Cation Channel, Sperm Associated 4 Proteine (CATSPER4)

Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. Zusätzlich bieten wir Ihnen Cation Channel, Sperm Associated 4 Antikörper (19) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Ratte CATSPER4 CATSPER4 362623  
CATSPER4 378807 Q7RTX7
CATSPER4 329954 Q8BVN3
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Showing 4 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 46 bis 51 Tage
5.743,80 €
Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 46 bis 51 Tage
4.032,65 €
Details
HOST_Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
Details

CATSPER4 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine) ,
,

Weitere Proteine zu Cation Channel, Sperm Associated 4 (CATSPER4) Interaktionspartnern

Human Cation Channel, Sperm Associated 4 (CATSPER4) Interaktionspartner

  1. Catsper4 has a single channel-forming domain, a pore-loop with the consensus sequence TxDxW, & a coiled-coil protein-protein interaction domain in the C-terminal tail. CatSpers 1,2,3 & 4 may interact directly or indirectly to form a functional tetramer.

Mouse (Murine) Cation Channel, Sperm Associated 4 (CATSPER4) Interaktionspartner

  1. Catsper4 has a single channel-forming domain, a pore-loop with the consensus sequence TxDxW, & a coiled-coil protein-protein interaction domain in the C-terminal tail. CatSpers 1,2,3 & 4 may interact directly or indirectly to form a functional tetramer.

  2. CATSPER4 is a cation-channel (zeige TRPV1 Proteine) protein and has role in acrosome reaction and male fertility

  3. Catsper3 (zeige CATSPER3 Proteine) and Catsper4 knockout male mice are completely infertile due to a quick loss of motility and a lack of hyperactivated motility under capacitating conditions.

Cation Channel, Sperm Associated 4 (CATSPER4) Protein Überblick

Protein Überblick

Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. Activated by extracellular progesterone and prostaglandins following the The primary effect of progesterone activation is to shift voltage dependence towards more physiological, negative membrane potentials\; it is not mediated by metabotropic receptors and second messengers. Sperm capacitation enhances the effect of progesterone by providing additional negative shift. Also activated by the elevation of intracellular pH.

Genbezeichner und Symbole assoziert mit CATSPER4

  • cation channel, sperm associated 4 (Catsper4)
  • cation channel, sperm associated 4 (CATSPER4)
  • cation channel, sperm associated 4 (LOC100345860)
  • 4933412L05 Protein
  • RGD1565213 Protein

Bezeichner auf Proteinebene für CATSPER4

channel, sperm associated 4 , cation channel, sperm associated 4 , cation channel sperm-associated protein 4 , ion channel CatSper4 , cation channel of sperm 4

GENE ID SPEZIES
362623 Rattus norvegicus
487358 Canis lupus familiaris
520788 Bos taurus
714205 Macaca mulatta
736458 Pan troglodytes
100345860 Oryctolagus cuniculus
100414658 Callithrix jacchus
100461679 Pongo abelii
100600401 Nomascus leucogenys
378807 Homo sapiens
329954 Mus musculus
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