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CD68 encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. Zusätzlich bieten wir Ihnen CD68 Kits (33) und CD68 Proteine (25) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 629 products:
Human Monoclonal CD68 Primary Antibody für ICC, FACS - ABIN152106
Horny, Schaumburg-Lever, Bolz, Geerts, Kaiserling: Use of monoclonal antibody KP1 for identifying normal and neoplastic human mast cells. in Journal of clinical pathology 1990
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Mouse (Murine) Monoclonal CD68 Primary Antibody für FACS, ICC - ABIN4295377
Robertson, OConnell, Hudson, Seamark: Granulocyte-macrophage colony-stimulating factor (GM-CSF) targets myeloid leukocytes in the uterus during the post-mating inflammatory response in mice. in Journal of reproductive immunology 2000
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Human Monoclonal CD68 Primary Antibody für ICC, IHC (fro) - ABIN256057
da Costa, Annels, Faaij, Forsyth, Hogendoorn, Egeler: Presence of osteoclast-like multinucleated giant cells in the bone and nonostotic lesions of Langerhans cell histiocytosis. in The Journal of experimental medicine 2005
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Human Monoclonal CD68 Primary Antibody für FACS - ABIN1741593
Feuillard, Jacob, Valensi, Maynadié, Gressin, Chaperot, Arnoulet, Brignole-Baudouin, Drénou, Duchayne, Falkenrodt, Garand, Homolle, Husson, Kuhlein, Le Calvez, Sainty, Sotto, Trimoreau, Béné: Clinical and biologic features of CD4(+)CD56(+) malignancies. in Blood 2002
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Human Polyclonal CD68 Primary Antibody für IF (cc), IF (p) - ABIN671406
Zeng, Zhang, Li, Yang, Chen, Liu: A new method to isolate and culture rat kupffer cells. in PLoS ONE 2013
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Mouse (Murine) Polyclonal CD68 Primary Antibody für IHC (fro), IHC (p) - ABIN3044428
Guo, Liao, Huang, Wang, Huang, Liu: Reversal of adipose tissue loss by probucol in mice with deficiency of both scavenger receptor class B type 1 and LDL receptor on high fat diet. in Biochemical and biophysical research communications 2017
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Mouse (Murine) Polyclonal CD68 Primary Antibody für IHC (p), WB - ABIN5518672
Gu, Wu, Yao, Zeng, Shi, Lv, Luo, Song: Intratracheal administration of mitochondrial DNA directly provokes lung inflammation through the TLR9-p38 MAPK pathway. in Free radical biology & medicine 2015
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Human Polyclonal CD68 Primary Antibody für IHC (p), WB - ABIN3044053
Peng, Liu, Wei, Lv, Wang, Xiong, Wang, Altaf, Wang, He, Wang, Qu: P2X7R is involved in the progression of atherosclerosis by promoting NLRP3 inflammasome activation. in International journal of molecular medicine 2015
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Mouse (Murine) Polyclonal CD68 Primary Antibody für ELISA, IF - ABIN1586039
Wu, Chuang, Yang, Lin: A standardized aqueous extract of Anoectochilus formosanus ameliorated thioacetamide-induced liver fibrosis in mice: the role of Kupffer cells. in Bioscience, biotechnology, and biochemistry 2010
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Human Monoclonal CD68 Primary Antibody für CyTOF, FACS - ABIN4899672
Lumeng, Deyoung, Bodzin, Saltiel: Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity. in Diabetes 2006
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Findings indicate that human CD68 and its mouse ortholog macrosialin located in the lysosomal membrane and share many structural similarities.
Myeloid osteoclast precursors do not express CD68.
CD68, a putative receptor for sporozoite invasion of Kupffer cells that acts as a gateway for malaria infection of the liver.
Results showed that activated microglia in Alzheimer's disease-like mice showed two-step transition: a CD68-negative activated form at 6-9 months and a CD68-positive form from 12 months of age
Statins promote the beneficial remodeling of plaques in diseased mouse arteries through the stimulation of the CCR7 (zeige CCR7 Antikörper) / CD68 emigration pathway in macrophages
These findings demonstrate a role for CD68 in the function of osteoclasts.
CD68-null mononuclear phagocytes exhibited a trend toward enhanced antigen presentation to CD4+ T cells, indicating that CD68 may function to negatively regulate antigen uptake, loading, or major histocompatibility complex class II trafficking.
Atherogenic diet-induced reduction in lipid levels of Reversa model mouse leads to decreased monocyte-derived CD68-positive cells in advanced atherosclerotic plaques and is associated with emigration of these cells from the atherosclerotic plaques.
Macrosialin does not function as an oxLDL receptor on the cell surface.
Data show that macrosialin (CD68), a macrophage-specific protein, is increased by aging in selected brain regions of male C57BL/6NNia mice.
Taken together, these results suggested that the changes, including ox-LDL/LDL ratio, CD68(+)/RANK(+) cells number, and the levels of RANKL (zeige TNFSF11 Antikörper) and HMGB1 (zeige HMGB1 Antikörper) in AS patients, favored osteoclastogenesis.
High expression of CD68 is associated with nonalcoholic steatohepatitis.
increased amount of CD68+TAM (zeige CCNA1 Antikörper) in gaps of ductal tumor structures is protective against metastatic spread in regional lymph nodes.
Most cases of histiocytic sarcoma expressed histiocytic markers CD68 (6 of 7 cases), CD163 (zeige CD163 Antikörper) (5 of 5 cases), and PU.1 (3 of 4 cases).
Renal expression of CD68 and the chronicity index are associated with progression to chronic kidney disease in patients with proliferative lupus nephritis.
Results indicate that the expression of FoxP3 (zeige FOXP3 Antikörper) was not significantly associated with survival, and suggest prognostic significance of high CD68 expression in primary central nervous system lymphoma (PCNSL).
Her-2 (zeige ERBB2 Antikörper) overexpression results in ICA were similar to previous reports, the finding of 28% in HGD (zeige HGD Antikörper) was unexpected and may have clinical implications. Positive Her-2 (zeige ERBB2 Antikörper) DISH in 6% of LGD is novel, suggesting a role of Her-2 (zeige ERBB2 Antikörper) during BE progression
CD68 may play key roles in the pathogenesis of Alzheimer's disease (AD) and its complications may be via induction of inflammation; CD68 may be considered as a risk factor for development of AD and also psychotic symptoms in the patients
hCD68GFP/ApoE (zeige APOE Antikörper)(-/-) mice provide a new approach to study macrophage accumulation in atherosclerotic plaque progression and to identify cells recruited from adoptively transferred monocytes.
This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.
, CD68 antigen
, macrophage antigen CD68
, scavenger receptor class D, member 1