anti-Beaded Filament Structural Protein 2, Phakinin (BFSP2) Antikörper

More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Zusätzlich bieten wir Ihnen BFSP2 Proteine (4) und BFSP2 Kits (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
BFSP2 300966  
BFSP2 8419 Q13515
BFSP2 107993 Q6NVD9
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Top anti-BFSP2 Antikörper auf antikoerper-online.de

Showing 10 out of 45 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-BFSP2 Antibody Titration: 1.0 ug/ml Positive Control: 293T Whole Cell 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Maus Unkonjugiert IHC, WB Immunohistochemistry: phakinin Antibody (4E7) [NBP2-46573] - Analysis of Adenocarcinoma of Human ovary tissue. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min) Immunohistochemistry: phakinin Antibody (4E7) [NBP2-46573] - Analysis of Carcinoma of Human liver tissue.(Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min) 0.1 mL Anmelden zum Anzeigen 3 bis 6 Tage
341,00 €
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Antigen: 2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Rabbit Anti-Goat IgG at 1: 5000;  TMB staining Read the data in Microplate Reader by 450nm. 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
304,36 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB   50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
Details
Rind (Kuh) Meerschweinchen Unkonjugiert IHC (fro), WB   0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
385,00 €
Details
Human Maus Unkonjugiert WB   100 μL Anmelden zum Anzeigen 11 bis 14 Tage
583,17 €
Details
Human Maus Unkonjugiert IHC (p), WB   100 μL Anmelden zum Anzeigen 11 bis 14 Tage
583,17 €
Details
Human Kaninchen Alexa Fluor 594 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen Alexa Fluor 647 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
Details
Human Kaninchen Alexa Fluor 350 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
Details

BFSP2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Weitere Antikörper gegen BFSP2 Interaktionspartner

Human Beaded Filament Structural Protein 2, Phakinin (BFSP2) Interaktionspartner

  1. We report a novel mutation (p.G112E) in the BFSP2 gene, underscoring the physiological importance of the beaded filament protein and supporting its role in human cataract formation.

  2. Data show that BFSP2 and PITX3 (zeige PITX3 Antikörper), hitherto known to cause eye defects only in a dominant fashion, can also present recessively.

  3. The Y-sutural opacity in the lens might be the typical and earliest sign for cataract caused by the BFSP2 mutation. In addition, a myopia susceptibility locus in this region, which might also be associated with the mutation in BFSP2.

  4. Progressive isolated sutural cataract associated with deletion mutation of BFSP2 gene in Chinese pedigree. Physiological importance of beaded filament protein. Role of BFSP2 in human cataract formation.

  5. Progressive phenotype has provided more evidence for the heterogeneity of congenital cataract caused by BFSP2 mutations and for the important role BFSP2 plays in cataract formation.

  6. This is the first reported case of a congenital lamellar cataract phenotype associated with the mutation of Arg339His (P.R339H) in BFSP2.

Mouse (Murine) Beaded Filament Structural Protein 2, Phakinin (BFSP2) Interaktionspartner

  1. CP49 is involved in a functional synergy critical for regulating lens fiber cell geometry, transparency, and mechanical stiffness.

  2. disruption of the Hsf4 (zeige HSF4 Antikörper) gene leads to cataracts via at least three pathways: down-regulation of gamma-crystallin, particularly gamma S-crystallin (zeige CRYGS Antikörper); decreased lens beaded filament expression; and loss of post-translational modification of alpha A-crystallin (zeige CRYAA Antikörper)

BFSP2 Antigen-Profil

Protein Überblick

More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, the protein product of this gene (phakinin), and filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene have been associated with juvenile-onset, progressive cataracts and Dowling-Meara epidermolysis bullosa simplex.

Genbezeichner und Symbole assoziert mit BFSP2

  • beaded filament structural protein 2, phakinin (Bfsp2) Antikörper
  • beaded filament structural protein 2, phakinin (BFSP2) Antikörper
  • beaded filament structural protein 2, phakinin (LOC100222605) Antikörper
  • AI448593 Antikörper
  • Bfsp2 Antikörper
  • CP47 Antikörper
  • CP49 Antikörper
  • CP49INS Antikörper
  • CTRCT12 Antikörper
  • LIFL-L Antikörper
  • LOC100222605 Antikörper
  • PHAKOSIN Antikörper

Bezeichner auf Proteinebene für BFSP2

beaded filament structural protein 2, phakinin , cytoskeletal protein CP 49 , phakinin , phakinin-like , 49 kDa cytoskeletal protein , beaded filament protein CP49 , bfps2, Cytoskeletal protein, 49-kD , lens fiber cell beaded filament protein CP 47 , lens fiber cell beaded filament protein CP 49 , lens intermediate filament-like light , CP 47 , CP47 , CP49

GENE ID SPEZIES
300966 Rattus norvegicus
396141 Gallus gallus
460708 Pan troglodytes
100101576 Oryctolagus cuniculus
100222605 Taeniopygia guttata
100306969 Cavia porcellus
100404357 Callithrix jacchus
100441274 Pongo abelii
100594242 Nomascus leucogenys
8419 Homo sapiens
281645 Bos taurus
107993 Mus musculus
608938 Canis lupus familiaris
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