Cadherin EGF LAG Seven Pass G-Type Receptor 3 Proteine (CELSR3)

The protein encoded by CELSR3 is a member of the flamingo subfamily, part of the cadherin superfamily. Zusätzlich bieten wir Ihnen CELSR3 Antikörper (80) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
CELSR3 1951 Q9NYQ7
Ratte CELSR3 CELSR3 83466 O88278
CELSR3 107934 Q91ZI0
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Showing 5 out of 5 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
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Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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HOST_Escherichia coli (E. coli) Human T7 tag,His tag   100 μg Anmelden zum Anzeigen 13 bis 17 Tage
640,00 €
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HOST_Escherichia coli (E. coli) Maus T7 tag,His tag   100 μg Anmelden zum Anzeigen 13 bis 17 Tage
670,48 €
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CELSR3 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine) ,
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Weitere Proteine zu Cadherin EGF LAG Seven Pass G-Type Receptor 3 (CELSR3) Interaktionspartnern

Human Cadherin EGF LAG Seven Pass G-Type Receptor 3 (CELSR3) Interaktionspartner

  1. Study identifies four likely Tourette disorder risk genes with multiple de novo damaging variants in unrelated probands: WWC1 (WW and C2 domain containing 1 (zeige WWC1 Proteine)), CELSR3 (Cadherin EGF LAG seven-pass G-type receptor 3), NIPBL (zeige NIPBL Proteine) (Nipped (zeige RPL38 Proteine)-B-like), and FN1 (fibronectin 1 (zeige FN1 Proteine)).

  2. marked reduction in the prominence of TUJ1 bundles in number, thickness, and length. Our results showed that deregulation of the planar cell polarity genes CELSR3 and FZD3 (zeige FZD3 Proteine) might disrupt the enteric innervation pattern

  3. A moderate positive correlation between CELSR3 and patient age was also evident.

  4. seven-transmembrane domain receptors Celsr3 and Fzd3 (zeige FZD3 Proteine), in particular, control the development of most longitudinal tracts in the central nervous system. [Review]

  5. CELSR3 promoter hypermethylation is associated with oral squamous cell carcinoma.

  6. CELSR3 was found to be selectively up-regulated in tumor stellate cells.

  7. CELSR3 is one of the core PCP (zeige PRCP Proteine) signaling molecules.

Mouse (Murine) Cadherin EGF LAG Seven Pass G-Type Receptor 3 (CELSR3) Interaktionspartner

  1. Celsr3 and Fzd3 (zeige FZD3 Proteine) enable immature neurons to respond to Wnt7 (zeige WNT7B Proteine), upregulate Jag1 (zeige JAG1 Proteine) and thereby facilitate feedback signals that tune the timing of neural progenitor cell fate decisions via Notch (zeige NOTCH1 Proteine) activation.

  2. Our results provide evidence that the Celsr3-Fzd3 (zeige FZD3 Proteine) pathway interacts with EphA-ephrinA reverse signaling to guide motor axons in the hindlimb.

  3. The essential role of Celsr3 in globus pallidus development.

  4. The first signal, controlled by cadherin, EGF (zeige EGF Proteine)-like, laminin G-like, seven-pass, G-type receptor (Celsr) 2 (zeige CELSR2 Proteine), Celsr3, Frizzled3 (Fzd3 (zeige FZD3 Proteine)) and Van Gogh (zeige VANGL2 Proteine) like2 (Vangl2 (zeige VANGL2 Proteine)) organizes multicilia in individual cells (single-cell polarity)

  5. Celsr2 (zeige CELSR2 Proteine)-3 and Fzd3 (zeige FZD3 Proteine) regulate axonal navigation in the forebrain by using mechanisms different from classical epithelial core planar cell polarity, and require interacting partners other than Vangl1 (zeige Vangl1 Proteine)-2 that remain to be identified.

  6. This study demonistrated that Celsr3/Foxg1 (zeige FOXG1 Proteine) mutation mice show the spinal motor network does not mature fully in the absence of corticofugal connections, and that some motor function is preserved despite congenital absence of the corticospinal tract.

  7. Celsr3 and Fzd3 (zeige FZD3 Proteine) are required during murine embryogenesis to specifically control the guidance and growth of enteric neuronal projections relative to the longitudinal and radial gut (zeige GUSB Proteine) axes.

  8. Celsr3/Foxg1 & Celsr3/Dlx mutant mice were hyperactive, learning- & memory-impaired. Celsr3/Foxg1 caused abnormal cytoarchitecture of CA1, CA3, & dentate gyrus. Celsr3|Dlx mildly affected hippocampal and extrinsic & intrinsic connectivity.

  9. Celsr2 (zeige CELSR2 Proteine) and Celsr3 control the development and function of ependymal cilia; findings suggest that planar cell polarity signaling is involved in ependymal cilia development and in the pathophysiology of hydrocephalus, and possibly other ciliopathies

  10. Developmental expression profiles of Celsr (Flamingo (zeige CELSR2 Proteine)) genes in the mouse

CELSR3 Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins\; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined.

Genbezeichner und Symbole assoziert mit CELSR3

  • cadherin, EGF LAG seven-pass G-type receptor 3 (CELSR3)
  • cadherin, EGF LAG seven-pass G-type receptor 3 (Celsr3)
  • cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila) (Celsr3)
  • CDHF11 Protein
  • EGFL1 Protein
  • flamingo Protein
  • Fmi1 Protein
  • HFMI1 Protein
  • Megf2 Protein
  • mKIAA0812 Protein
  • RESDA1 Protein

Bezeichner auf Proteinebene für CELSR3

EGF-like protein 1 , EGF-like-domain, multiple 1 , anchor protein , cadherin EGF LAG seven-pass G-type receptor 3 , cadherin family member 11 , cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila) , epidermal growth factor-like protein 1 , flamingo homolog 1 , multiple EGF-like domains protein 2 , multiple epidermal growth factor-like domains protein 2 , multiple epidermal growth factor-like domains 2

GENE ID SPEZIES
1951 Homo sapiens
83466 Rattus norvegicus
107934 Mus musculus
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