anti-CD244 Molecule, Natural Killer Cell Receptor 2B4 (CD244) Antikörper

CD244 encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. Zusätzlich bieten wir Ihnen CD244 Proteine (27) und CD244 Kits (10) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CD244 51744 Q9BZW8
CD244 64025 Q9JLM2
CD244 18106 Q07763
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Showing 10 out of 128 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC (p) A549 cells probed with Rabbit Anti-CD244 Polyclonal Antibody (ABIN740730) at 1:50 for 60 minutes followed by incubation with Goat Anti-Rabbit IgG FITC conjugated secondary at 1:100 (green) for 40 minutes compared to control cells (blue). Paraformaldehyde-fixed, paraffin embedded human kidney, Antigen retrieval by boiling in sodium citrate buffer (pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes, Blocking buffer (normal goat serum) at 37°C for 20min, Antibody incubation with Rabbit Anti-CD244 Polyclonal Antibody, Unconjugated  at 1:200 overnight at 4°C, followed by a conjugated secondary for 90 minutes and DAB staining. 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
304,36 €
Details
Human Maus Unkonjugiert FACS, IP Staining of human peripheral blood lymphocytes with MOUSE ANTI HUMAN CD244: LOW ENDOTOXIN(ABIN120311). 0.5 mg Anmelden zum Anzeigen 7 bis 9 Tage
594,00 €
Details
Human Maus PE FACS   100 Tests Anmelden zum Anzeigen 7 bis 9 Tage
528,00 €
Details
Human Ziege PE FACS Detection of 2B4/CD244/SLAMF4 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human NCAM-1/CD56 APC-conjugated Monoclonal Antibody. 100 Tests Anmelden zum Anzeigen 3 bis 4 Tage
255,00 €
Details
Human Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti- CD244 antibody, IHC(P) IHC(P): Human Tonsil Tissue Anti- CD244 antibody, Western blotting All lanes: Anti CD244  at 0.5ug/ml Lane 1: MCF-7 Whole Cell Lysate at 40ug Lane 2: HELA Whole Cell Lysate at 40ug Predicted bind size: 42KD Observed bind size: 42KD 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
298,57 €
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Human Ziege Unkonjugiert EIA, IP, WB   0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
357,50 €
Details
Human Kaninchen Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
357,50 €
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB HeLa cell lysates probed with Anti-CD244(Tyr271) Polyclonal Antibody, Unconjugated  at 1:5000 for 90 min at 37˚C. MCF-7 cell lysates probed with Anti-CD244(Tyr271) Polyclonal Antibody, Unconjugated  at 1:5000 for 90 min at 37˚C. 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
326,42 €
Details
Maus Ziege Biotin FACS, IHC, WB   50 μg Anmelden zum Anzeigen 3 bis 4 Tage
380,00 €
Details

CD244 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-CD244 Antikörper

  1. Mouse (Murine) Polyclonal CD244 Primary Antibody für FACS, IHC - ABIN4898999 : Cao, Wagers, Karsunky, Zhao, Reeves, Wong, Stevenson, Weissman, Contag: Heme oxygenase-1 deficiency leads to disrupted response to acute stress in stem cells and progenitors. in Blood 2008 (PubMed)

  2. Human Polyclonal CD244 Primary Antibody für IHC (p) - ABIN740730 : Peiffer, Wang, Zimmerman, Ransom, Carmella, Kuo, Chen, Oshima, Huang, Hecht, Stoner: Dietary Consumption of Black Raspberries or Their Anthocyanin Constituents Alters Innate Immune Cell Trafficking in Esophageal Cancer. in Cancer immunology research 2016 (PubMed)

  3. Human Polyclonal CD244 Primary Antibody für FACS - ABIN4895306 : Mattiola, Pesant, Tentorio, Molgora, Marcenaro, Lugli, Locati, Mavilio: Priming of Human Resting NK Cells by Autologous M1 Macrophages via the Engagement of IL-1β, IFN-β, and IL-15 Pathways. in Journal of immunology (Baltimore, Md. : 1950) 2015 (PubMed)

  4. Human Monoclonal CD244 Primary Antibody für FACS, IP - ABIN120311 : Romero, Zapater, Calvo, Kalko, de la Fuente, Tovar, Ockeloen, Pizcueta, Engel: CD229 (Ly9) lymphocyte cell surface receptor interacts homophilically through its N-terminal domain and relocalizes to the immunological synapse. in Journal of immunology (Baltimore, Md. : 1950) 2005 (PubMed)

Weitere Antikörper gegen CD244 Interaktionspartner

Human CD244 Molecule, Natural Killer Cell Receptor 2B4 (CD244) Interaktionspartner

  1. 2B4 expression is increased on CD4 (zeige CD4 Antikörper)+ T cells in septic patients

  2. Self-iNKR(-) NK cells in X-linked lymphoproliferative disease 1 patients are functional even in resting conditions, suggesting a role of the inhibitory 2B4/CD48 (zeige CD48 Antikörper) pathway in the education process during NK-cell maturation.

  3. our results provide strong evidence that CD244 co-operates with c-Kit (zeige KIT Antikörper) to regulate leukemogenesis through SHP-2 (zeige PTPN11 Antikörper)/p27 (zeige PAK2 Antikörper) signaling.

  4. SLAMF4 gene and surface protein expression was down-regulated in CD8 (zeige CD8A Antikörper)+ T cells from SLE patients compared with that in cells obtained from healthy donors. SLAMF4+ effector memory cells produced more granzyme B (zeige Gzmb Antikörper) and perforin (zeige PRF1 Antikörper) than SLAMF4- cells.

  5. GSK-3 (zeige GSK3b Antikörper) undergoes inhibitory phosphorylation at regulatory serine residues by the engagement of NKG2D (zeige KLRK1 Antikörper) and 2B4, either individually or in combination.

  6. Cytomegalovirus-Induced Expression of CD244 after Liver Transplantation Is Associated with CD8 (zeige CD8A Antikörper)+ T Cell Hyporesponsiveness to Alloantigen

  7. CD8 (zeige CD8A Antikörper)(+) T cells require 2B4 for Epstein-Barr virus-specific immune control, because 2B4 blockade after CD8 (zeige CD8A Antikörper)(+) T-cell depletion did not further aggravate symptoms of the infection.

  8. CD244 expression/signaling in tuberculosis correlates with high levels of a long noncoding RNA (lncRNA)-BC050410 [named as lncRNA-AS-GSTT1(1 (zeige GSTT1 Antikörper)-72) or lncRNA-CD244] in the CD244(+)CD8 (zeige CD8A Antikörper)(+) T-cell subpopulation.

  9. show that in addition to NKG2D (zeige KLRK1 Antikörper), human CEACAM1 (zeige CEACAM1 Antikörper) can inhibit NK-cell activation via NKp30 (zeige NCR3 Antikörper) or 2B4

  10. this study investigates the structural requirements for the recruitment of the human-activating NK-cell receptors NKG2D (zeige KLRK1 Antikörper) and 2B4 to detergent-resistant membrane fractions in the murine BA/F3 cell line and in the human NK-cell line NKL (zeige GLIS2 Antikörper).

Mouse (Murine) CD244 Molecule, Natural Killer Cell Receptor 2B4 (CD244) Interaktionspartner

  1. 2B4 expression is increased on CD4 (zeige CD4 Antikörper)+ T cells in septic animals

  2. 2B4 dampens T-independent B cell responses.

  3. DCs from CD244(-/-) mice elicited increased NK cell activation in vitro. These data add CD244 to a growing list of immuno-modulatory receptors found on DCs.

  4. Data show that enforced expression of inhibitor of differentiation protein Id3 (zeige ID3 Antikörper) specifically increased the persistence of Cd244 protein 2B4(+) virus-specific CD8 (zeige CD8A Antikörper)(+) T cells.

  5. Molecular dynamic simulation explains unbinding and unfolding of CD48 (zeige CD48 Antikörper)-2B4 protein complexes.

  6. Signaling via SLAMF4 controls expansion of cytotoxic CD8alphabeta(+) IELs, which regulate the reversible depletion of lamina propria phagocytes and inflammation in the small intestine.

  7. CD244 (2B4) has a regulatory effect on mast cells and eosinophils in murine allergic inflammation.

  8. NKG2D (zeige KLRK1 Antikörper) ligation relieves 2B4-mediated NK-cell self-tolerance in mice.

  9. blockade of CD28 (zeige CD28 Antikörper) signals in the presence of preserved CTLA-4 (zeige CTLA4 Antikörper) signals results in the unique up-regulation of 2B4 on primary CD8 (zeige CD8A Antikörper)(+) effectors, and that this 2B4 expression plays a critical functional role in controlling antigen-specific T8 cell responses

  10. In the absence of SAP (zeige APCS Antikörper), signaling through the SLAM (zeige SLAMF1 Antikörper) family members Ly108 (zeige SLAMF6 Antikörper) and 2B4 resulted in increased recruitment of the SHP-1 (zeige PTPN6 Antikörper) phosphatase, associated with altered SHP-1 (zeige PTPN6 Antikörper) localization and decreased activation of Src (zeige SRC Antikörper) kinases at the synapse.

CD244 Antigen-Profil

Protein Überblick

This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit CD244

  • CD244 molecule, natural killer cell receptor 2B4 (CD244) Antikörper
  • Cd244 molecule, natural killer cell receptor 2B4 (Cd244) Antikörper
  • CD244 natural killer cell receptor 2B4 (Cd244) Antikörper
  • 2B4 Antikörper
  • C9.1 Antikörper
  • CD244 Antikörper
  • F730046O15Rik Antikörper
  • Ly90 Antikörper
  • NAIL Antikörper
  • NKR2B4 Antikörper
  • Nmrk Antikörper
  • SLAMF4 Antikörper

Bezeichner auf Proteinebene für CD244

CD244 molecule, natural killer cell receptor 2B4 , natural killer cell receptor 2B4 , NK cell activation inducing ligand NAIL , NK cell activation-inducing ligand , NK cell type I receptor protein 2B4 , SLAM family member 4 , h2B4 , signaling lymphocytic activation molecule 4 , CD244 natural killer cell receptor 2B4 , NKR2B4 , non MHC restricted killing associated , non-MHC restricted killing associated , transmembrane NK cell receptor 2B4 , NK cell receptor 2B4

GENE ID SPEZIES
488644 Canis lupus familiaris
513468 Bos taurus
100594419 Nomascus leucogenys
51744 Homo sapiens
64025 Rattus norvegicus
18106 Mus musculus
Ausgewählte Anbieter für anti-CD244 (CD244) Antikörper
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