C-Type Lectin Domain Family 14, Member A Proteine (CLEC14A)

CLEC14A encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Zusätzlich bieten wir Ihnen CLEC14A Antikörper (64) und CLEC14A Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
CLEC14A 161198 Q86T13
CLEC14A 66864 Q8VCP9
CLEC14A    
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Top CLEC14A Proteine auf antikoerper-online.de

Showing 5 out of 7 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
$4,244.78
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,442.50
Details
Human Cells Maus His tag 50 μg Anmelden zum Anzeigen 20 bis 21 Tage
$382.80
Details
Human Cells Ratte Fc Tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$437.80
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$405.71
Details

CLEC14A Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
, ,
Mouse (Murine) ,
,
Rat (Rattus)

Weitere Proteine zu C-Type Lectin Domain Family 14, Member A (CLEC14A) Interaktionspartnern

Human C-Type Lectin Domain Family 14, Member A (CLEC14A) Interaktionspartner

  1. These findings identify novel protein interactions involving CLEC14A, CD93 (zeige CD93 Proteine) and CD248 (zeige CD248 Proteine) with MMRN2 (zeige MMRN2 Proteine) as targetable components of vessel formation

  2. The CLEC14A-MMRN2 (zeige MMRN2 Proteine) interaction is involved in sprouting angiogenesis. Disrupting this interaction with monoclonal antibodies directed against CLEC14A show anti-angiogenic and anti-tumor effects.

  3. CLEC14A is a matrix component which binds to MMRN2 (zeige MMRN2 Proteine) in the process of endothelial cells transformation in tumor angiogenesis.

  4. clec14a-CTLD may be a key domain in angiogenesis

  5. In this study, they identify and characterize a novel tumor endothelial marker, CLEC14A, which has properties that suggest it is a candidate for tumor vascular targeting and anti-angiogenic approaches.

Mouse (Murine) C-Type Lectin Domain Family 14, Member A (CLEC14A) Interaktionspartner

  1. CLEC14A acts in vascular homeostasis by fine-tuning VEGFR-2 (zeige KDR Proteine) and VEGFR-3 (zeige FLT4 Proteine) signaling in endothelial cells

  2. clec14a-CTLD may be a key domain in angiogenesis

  3. These findings demonstrate that Clec14a is a novel endothelial cells specific protein that appears to play a role in cell-cell adhesion and angiogenesis.

CLEC14A Protein Überblick

Protein Überblick

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This family member plays a role in cell-cell adhesion and angiogenesis. It functions in filopodia formation, cell migration and tube formation. Due to its presence at higher levels in tumor endothelium than in normal tissue endothelium, it is considered to be a candidate for tumor vascular targeting.

Genbezeichner und Symbole assoziert mit CLEC14A

  • C-type lectin domain containing 14A (CLEC14A)
  • C-type lectin domain family 14, member a (Clec14a)
  • 1200003C23Rik Protein
  • AI642649 Protein
  • C14orf27 Protein
  • CEG1 Protein
  • EGFR-5 Protein

Bezeichner auf Proteinebene für CLEC14A

C-type lectin domain family 14 member A , ClECT and EGF-like domain containing protein , epidermal growth factor receptor 5

GENE ID SPEZIES
161198 Homo sapiens
66864 Mus musculus
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