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The product of CKLF is a cytokine. Zusätzlich bieten wir Ihnen CKLF Kits (26) und und viele weitere Produktgruppen zu diesem Protein an.
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CKLF1 expression was up-regulated in synovim from rheumatoid arthritis and ankylosing spondylitis patients.
Chemokine-like factor 1 is over-expressed in patients with atopic dermatitis.
CKLF1 can induce proliferation and inhibit apoptosis of human vascular smooth muscle cell through the down-regulation of Bax (zeige BAX Antikörper) and Caspase-3 (zeige CASP3 Antikörper) and the up-regulation of Bcl-2 (zeige BCL2 Antikörper) expression.
The expression of CKLF1 is up-regulated in atherosclerotic plaques.
CKLF1-C19 and -C27 can stimulate antigen-presenting capability of dendritic cells
CKLF1 could increase the proliferation of human bone marrow hematopoietic progenitor cells and colony formation
Results confirm that the secreted peptides of CKLF1, C27 and C19, have functional activation via CCR4 (zeige CCR4 Antikörper).
Chemokine-like factor expression is differentially regulated in myoblasts and myotubes and thrombin (zeige F2 Antikörper) could be a strong regulator for its expression
NF-kappaB (zeige NFKB1 Antikörper) signaling pathway was involved in the asthmatic change induced by CKLF1, among which CCR4 (zeige CCR4 Antikörper) might play a crucial role
The product of this gene is a cytokine. Cytokines are small proteins that have an essential role in the immune and inflammatory responses. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 16. The protein encoded by this gene is a potent chemoattractant for neutrophils, monocytes and lymphocytes. It also can stimulate the proliferation of skeletal muscle cells. This protein may play important roles in inflammation and in the regeneration of skeletal muscle. Alternatively spliced transcript variants encoding different isoforms have been identified. Naturally occurring read-through transcription occurs between this locus and the neighboring locus CMTM1 (CKLF-like MARVEL transmembrane domain containing 1).
chemokine-like factor 1
, chemokine-like factor 2
, chemokine-like factor 3
, chemokine-like factor 4
, transmembrane proteolipid
, chemokine-like factor 6