved in mitotic progression (Seki and Fang, 2007. Zusätzlich bieten wir Ihnen Cytoskeleton Associated Protein 2 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CKAP2 26586 Q8WWK9
CKAP2 80986 Q3V1H1
CKAP2 306575  
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Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
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Rind (Kuh) Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
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Human Maus Unkonjugiert IHC (p), ELISA, WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
635,55 €
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Human Kaninchen Unkonjugiert IP, WB 100 μL Anmelden zum Anzeigen 2 bis 4 Tage
371,00 €
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Human Kaninchen Unkonjugiert IP 100 μL Anmelden zum Anzeigen 2 bis 4 Tage
371,00 €
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Human Kaninchen Alexa Fluor 594 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen Cy5.5 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen HRP IHC (p), WB   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen Cy5 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen Alexa Fluor 488 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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CKAP2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Weitere Antikörper gegen Cytoskeleton Associated Protein 2 Interaktionspartner

Human Cytoskeleton Associated Protein 2 (CKAP2) Interaktionspartner

  1. Chromatin CKAP2 is an independent prognostic marker for relapse-free survival in early-stage breast cancer, and could potentially replace the mitotic activity index in clinical evaluation of proliferation activity.

  2. The transcriptional activity of RHOA (zeige RHOA Antikörper), SEMA3B (zeige SEMA3B Antikörper), and CKAP2 genes was assessed in blood samples of leukaemia patients and healthy donors.

  3. CKAP2 is involved in the maintenance of microtubule nucleation sites

  4. GC box was responsible for the cyclic activity of human CKAP2 promoter through the phosphorylation of Sp1 (zeige PSG1 Antikörper), possibly by Cyclin A (zeige CCNA2 Antikörper)/Cdk (zeige CDK4 Antikörper) complex.

  5. Findings suggest that the motif surrounding Ser627 ((625) RRSRRL (630)) is a critical for kinase-substrate recognition and for regulation of the subcellular localization of TMAP during mitosis.

  6. TMAP is limited to pre-anaphase stages and suggest that the multiple phosphorylation may not act in concert but serve diverse functions.

  7. CKAP2 comprises nine exons ranging 70-1442 bp and is about 22 kb in size (regulatory regions included). The CKAP2 promoter contains CCAAT (-39...-33) rather than the canonical TATA box, and harbors nine binding sites for six transcription factors

  8. Data show that degradation of TMAP/CKAP2 during mitotic exit is mediated by the anaphase-promoting complex bound to Cdh1 (zeige CDH1 Antikörper) and that the KEN (zeige PCNT Antikörper) box motif near the N terminus is necessary for its destruction.

  9. CKAP2 is a physiological substrate of anaphase-promoting complex (zeige CDC26 Antikörper)/cyclosome during mitotic exit and that a tight regulation of the CKAP2 protein level is critical for the normal mitotic progression.

  10. Cdk1 (zeige CDK1 Antikörper)-cyclin B1 (zeige CCNB1 Antikörper)-mediated phosphorylation of TMAP is important for and contributes to proper regulation of microtubule dynamics and establishment of functional bipolar spindles during mitosis

Mouse (Murine) Cytoskeleton Associated Protein 2 (CKAP2) Interaktionspartner

  1. we found that Lb1-null epicardial cells have a delayed nuclear morphology change in vivo, suggesting that Lb1 facilitates morphological changes associated with migration. These findings suggest that Lb1 contributes to nuclear shape maintenance and migration of epicardial cells

  2. These data suggest a physiological role of CKAP2 in the formation of spindle bipolarity, which is necessary for maintaining chromosomal stability.

  3. These findings suggest that CKAP2 is a new MAP with microtubule-stabilizing properties

  4. Data suggest the existence of a functional positive feedback loop in which Ckap2 activates the G1 tetraploidy checkpoint and prevents aneuploidy.

  5. The cellular functions of TMAP/CKAP2 might be regulated by timely phosphorylation and dephosphorylation during the course of mitosis.

  6. Our present findings demonstrate that TMAP/CKAP2 is essential for proper chromosome segregation and for maintaining genomic stability.

Cytoskeleton Associated Protein 2 (CKAP2) Antigen-Profil

Protein Überblick

CKAP2 is a cytoskeleton-associated protein involved in mitotic progression (Seki and Fang, 2007

Genbezeichner und Symbole assoziert mit CKAP2

  • cytoskeleton associated protein 2 (CKAP2) Antikörper
  • cytoskeleton associated protein 2 (Ckap2) Antikörper
  • AI461656 Antikörper
  • AW228814 Antikörper
  • LB1 Antikörper
  • se20-10 Antikörper
  • TMAP Antikörper

Bezeichner auf Proteinebene für CKAP2

cytoskeleton-associated protein 2 , intracellular protein , cytoskeleton associated protein 2 , cytoskeleton-associated protein 2-like , CTCL tumor antigen se20-10 , tumor- and microtubule-associated protein , tumor-associated microtubule-associated protein

GENE ID SPEZIES
100052303 Equus caballus
418882 Gallus gallus
100515274 Sus scrofa
26586 Homo sapiens
80986 Mus musculus
306575 Rattus norvegicus
515249 Bos taurus
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