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anti-C1GALT1-Specific Chaperone 1 (C1GALT1C1) Antikörper

C1GALT1C1 encodes a type II transmembrane protein that is similar to the core 1 beta1,3-galactosyltransferase 1, which catalyzes the synthesis of the core-1 structure, also known as Thomsen-Friedenreich antigen, on O-linked glycans. Zusätzlich bieten wir Ihnen C1GALT1-Specific Chaperone 1 Proteine (7) und C1GALT1-Specific Chaperone 1 Kits (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
C1GALT1C1 29071 Q96EU7
C1GALT1C1 59048 Q9JMG2
C1GALT1C1 302499 Q499P3
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Top anti-C1GALT1-Specific Chaperone 1 Antikörper auf antikoerper-online.de

Showing 10 out of 13 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB Host: Rabbit  Target Name: C1galt1c1  Sample Tissue: Rat pancreas lysa... 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Maus Unkonjugiert WB Western Blot analysis of C1GALT1C1 expression in transfected 293T cell... C1GALT1C1 MaxPab polyclonal antibody. Western Blot analysis of C1GALT1... 50 μg Anmelden zum Anzeigen 8 bis 9 Tage
369,60 €
Details
Human Kaninchen Unkonjugiert ELISA, WB   50 μL Anmelden zum Anzeigen 7 bis 10 Tage
298,57 €
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Human Kaninchen Unkonjugiert WB   100 μL Anmelden zum Anzeigen 12 Days
299,73 €
Details
Human Maus Unkonjugiert WB   50 μg Anmelden zum Anzeigen 15 bis 21 Tage
552,99 €
Details
Human Maus Unkonjugiert WB   50 μg Anmelden zum Anzeigen 11 bis 14 Tage
880,00 €
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Human Kaninchen Unkonjugiert ELISA, WB   50 μL Anmelden zum Anzeigen 6 bis 8 Tage
495,58 €
Details
Human Kaninchen Unkonjugiert ELISA   200 μL Anmelden zum Anzeigen 6 bis 8 Tage
560,48 €
Details
Human Kaninchen Unkonjugiert ELISA, WB   200 μL Anmelden zum Anzeigen 6 bis 8 Tage
560,48 €
Details
Human Kaninchen Unkonjugiert   50 μL Anmelden zum Anzeigen 7 bis 17 Tage
382,15 €
Details

C1GALT1C1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Human ,
,
Mouse (Murine) ,

Rat (Rattus) ,

Weitere Antikörper gegen C1GALT1-Specific Chaperone 1 Interaktionspartner

Human C1GALT1-Specific Chaperone 1 (C1GALT1C1) Interaktionspartner

  1. Data suggest that patients with IgA nephropathy exhibit higher microRNA-374b in B cells compared to controls; microRNA-374b appears to target PTEN (phosphatase and tensin homolog (zeige PTEN Antikörper)) and Cosmc (C1GALT1 specific chaperone 1) proteins.

  2. These results indicate that Tn antigens expression and T-synthase (zeige C1GALT1 Antikörper) inactivity in HT-29-Tn+ cells can be related to the absence of the Cosmc gene coding sequence in Cosmc active alleles

  3. the impact of COSMC mediated Tn antigen expression in two human pancreatic ductal adenocarcinoma cell lines on cellular oncogenic properties, were investigated.

  4. hypermethylation of Cosmc promoter region could be a key mechanism for the reduction of Cosmc mRNA expression in IgAN lymphocytes with associated increase in aberrantly glycosylated IgA1

  5. Cosmc and T-synthase (zeige C1GALT1 Antikörper) are transcriptionally regulated at a basal level by the specificity protein/Kruppel-like transcription factor (zeige KLF4 Antikörper) family of members.

  6. CBRT is a unique recognition motif for Cosmc to promote its regulation and formation of active T-synthase (zeige C1GALT1 Antikörper) and represents the first sequence-specific chaperone recognition system in the ER/Golgi required for normal protein O-glycosylation

  7. Data indicate that cytotoxin associated gene A protein (CagA (zeige S100A8 Antikörper)) promoted the underglycosylation of IgA1, which at least partly attributed to the downregulation of beta1,3-galactosyltransferase (C1GALT1 (zeige C1GALT1 Antikörper)) and its chaperone Cosmc.

  8. overexpression of Cosmc is associated with colorectal cancer.

  9. COSMC is a novel regulator for VEGFR2 (zeige KDR Antikörper) signaling in endothelial cells and dysregulation of COSMC expression may contribute to the pathogenesis of hemangioma

  10. The mRNA expression level of Cosmc gene in IgA nephropathy patients was significantly lower than that of controls. De-methylation modification up regulated the Cosmc gene expression significantly.

Mouse (Murine) C1GALT1-Specific Chaperone 1 (C1GALT1C1) Interaktionspartner

  1. Cosmc is an essential chaperone for correct protein O-glycosylation.

  2. a somatic mutation in the chaperone gene Cosmc abolished function of a glycosyltransferase (zeige GTDC2 Antikörper), disrupting O-glycan Core 1 synthesis & creating a tumor-specific glycopeptidic neo-epitope consisting of a monosaccharide and a specific wild-type protein sequence

C1GALT1-Specific Chaperone 1 (C1GALT1C1) Antigen-Profil

Protein Überblick

This gene encodes a type II transmembrane protein that is similar to the core 1 beta1,3-galactosyltransferase 1, which catalyzes the synthesis of the core-1 structure, also known as Thomsen-Friedenreich antigen, on O-linked glycans. This gene product lacks the galactosyltransferase activity itself, but instead acts as a molecular chaperone required for the folding, stability and full activity of the core 1 beta1,3-galactosyltransferase 1. Mutations in this gene have been associated with Tn syndrome. Alternatively spliced transcript variants encoding the same protein have been identified.

Genbezeichner und Symbole assoziert mit C1GALT1C1

  • C1GALT1-specific chaperone 1 (c1galt1c1) Antikörper
  • C1GALT1-specific chaperone 1 (C1GALT1C1) Antikörper
  • C1GALT1-specific chaperone 1 (C1galt1c1) Antikörper
  • 1500002I11Rik Antikörper
  • AB030184 Antikörper
  • C1GalT2 Antikörper
  • C38H2-L1 Antikörper
  • C81205 Antikörper
  • Cosmc Antikörper
  • MGC88924 Antikörper
  • MST143 Antikörper
  • RGD1311230 Antikörper
  • TNPS Antikörper
  • wu:fc17f08 Antikörper
  • wu:fc59b02 Antikörper
  • zgc:66375 Antikörper

Bezeichner auf Proteinebene für C1GALT1C1

fc59b02 , core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 2 , C1GALT1-specific chaperone 1 , Core 1 beta3-galactosyltransferase-specific molecular chaperone , C1GALT1-specific chaperone 1-like , c1GALT1-specific chaperone 1-like , C1Gal-T2 , C38H2-like protein 1 , beta 1,3-galactosyltransferase 2 , core 1 beta1,3-galactosyltransferase 2 , core 1 beta3-Gal-T2 , core 1 beta3-galactosyltransferase-specific molecular chaperone , beta1,3-galactosyltransferase 2 , mC1Gal-T2

GENE ID SPEZIES
324052 Danio rerio
422362 Gallus gallus
448225 Xenopus (Silurana) tropicalis
465837 Pan troglodytes
495031 Xenopus laevis
696662 Macaca mulatta
100397132 Callithrix jacchus
100441547 Pongo abelii
100594094 Nomascus leucogenys
29071 Homo sapiens
59048 Mus musculus
302499 Rattus norvegicus
531644 Bos taurus
Ausgewählte Anbieter für anti-C1GALT1-Specific Chaperone 1 (C1GALT1C1) Antikörper
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