C-Type Lectin Domain Family 4, Member D Proteine (CLEC4D)

CLEC4D encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Zusätzlich bieten wir Ihnen CLEC4D Antikörper (66) und CLEC4D Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
CLEC4D 338339 Q8WXI8
CLEC4D 17474 Q9Z2H6
CLEC4D 362432 Q69FH1
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Showing 7 out of 10 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Human Cells Human His tag 100 μg Anmelden zum Anzeigen 18 bis 20 Tage
525,00 €
Details
HOST_Human Cells Ratte His tag 100 μg Anmelden zum Anzeigen 18 bis 20 Tage
525,00 €
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 46 bis 51 Tage
4.032,65 €
Details
HOST_Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 7 bis 8 Tage
235,20 €
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
Details
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.282,07 €
Details

CLEC4D Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, , ,
Mouse (Murine)
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Rat (Rattus) ,
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Am meisten referenzierte CLEC4D Proteine

  1. Human CLEC4D Protein expressed in Human Cells - ABIN2004304 : Zelensky, Gready: The C-type lectin-like domain superfamily. in The FEBS journal 2005 (PubMed)
    Zeige alle 2 Referenzen für 2004304

  2. Rat (Rattus) CLEC4D Protein expressed in Human Cells - ABIN2009320 : Cambi, Figdor: Necrosis: C-type lectins sense cell death. in Current biology : CB 2009 (PubMed)
    Zeige alle 2 Referenzen für 2009320

Weitere Proteine zu C-Type Lectin Domain Family 4, Member D (CLEC4D) Interaktionspartnern

Human C-Type Lectin Domain Family 4, Member D (CLEC4D) Interaktionspartner

  1. Results show the molecular mechanism of glycolipid recognition through C-type lectin (zeige MBL2 Proteine) receptors, which may provide clues to rational design for effective adjuvants.

  2. CLECSF8 functions as an activation receptor on myeloid cells and associates with a novel adaptor molecule

  3. Cross-linking of the receptor leads to a rapid internalization suggesting that CLECSF8 constitutes and endocytic receptor.

Mouse (Murine) C-Type Lectin Domain Family 4, Member D (CLEC4D) Interaktionspartner

  1. activation of CLRs Dectin-2 (zeige CLEC6A Proteine) and Dectin-3 by fungi infections triggers them for ubiquitination and degradation in a Syk (zeige SYK Proteine)-dependent manner.

  2. The authors report that microbial stimulation triggers Mincle (Clec4e (zeige CLEC4E Proteine)) expression through the myeloid differentiation primary response gene 88 (MyD88 (zeige MYD88 Proteine)) pathway; a process that does not require MCL (Clecsf8, Clec4d). Conversely, they show that MCL is constitutively expressed but retained intracellularly until Mincle (zeige CLEC4E Proteine) is induced, whereupon the receptors form heterodimers which are translocated to the cell surface.

  3. Data show that Mincle (zeige CLEC4E Proteine), the inducible receptor for mycobacterial cord factor, is the key switch for the transition of macrophages from cytokine expression to high nitric oxide production.

  4. MCL regulates the development of vaccine-induced Th17 cells and protective immunity against lethal experimental infection with Blastomyces dermatitidis.

  5. major contributor to activation of innate immunity against M. bovis in experimental model, mirrors Mincle (zeige CLEC4E Proteine) expression

  6. Clecsf8-/- mice exhibit higher bacterial burdens and increased mortality upon Mycobacterium tuberculosis infection.

  7. These results suggest that MCL positively regulates Mincle (zeige CLEC4E Proteine) expression through protein-protein interaction via its stalk region, thereby magnifying Mincle (zeige CLEC4E Proteine)-mediated signaling.

  8. Trehalose 6,6'-dimycolate-induced Mincle (zeige CLEC4E Proteine) expression is dependent on Dectin-3-mediated NF-kappaB (zeige NFKB1 Proteine) activation through the CARD9 (zeige CARD9 Proteine)-BCL10 (zeige BCL10 Proteine)-MALT1 (zeige MALT1 Proteine) complex.

  9. Compared to their respective homodimers, Dectin-3 and Dectin-2 (zeige CLEC6A Proteine) heterodimers bound alpha-mannans more effectively, leading to potent inflammatory responses against fungal infections.

  10. Clec4d(-/-) neutrophils did not exhibit any defect in bacterial clearance

CLEC4D Protein Überblick

Protein Überblick

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

Genbezeichner und Symbole assoziert mit CLEC4D

  • C-type lectin domain family 4, member D (CLEC4D)
  • C-type lectin domain family 4, member d (Clec4d)
  • C-type lectin domain family 4, member D (Clec4d)
  • CLEC-6 Protein
  • CLEC4D Protein
  • CLEC6 Protein
  • Clecsf8 Protein
  • Mcl Protein
  • Mpcl Protein

Bezeichner auf Proteinebene für CLEC4D

C-type lectin domain family 4, member D , C-type lectin domain family 4 member D , C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 8 , C-type lectin receptor , C-type lectin superfamily member 8 , C-type lectin-like receptor 6 , macrophage C-type lectin , C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 8 , C-type lectin, superfamily member 8 , macrophage-restricted C-type lectin

GENE ID SPEZIES
473405 Pan troglodytes
611536 Canis lupus familiaris
616646 Bos taurus
338339 Homo sapiens
17474 Mus musculus
362432 Rattus norvegicus
Ausgewählte Anbieter für CLEC4D Proteine (CLEC4D)
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