anti-Cytochrome P450, Family 8, Subfamily B, Polypeptide 1 (CYP8B1) Antikörper

Involved in bile acid synthesis and is responsible for the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7 alpha, 12 alpha-dihydroxy-4-cholesten-3-one. Zusätzlich bieten wir Ihnen CYP8B1 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CYP8B1 81924  
CYP8B1 1582 Q9UNU6
CYP8B1 13124 O88962
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Top anti-CYP8B1 Antikörper auf antikoerper-online.de

Showing 10 out of 46 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB WB Suggested Anti-CYP8B1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HepG2 cell lysate WB Suggested Anti-CYP8B1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: HepG2 cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
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Human Kaninchen Unkonjugiert EIA, WB   0.4 mL Anmelden zum Anzeigen 8 bis 11 Tage
357,50 €
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Human Kaninchen Unkonjugiert IHC, ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
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Human Kaninchen Unkonjugiert ELISA, IHC, WB 100 μL Anmelden zum Anzeigen 13 Days
154,33 €
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Human Kaninchen Unkonjugiert FACS, IHC (p), WB Western blot analysis of CYP8B1 Antibody (C-term) (ABIN652734) in K562 cell line lysates (35 µg/lane). CYP8B1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with MAPRE1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
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Human Kaninchen Unkonjugiert WB Western blot analysis of Cytochrome P450 8B1 expression in K562 (A), SP2/0 (B), PC12 (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 11 bis 13 Tage
464,29 €
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Human Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
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Human Maus Unkonjugiert ELISA, IHC, WB Immunohistochemistry: CYP8B1 Antibody (M15-P3B7) [NBP2-50218] - CYP8B1 normal colon mucosa Western Blot: CYP8B1 Antibody (M15-P3B7) [NBP2-50218] 0.1 mL Anmelden zum Anzeigen 7 bis 10 Tage
242,00 €
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Human Kaninchen Unkonjugiert FACS, IHC (p), WB Immunohistochemistry-Paraffin: CYP8B1 Antibody [NBP2-29939] - Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Western Blot: CYP8B1 Antibody [NBP2-29939] - Western blot analysis of (C-term) (NBP2-29939 ) in K562 cell line lysates (35ug/lane). CYP8B1 (arrow) was detected using the purified Pab. 0.4 mL Anmelden zum Anzeigen 5 bis 8 Tage
311,00 €
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Human Kaninchen Unkonjugiert WB Western Blot: CYP8B1 Antibody [NBP1-68884] - HepG2 cell lysate, concentration 0.2-1 ug/ml. 100 μL Anmelden zum Anzeigen 3 bis 6 Tage
341,00 €
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CYP8B1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Mouse (Murine)


Am meisten referenzierte anti-CYP8B1 Antikörper

  1. Human Polyclonal CYP8B1 Primary Antibody für IHC, ELISA - ABIN1452042 : Gåfvels, Olin, Chowdhary, Raudsepp, Andersson, Persson, Jansson, Björkhem, Eggertsen: Structure and chromosomal assignment of the sterol 12alpha-hydroxylase gene (CYP8B1) in human and mouse: eukaryotic cytochrome P-450 gene devoid of introns. in Genomics 1999 (PubMed)
    Zeige alle 2 Referenzen für 1452042

Weitere Antikörper gegen CYP8B1 Interaktionspartner

Human Cytochrome P450, Family 8, Subfamily B, Polypeptide 1 (CYP8B1) Interaktionspartner

  1. RORalpha is a key regulator of diurnal rhythm and fasting induction of CYP8B1, which regulates bile acid composition and serum and liver cholesterol levels.

  2. The single nucleotide polymorphism rs3732860 in the 3'-untranslated region of the CYP8B1 gene is associated with risk of Gallstone Disease in Chinese Han.

  3. SNP rs3732860 of CYP8B1 gene is associated with gallstone disease in this Chinese population.

  4. Cholesterol loading reduces SREBP-1 (zeige SREBF1 Antikörper) mRNA expression in addition to reducing functional SREBP-1 (zeige SREBF1 Antikörper) protein, and results in decreasing CYP8B1 gene transcription.

  5. Studies indicate a homogenous pattern for CYP8B1 expression in human liver, which was even rather than zonal.

  6. T(3) dose-dependently decreased total bile acid formation in parallel with decreased expression of CYP7A1 (zeige CYP7A1 Antikörper) and CYP8B1

  7. Isoflavone-related induction of 12-alpha-hydroxylase (CYP8B1) was studied in vitro and murine in vivo models.

Mouse (Murine) Cytochrome P450, Family 8, Subfamily B, Polypeptide 1 (CYP8B1) Interaktionspartner

  1. Absence of Cyp8b1 results in improved glucose tolerance, insulin (zeige INS Antikörper) sensitivity, and beta-cell function, mediated by absence of cholic acid in Cyp8b1(-/-) mice.

  2. Cholesterol lowering properties of oats involve increased production of bile acids via the classic pathway with up-regulation of CYP7A1 (zeige CYP7A1 Antikörper) and CYP8B1.

  3. RORalpha is a key regulator of diurnal rhythm and fasting induction of CYP8B1, which regulates bile acid composition and serum and liver cholesterol levels.

  4. Feedback regulation of the rate-limiting biosynthetic enzyme CYP7A1 (zeige CYP7A1 Antikörper) is lost in Cyp8b1(-/-) mice, causing expansion of the bile acid pool and alterations in cholesterol metabolism.

  5. In the intercross between C57BL/6J and CASA (zeige CSN1S1 Antikörper)/Rk mice, Cyp8b1 is not responsible for biliary bile acid composition.

  6. The expression pattern of Cyp8b1 was studied in hepatocytes.

  7. Isoflavone-related induction of 12-alpha-hydroxylase (CYP8B1) was studied in vitro and murine in vivo models.

CYP8B1 Antigen-Profil

Protein Überblick

Involved in bile acid synthesis and is responsible for the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7 alpha, 12 alpha-dihydroxy-4-cholesten-3-one. Responsible for the balance between formation of cholic acid and chenodeoxycholic acid. Has a rather broad substrate specificity including a number of 7-alpha- hydroxylated C27 steroids.

Genbezeichner und Symbole assoziert mit CYP8B1

  • cytochrome P450, family 8, subfamily b, polypeptide 1 (Cyp8b1) Antikörper
  • cytochrome P450, family 8, subfamily B, polypeptide 1 (cyp8b1) Antikörper
  • cytochrome P450, family 8, subfamily B, polypeptide 1 (CYP8B1) Antikörper
  • CP8B Antikörper
  • CYP8B Antikörper
  • CYP12 Antikörper
  • MGC64456 Antikörper

Bezeichner auf Proteinebene für CYP8B1

7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase , cytochrome P450 8b1 sterol 12 alpha-hydrolase , cytochrome P450, 8b1, sterol 12 alpha-hydrolase , cytochrome P450, family 8, subfamily B, polypeptide 1 , cytochrome P450, family 8, subfamily B , 7 alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase , 7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase , CYPVIIIB1 , cytochrome P450 8B1 , cytochrome P450, subfamily VIIIB (sterol 12-alpha-hydroxylase), polypeptide 1 , sterol 12-alpha-hydroxylase , sterol 12-alpha-hydrolase , sterol 12-alpha hydroxylase

GENE ID SPEZIES
81924 Rattus norvegicus
379482 Xenopus laevis
425055 Gallus gallus
538964 Bos taurus
1582 Homo sapiens
13124 Mus musculus
100009301 Oryctolagus cuniculus
Ausgewählte Anbieter für anti-CYP8B1 (CYP8B1) Antikörper
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