Core 1 Synthase, Glycoprotein-N-Acetylgalactosamine 3-beta-Galactosyltransferase, 1 (C1GALT1) ELISA Kits

The protein encoded by C1GALT1 generates the common core 1 O-glycan structure, Gal-beta-1-3GalNAc-R, by the transfer of Gal from UDP-Gal to GalNAc-alpha-1-R. Zusätzlich bieten wir Ihnen Core 1 Synthase, Glycoprotein-N-Acetylgalactosamine 3-beta-Galactosyltransferase, 1 Antikörper (29) und Core 1 Synthase, Glycoprotein-N-Acetylgalactosamine 3-beta-Galactosyltransferase, 1 Proteine (9) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
C1GALT1 56913 Q9NS00
C1GALT1 94192 Q9JJ06
C1GALT1 65044 Q9JJ05
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Weitere ELISA Kits für Core 1 Synthase, Glycoprotein-N-Acetylgalactosamine 3-beta-Galactosyltransferase, 1 Interaktionspartner

Human Core 1 Synthase, Glycoprotein-N-Acetylgalactosamine 3-beta-Galactosyltransferase, 1 (C1GALT1) Interaktionspartner

  1. These findings demonstrate that common variation at C1GALT1 influences Gd-IgA1 level in the population, which independently associates with risk of progressive IgA nephropathy, and that the pathogenic importance of changes in IgA1 O-glycosylation may vary between white and Chinese patients with IgA nephropathy

  2. Polymorphisms near C1galt1 (rs10486157) and its molecular chaperone, Cosmc (rs4825729), were associated with altered composition of (zeige SLC13A2 ELISA Kits) the colonic mucosal microbiota in Crohn's disease patients.

  3. Data indicate that mRNA levels of both core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase (zeige GGTA1 ELISA Kits), 1 (C1GALT1) and C1GALT1-specific chaperone 1 (zeige C1GALT1C1 ELISA Kits) protein (C1GALT1C1 (zeige C1GALT1C1 ELISA Kits)) determine the rate of secretion of galactose-deficient IgA1 (Gd-IgA1) in IgA1-producing cells.

  4. The terminal glycosylation of secreted IgA1 was altered in response to TGFbeta1 (zeige TGFB1 ELISA Kits). TGFbeta1 (zeige TGFB1 ELISA Kits) stimulation significantly decreased the mRNA levels of C1GalT1 and Cosmc (zeige C1GALT1C1 ELISA Kits). TGFbeta1 (zeige TGFB1 ELISA Kits) may be key in controlling the glycosylation of IgA1, in part via the downregulation of C1GalT1 and Cosmc (zeige C1GALT1C1 ELISA Kits).

  5. There was no statistically significant difference between the two groups (P > 0.05). The rs1047763 SNP of the C1GALT1 gene probably has no correlation with genetic susceptibility to IgAN in Xinjiang Uyghur people.

  6. Polymorphisms in the C1GALT1 gene were associated with genetic susceptibility to Uyghur Immunoglobulin A (IgA) nephropathy.

  7. Overexpression of C1GALT1 enhanced breast cancer cell growth, migration, and invasion in vitro as well as tumor growth in vivo.

  8. C1GALT1 promotes invasive phenotypes of hepatocellular carcinoma cells by modulating integrin beta1 glycosylation and activity.

  9. Cosmc (zeige C1GALT1C1 ELISA Kits) and T-synthase are transcriptionally regulated at a basal level by the specificity protein/Kruppel-like transcription factor (zeige KLF4 ELISA Kits) family of members.

  10. Using qRT-PCR, sialyl-Tn expression was found to be associated with an increase in alpha2,6-sialyltransferase gene (ST6GALNAC1) and a decrease in core 1 synthase gene (C1GALT1) in LS174T cells.

Mouse (Murine) Core 1 Synthase, Glycoprotein-N-Acetylgalactosamine 3-beta-Galactosyltransferase, 1 (C1GALT1) Interaktionspartner

  1. Deletion of C1galt1 in mice develop spontaneous microbiota-dependent colitis with a remitting/relapsing course due to loss of mucin (zeige SLC13A2 ELISA Kits) core-1 derived O-glycans.

  2. C1GALT1 promotes invasive phenotypes of hepatocellular carcinoma cells by modulating integrin beta1 glycosylation and activity.

  3. O-glycan is required for terminal megakaryocyte differentiation and platelet production and the decrease in GPIbalpha (zeige GP1BA ELISA Kits) in cells lacking O-glycan might be caused by increased proteolysis.

  4. Data from transgenic mice suggest that a lack of complex N- and O-glycans impairs early embryo development and viability in vivo leading to delayed implantation and embryo loss; C1galt1 and MGAT1 (zeige MGAT1 ELISA Kits) are required for embryo development and implantation.

  5. disease in plt1/plt1 mice suggests that, in addition to immune-mediated effects, intrinsic C1Gal-T1 deficiency in megakaryocytes and the kidney may contribute to pathology

  6. Transgenic mice were generated lacking T-synthase (C1galt1).

Core 1 Synthase, Glycoprotein-N-Acetylgalactosamine 3-beta-Galactosyltransferase, 1 (C1GALT1) Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene generates the common core 1 O-glycan structure, Gal-beta-1-3GalNAc-R, by the transfer of Gal from UDP-Gal to GalNAc-alpha-1-R. Core 1 is a precursor for many extended mucin-type O-glycans on cell surface and secreted glycoproteins. Studies in mice suggest that this gene plays a key role in thrombopoiesis and kidney homeostasis.

Genbezeichner und Symbole assoziert mit C1GALT1

  • core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1 (C1GALT1) Antikörper
  • core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1b (c1galt1b) Antikörper
  • core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1 (C1galt1) Antikörper
  • glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 (c1galt1) Antikörper
  • 2210410E06Rik Antikörper
  • AV284120 Antikörper
  • C1GALT Antikörper
  • C1GALT1 Antikörper
  • fa98f05 Antikörper
  • T-synthase Antikörper
  • wu:fa98f05 Antikörper
  • zgc:66485 Antikörper

Bezeichner auf Proteinebene für C1GALT1

C1GalT1-B , core 1 O-glycan T-synthase B , core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1-B , core 1 beta1,3-galactosyltransferase 1-B , core 1 beta3-Gal-T-B , core 1 beta3-Gal-T1-B , core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1 , core1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1-B , glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1-B , glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1-like , B3Gal-T8 , core 1 O-glycan T-synthase , core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1 , core 1 beta3-Gal-T1 , glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 , T-syn , core 1 beta1,3-galactosyltransferase 1 , core 1 beta3-Gal-T , core1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1 , core1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase (C1galt1) , core1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 13-galactosyltransferase (C1galt1) , core1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galac

GENE ID SPEZIES
482314 Canis lupus familiaris
337131 Danio rerio
472288 Pan troglodytes
100406487 Callithrix jacchus
100483848 Ailuropoda melanoleuca
56913 Homo sapiens
94192 Mus musculus
65044 Rattus norvegicus
539417 Bos taurus
420575 Gallus gallus
444326 Xenopus laevis
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