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CYP2W1 encodes a member of the cytochrome P450 superfamily of enzymes. Zusätzlich bieten wir Ihnen Cytochrome P450, Family 2, Subfamily W, Polypeptide 1 Antikörper (63) und viele weitere Produktgruppen zu diesem Protein an.
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summarizes the history, distribution, polymorphism, membrane topology, function and possible role in cancer therapy of CYP2W1.
Normal adrenal tissue lacks CYP2W1 enzyme expression; adrenocortical carcinomas generally do not express the enzyme as well.
Report novel SNPs of CYP2W1 gene in Chinese Uygur and Han populations.
Data suggest that canonical cytochrome P-450 reductants (cytochrome P450 reductase (zeige POR Proteine); cytochrome b5 (zeige CYB5A Proteine)) cannot serve as electron donors for CYP2W1, a colon tumor-specific enzyme; glycosylation of CYP2W1 at Asn177 is required for full catalytic activity.
Results show the developmental expression of CYP2W1 in the GI tract mediated by epigenetic modifications, its specific location, and regulation by anticancer drugs which can be considered as an adjuvant therapy of colon and hepatic cancers.
Low KRT13 (zeige KRT13 Proteine) mRNA expression is associated with oral squamous cell carcinoma.
CYP2W1 is highly expressed in both normal and neoplastic adrenal glands making it a promising tool for targeted therapy in ACC
High CYP2W1 expression is seen in 26% of primary colorectal tumors and in 48% of corresponding liver metastases.
CYP2W1 could play an important role in hepatocellular carcinoma (HCC (zeige FAM126A Proteine)) and might serve as a valuable prognostic marker and potential target for gene therapy in the treatment of HCC (zeige FAM126A Proteine).
No significant differences in the distribution of CYP2W1*1, CYP2W1*2 and CYP2W1*6 alleles were found between CRC (zeige CALR Proteine) patients and controls.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.
cytochrome P450, family 2, subfamily W, polypeptide 1
, cytochrome P450 2W1