anti-Bromodomain PHD Finger Transcription Factor (BPTF) Antikörper

BPTF was identified by the reactivity of its encoded protein to a monoclonal antibody prepared against brain homogenates from patients with Alzheimer's disease. Zusätzlich bieten wir Ihnen und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
BPTF 207165  
BPTF 303617  
BPTF 2186 Q12830
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Top anti-BPTF Antikörper auf antikoerper-online.de

Showing 10 out of 40 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Maus Unkonjugiert ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Western blot analysis using BPTF mAb against HEK293 (1) and BPTF (AA: 503-670) -hIgGFc transfected HEK293 (2) cell lysate. 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$430.10
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), IP, WB Immunohistochemistry-Paraffin: BPTF/FALZ Antibody [ABIN1885878] - FFPE section of human breast carcinoma. Affinity purified rabbit anti-FALZ/BPTF used at a dilution of 1:250. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$486.94
Details
Human Maus Unkonjugiert IHC (p), ELISA, WB Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Anmelden zum Anzeigen 7 bis 9 Tage
$451.00
Details
Human Maus Unkonjugiert ELISA, WB   0.1 mL Anmelden zum Anzeigen 4 bis 6 Tage
$481.25
Details
Human Maus Unkonjugiert DB 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$285.71
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-BPTF/FALZ Polyclonal Antibody, Unconjugated (ABIN1386560) at 1:200 followed by conjugation to the secondary antibody and DAB staining Paraformaldehyde-fixed, paraffin embedded rat kidney, Antigen retrieval by boiling in sodium citrate buffer (pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes, Blocking buffer (normal goat serum) at 37°C for 20min, Antibody incubation with 	BPTF/FALZ Polyclonal Antibody, Unconjugated  at 1:500 overnight at 4°C, followed by a conjugated secondary and DAB staining. 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$295.90
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: BPTF/FALZ Antibody [NBP1-84756] Staining of human cell line A-431 shows positivity in nucleus but not nucleoli. Immunohistochemistry-Paraffin: BPTF/FALZ Antibody [NBP1-84756] - Staining of human adrenal gland shows strong cytoplasmic positivity in cortical cells. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$439.69
Details
Human Kaninchen Unkonjugiert ICC, IF Immunocytochemistry/Immunofluorescence: BPTF/FALZ Antibody  - Staining of human cell line U-251 MG shows localization to nucleoplasm. 100 μL Anmelden zum Anzeigen 10 bis 13 Tage
$439.69
Details
Human Kaninchen Unkonjugiert IP, WB   100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$1,145.83
Details
Human Maus Unkonjugiert EIA, WB 0.1 mL Anmelden zum Anzeigen 6 bis 8 Tage
$423.50
Details

BPTF Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-BPTF Antikörper

  1. Human Monoclonal BPTF Primary Antibody für ELISA, WB - ABIN968990 : Landry, Sharov, Piao, Sharova, Xiao, Southon, Matta, Tessarollo, Zhang, Ko, Kuehn, Yamaguchi, Wu: Essential role of chromatin remodeling protein Bptf in early mouse embryos and embryonic stem cells. in PLoS genetics 2008 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal BPTF Primary Antibody für ELISA, WB - ABIN965692 : Imamura, Oda, Katahira, Bundo, Pike, Ratcliffe, Kitamura: BLNK binds active H-Ras to promote B cell receptor-mediated capping and ERK activation. in The Journal of biological chemistry 2009 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal BPTF Primary Antibody für ICC, IF - ABIN188587 : Goldman, Garlick, Kingston: Chromatin remodeling by imitation switch (ISWI) class ATP-dependent remodelers is stimulated by histone variant H2A.Z. in The Journal of biological chemistry 2010 (PubMed)

Weitere Antikörper gegen BPTF Interaktionspartner

Mouse (Murine) Bromodomain PHD Finger Transcription Factor (BPTF) Interaktionspartner

  1. enhanced activity was observed for individual CD8 (zeige CD8A Antikörper)(+) T-cell clones from mice bearing BPTF-silenced tumors.

  2. These findings therefore reveal a vital role for BPTF in T and Treg cell function and immune homeostasis.

  3. We find that the melanocyte stem cells from these animals are abnormal and that once they are stimulated at anagen, Bptf is required to ensure the expression of melanocyte markers and their differentiation into mature adult melanocytes.

  4. NURF regulation occurs partly through physical and functional interactions with the ubiquitous and multivalent factors Ctcf and cohesin

  5. Results suggest that BPTF/FAC1 is essential in the extraembryonic lineage for correct development of the ectoplacental cone and fetomaternal interactions.

  6. study concludes that Bptf likely regulates genes and signaling pathways essential for the development of key tissues of the early mouse embryo

Human Bromodomain PHD Finger Transcription Factor (BPTF) Interaktionspartner

  1. Haploinsufficiency of BPTF gene is associated with Syndromic Developmental and Speech Delay, Postnatal Microcephaly, and Dysmorphic Features.

  2. Two new signals were observed at genome-wide significance (P < 5 x 10-8), namely, rs7216064 (17q24.3, BPTF), for overall lung adenocarcinoma risk, and rs3817963 (6p21.3, BTNL2 (zeige BTNL2 Antikörper)) which is specific to cases with EGFR (zeige EGFR Antikörper) mutations. In further sub-analyses by EGFR (zeige EGFR Antikörper) status, rs9387478 (ROS1 (zeige ROS1 Antikörper)/DCBLD1) and rs2179920 (HLA-DPB1 (zeige HLA-DPB1 Antikörper)) showed stronger estimated associations in EGFR (zeige EGFR Antikörper)-positive compared to EGFR (zeige EGFR Antikörper)-negative cases

  3. NRP2 (zeige NELL2 Antikörper) inhibits WDFY1 (zeige WDFY1 Antikörper) transcription by preventing the nuclear localization of a transcription factor, Fetal ALZ50-reactive clone 1 (FAC1).

  4. Overexpression of BPTF is associated with melanoma cell survival and progression.

  5. somatic frameshift mutations of BPTF were present in gastric cancer and colorectal cancers

  6. BPTF plays an essential role in cell growth and survival by targeting multiply signaling pathways in human lung cancers

  7. High BPTF expression was significantly correlated with tumor progression and may be a potent prognostic marker of colorectal cancer.

  8. The PHD (zeige PDC Antikörper)-adjacent bromodomain in BPTF binds with marked selectivity H4K16ac, in combination with H3K4me3 at the mononucleosome level.

  9. the novel translocation breakpoint within the BPTF gene is associated with a pre-malignant phenotype

  10. hkelch-like ECH (zeige NFE2L2 Antikörper)-associated protein 1 regulates FAC1 in addition to its known role in control of Nrf2 (zeige GABPA Antikörper)

BPTF Antigen-Profil

Protein Überblick

This gene was identified by the reactivity of its encoded protein to a monoclonal antibody prepared against brain homogenates from patients with Alzheimer's disease. Analysis of the original protein (fetal Alz-50 reactive clone 1, or FAC1), identified as an 810 aa protein containing a DNA-binding domain and a zinc finger motif, suggested it might play a role in the regulation of transcription. High levels of FAC1 were detected in fetal brain and in patients with neurodegenerative diseases. The protein encoded by this gene is actually much larger than originally thought, and it also contains a C-terminal bromodomain characteristic of proteins that regulate transcription during proliferation. The encoded protein is highly similar to the largest subunit of the Drosophila NURF (nucleosome remodeling factor) complex. In Drosophila, the NURF complex, which catalyzes nucleosome sliding on DNA and interacts with sequence-specific transcription factors, is necessary for the chromatin remodeling required for transcription. Two alternative transcripts encoding different isoforms have been described completely.

Genbezeichner und Symbole assoziert mit BPTF

  • bromodomain PHD finger transcription factor (Bptf) Antikörper
  • bromodomain PHD finger transcription factor (BPTF) Antikörper
  • bromodomain PHD finger transcription factor (LOC100358904) Antikörper
  • bromodomain PHD finger transcription factor (bptf) Antikörper
  • fetal alzheimer antigen, falz (AaeL_AAEL015015) Antikörper
  • fetal alzheimer antigen, falz (AaeL_AAEL012607) Antikörper
  • fetal alzheimer antigen, falz (CpipJ_CPIJ011285) Antikörper
  • 9430093H17Rik Antikörper
  • BPTF Antikörper
  • FAC1 Antikörper
  • FALZ Antikörper
  • NURF301 Antikörper

Bezeichner auf Proteinebene für BPTF

fetal Alzheimer antigen , nucleosome-remodeling factor subunit BPTF , bromodomain PHD finger transcription factor , nucleosome-remodeling factor subunit BPTF-like , fetal alzheimer antigen, falz , bromodomain and PHD domain transcription factor , bromodomain and PHD finger-containing transcription factor , fetal Alz-50 clone 1 protein , fetal Alz-50 reactive clone 1 , nucleosome remodeling factor, large subunit

GENE ID SPEZIES
207165 Mus musculus
303617 Rattus norvegicus
454840 Pan troglodytes
480467 Canis lupus familiaris
532986 Bos taurus
100063881 Equus caballus
100079560 Ornithorhynchus anatinus
100358904 Oryctolagus cuniculus
100494204 Xenopus (Silurana) tropicalis
100525424 Sus scrofa
100594415 Nomascus leucogenys
5565968 Aedes aegypti
5576547 Aedes aegypti
6043987 Culex quinquefasciatus
2186 Homo sapiens
Ausgewählte Anbieter für anti-BPTF (BPTF) Antikörper
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