anti-Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1) Antikörper

The protein encoded by CDK2AP1 is a specific CDK2-associated protein, which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. Zusätzlich bieten wir Ihnen Cyclin-Dependent Kinase 2 Associated Protein 1 Proteine (12) und Cyclin-Dependent Kinase 2 Associated Protein 1 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CDK2AP1 13445 O35207
CDK2AP1 8099 O14519
CDK2AP1 360804  
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen
  • orders@antikoerper-online.de

Top anti-Cyclin-Dependent Kinase 2 Associated Protein 1 Antikörper auf antikoerper-online.de

Showing 10 out of 54 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from HeLa cells, using CDKPA1 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Western Blot: DOC1 Antibody [NBP1-84064] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells).Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells) Western Blot: DOC1 Antibody [NBP1-84064] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$439.69
Details
Human Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 16 Days
$460.63
Details
Huhn Kaninchen Unkonjugiert WB Western blot analysis of CDK2AP1 expression in HUVEC (A), HeLa (B) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert WB Western Blot: DOC1 Antibody [NBP2-16208] - Sample (30 ug of whole cell lysate) A: HCT116 B: MCF-7 7. 5% SDS PAGE gel, diluted at 1:1000. 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage
$447.56
Details
Human Kaninchen Unkonjugiert IHC (p), ELISA, WB Human, Small Intestine: Formalin-Fixed Paraffin-Embedded (FFPE) 50 μL Anmelden zum Anzeigen 7 bis 9 Tage
$451.00
Details
Fledermaus Kaninchen Unkonjugiert WB   50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Maus Unkonjugiert DB, ICC Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.01% Triton-X100 in PBS. The cells were immunostained with anti-CDK2AP1 antibody. Left: CDK2AP1 staining. Right: Coomassie Blue staining of immunized recombinant protein. 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$285.71
Details

CDK2AP1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Mouse (Murine)


Human , ,
,
,
, ,
Rat (Rattus)


Am meisten referenzierte anti-Cyclin-Dependent Kinase 2 Associated Protein 1 Antikörper

  1. Human Polyclonal CDK2AP1 Primary Antibody für IHC, IHC (p) - ABIN4305761 : Dieterich, Mellberg, Langenkamp, Zhang, Zieba, Salomäki, Teichert, Huang, Edqvist, Kraus, Augustin, Olofsson, Larsson, Söderberg, Molema, Pontén, Georgii-Hemming, Alafuzoff, Dimberg: Transcriptional profiling of human glioblastoma vessels indicates a key role of VEGF-A and TGFβ2 in vascular abnormalization. in The Journal of pathology 2012 (PubMed)

Weitere Antikörper gegen Cyclin-Dependent Kinase 2 Associated Protein 1 Interaktionspartner

Mouse (Murine) Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1) Interaktionspartner

  1. Cdk2ap1 expression is primarily regulated by progesterone and the progesterone receptor (zeige PGR Antikörper) in uterus and is mainly localized to proliferating tissues.

  2. Results indicate that DOC-1 (zeige CA6 Antikörper) is a bona fide subunit of the Mi-2 (zeige CHD4 Antikörper)/NuRD chromatin remodeling complex.

  3. (CDK2 (zeige CDK2 Antikörper)-AP1 (zeige JUN Antikörper)) is a potential gene therapeutic agent for oral/head and neck cancer in conjunction with DNA-damaging agents such as cisplatin.

  4. p12CDK2-AP1 (zeige JUN Antikörper) forms nuclear homodimers in contact inhibited normal diploid cells and dimerization of p12 is a necessary process for the growth inhibition effect by p12

  5. Results suggest that overexpression of CDK2 (zeige CDK2 Antikörper)-associating protein 1 (p12CDK2AP1) leads to testicular and ovarian abnormalities, a phenotype closely related to that of cdk2 (zeige CDK2 Antikörper)-/- mice.

  6. Cdk2ap1, a negative regulator of Cdk2 (zeige CDK2 Antikörper) function and cell cycle, promotes Oct4 (zeige POU5F1 Antikörper) promoter methylation during murine embryonic stem cell differentiation to down-regulate Oct4 (zeige POU5F1 Antikörper) expression.

  7. Cdk2ap1 plays an essential role in the early stage of embryogenesis and has a potential role during craniofacial morphogenesis.

  8. CDK2AP1-mediated differentiation of murine embryonic stem cell was elicited through the regulation of pRb (zeige PGR Antikörper).

Human Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1) Interaktionspartner

  1. The simultaneous overexpression of p12CDK2-AP1 (zeige FOSB Antikörper) and CD82 (zeige CD82 Antikörper) significantly suppressed the in vivo tumor growth.

  2. knockdown of CDK2AP1 in primary human fibroblasts reduced proliferation and induced premature senescence, with the observed phenotype being p53 (zeige TP53 Antikörper) dependent

  3. In summary, p12CDK2AP1 expression in myxofibrosarcoma cells induces G0/G1 arrest and mitochondria dependent proapoptotic activity and down-regulation of p12CDK2AP1 by shRNAi results in up-regulation of the CDK2 (zeige CDK2 Antikörper) transcript and protein.

  4. Study reports that knockdown of CDK2AP1 by RNAi in glioma cells could effectively inhibit cell proliferation by inducing cell cycle arrest and apoptosis

  5. CDK2AP1 plays an important role in modulating the growth and tumorigenesis of lung cancer cells.

  6. Low CDK2AP1 expression is common and associated with adverse prognosis in nasopharyngeal carcinoma.

  7. Human cyclin-dependent kinase 2-associated protein 1 (CDK2AP1) is dimeric in its disulfide-reduced state, with natively disordered N-terminal region

  8. In comparison with the healthy gingiva, the expression of Doc-1 was decreased, whereas the expression of S100A7 (zeige S100A7 Antikörper) was upregulated in all oral lesions.

  9. P12(CDK2AP1) is downregulated by miR (zeige MLXIP Antikörper)-21

  10. Missing down-regulation of the tumor-suppressor gene DOC-1, might exert protective effects and counteract malignant transformation of benign, proliferating lesions of the oral cavity.

Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1) Antigen-Profil

Protein Überblick

The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Genbezeichner und Symbole assoziert mit CDK2AP1

  • cyclin-dependent kinase 2 associated protein 1 S homeolog (cdk2ap1.S) Antikörper
  • cyclin dependent kinase 2 associated protein 1 (CDK2AP1) Antikörper
  • cyclin dependent kinase 2 associated protein 1 pseudogene (LOC475806) Antikörper
  • cyclin-dependent kinase 2 associated protein 1 (cdk2ap1) Antikörper
  • CDK2 (cyclin-dependent kinase 2)-associated protein 1 (Cdk2ap1) Antikörper
  • cyclin-dependent kinase 2 associated protein 1 (Cdk2ap1) Antikörper
  • cyclin dependent kinase 2 associated protein 1 (Cdk2ap1) Antikörper
  • Apc10 Antikörper
  • Cdkap1 Antikörper
  • doc-1 Antikörper
  • DOC1 Antikörper
  • DORC1 Antikörper
  • MGC64532 Antikörper
  • p12 Antikörper
  • p12DOC-1 Antikörper
  • ST19 Antikörper

Bezeichner auf Proteinebene für CDK2AP1

cyclin-dependent kinase 2 associated protein 1 , CDK2-associated protein 1 , CDK2 (cyclin-dependent kinase 2)-associated protein 1 , cyclin-dependent kinase 2-associated protein 1 , CDK2-associated protein1 , deleted in oral cancer 1 , putative oral cancer suppressor , Deleted in oral cancer-1

GENE ID SPEZIES
380551 Xenopus laevis
452342 Pan troglodytes
475806 Canis lupus familiaris
549484 Xenopus (Silurana) tropicalis
615387 Bos taurus
704412 Macaca mulatta
100153712 Sus scrofa
13445 Mus musculus
8099 Homo sapiens
360804 Rattus norvegicus
101825251 Mesocricetus auratus
Ausgewählte Anbieter für anti-Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1) Antikörper
Haben Sie etwas anderes gesucht?