Chromosome 13 Open Reading Frame 15 (C13orf15) ELISA Kits

C13orf15 is thought to regulate cell cycle progression. Zusätzlich bieten wir Ihnen Chromosome 13 Open Reading Frame 15 Antikörper (23) und Chromosome 13 Open Reading Frame 15 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
C13orf15 28984 Q9H4X1
Anti-Maus C13orf15 C13orf15 66214 Q9DBX1
Anti-Ratte C13orf15 C13orf15 117183 Q9Z2P4
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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.128 ng/mL 0.31-20 ng/mL 96 Tests Anmelden zum Anzeigen 11 bis 15 Tage
651,85 €
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Weitere ELISA Kits für Chromosome 13 Open Reading Frame 15 Interaktionspartner

Human Chromosome 13 Open Reading Frame 15 (C13orf15) Interaktionspartner

  1. RGC-32 mediates human aortic endothelial cell migration through the regulation of RhoA (zeige RHOA ELISA Kits) and ROCK1 (zeige ROCK1 ELISA Kits) expression.

  2. RGCC may be a candidate cell cycle target for neuroprotection during the onset of Alzheimer's disease.

  3. RGC-32 expression on M2-polarized and tumor-associated macrophages is M-CSF (zeige CSF1 ELISA Kits)-dependent and enhanced by tumor-derived IL-4 (zeige IL4 ELISA Kits).

  4. Data suggest that expression of RGC32 is down-regulated in placental trophoblasts in women with pre-eclampsia as compared to women with normal term pregnancies; silencing RGC32 expression by RNA interference inhibits trophoblast migration/invasion.

  5. Suggest that RGC32 is involved in tumorigenesis of human lung cancer, inducing apoptosis and inhibiting cell growth, migration, and invasion.

  6. In conclusion, the present study indicates that C5a may promote the proliferation of breast cancer cells through Akt1 (zeige AKT1 ELISA Kits) activation of the RGC-32 gene.

  7. results demonstrate for the first time that RGC-32 is a novel membrane regulator for macrophage phagocytosis.

  8. RGC32 promotes cell migration and invasion and induces epithelial-mesenchymal transition in lung cancer cells via the NF-kappaB (zeige NFKB1 ELISA Kits) signaling pathway.

  9. data suggest RGC-32 plays a dual role in multiple sclerosis, both as a regulator of T-cells mediated apoptosis and as a promoter of TGF-beta (zeige TGFB1 ELISA Kits)-mediated profibrotic effects in astrocytes

  10. analysis of upregulation of the cell-cycle regulator RGC-32 in Epstein-Barr virus-immortalized cells, due to transcriptional activation by high levels of the differentially expressed RUNX1c transcription factor

Mouse (Murine) Chromosome 13 Open Reading Frame 15 (C13orf15) Interaktionspartner

  1. results identify RGC-32 as a novel regulator of Th17 cell differentiation in vitro and in vivo and suggest that RGC-32 is a potential therapeutic target in multiple sclerosis and other Th17-mediated autoimmune diseases

  2. results demonstrate that RGC-32 contributes to the development of hepatic steatosis by facilitating de novo lipogenesis through activating liver X receptor, leading to the induction of SREBP-1c (zeige SREBF1 ELISA Kits) and its target genes

  3. RGC-32 is involved in controlling the cell cycle of T cells in vivo, and this effect is mediated by IL-2 (zeige IL2 ELISA Kits) in a PI3K-dependent fashion.

  4. RGC32 plays an important role in diet-induced obesity and insulin (zeige INS ELISA Kits) resistance, and thus it may serve as a potential novel drug target for developing therapeutics to treat obesity and metabolic disorders.

  5. results demonstrate for the first time that RGC-32 is a novel membrane regulator for macrophage phagocytosis.

  6. knockdown of RGC-32 by shRNA inhibited VEGF (zeige VEGFA ELISA Kits)-induced endothelial cell proliferation, migration, and tube formation while blocking VEGFR2 (zeige KDR ELISA Kits) expression.

  7. RGC-32 as a novel fibrogenic factor contributing to the pathogenesis of renal fibrosis through fibroblast activation.

  8. Smad2 (zeige SMAD2 ELISA Kits) and PEA3 (zeige ETV4 ELISA Kits) regulate RGC-32 transcription which is essential for smooth muscle cell differentiation from neural crest cells.

Chromosome 13 Open Reading Frame 15 (C13orf15) Antigen-Profil

Beschreibung des Gens

This gene is thought to regulate cell cycle progression. It is induced by p53 in response to DNA damage, or by sublytic levels of complement system proteins that result in activation of the cell cycle. The encoded protein localizes to the cytoplasm during interphase and to centrosomes during mitosis. The protein forms a complex with polo-like kinase 1. The protein also translocates to the nucleus in response to treatment with complement system proteins, and can associate with and increase the kinase activity of cell division cycle 2 protein. In different assays and cell types, overexpression of this protein has been shown to activate or suppress cell cycle progression.

Genbezeichner und Symbole assoziert mit C13orf15

  • regulator of cell cycle (RGCC) Antikörper
  • regulator of cell cycle (Rgcc) Antikörper
  • response gene to complement 32 protein (RGC32) Antikörper
  • similar to response gene to complement 32 (LOC683573) Antikörper
  • 1190002H23Rik Antikörper
  • bA157L14.2 Antikörper
  • C13orf15 Antikörper
  • Rgc-32 Antikörper
  • Rgc32 Antikörper

Bezeichner auf Proteinebene für C13orf15

regulator of cell cycle RGCC , response gene to complement 32 protein , RGC-32

GENE ID SPEZIES
28984 Homo sapiens
66214 Mus musculus
117183 Rattus norvegicus
100625944 Sus scrofa
683573 Rattus norvegicus
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