anti-Anaphase Promoting Complex Subunit 11 (ANAPC11) Antikörper

Probably catalytic subunit of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin- protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. Zusätzlich bieten wir Ihnen Anaphase Promoting Complex Subunit 11 Proteine (9) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ANAPC11 498030  
ANAPC11 51529 Q9NYG5
ANAPC11 66156 Q9CPX9
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Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, IP, WB Conjugation pathways for ubiquitin and ubiquitin-like modifiers (UBLs). Most modifiers mature by proteolytic processing from inactive precursors (a, amino acid). Arrowheads point to the cleavage sites. Ubiquitin is expressed either as polyubiquitin or as a fusion with ribosomal proteins. Conjugation requires activating (E1) and conjugating (E2) enzymes that form thiolesters (S) with the modifiers. Modification of cullins by RUB involves SCF(SKP1/cullin-1/F-box protein) /CBC(cullin-2/elongin B/elonginC) -like E3 enzymes that are also involved in ubiquitination. In contrast to ubiquitin, the UBLs do not seem to form multi-UBL chains. UCRP(ISG15) resembles two ubiquitin moieties linked headto- tail. Whether HUB1 functions as a modifier is currently unclear. APG12 and URM1 are distinct from the other modifiers because they are unrelated in sequence to ubiquitin. Data contributed by S.Jentsch, see references below. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
495,00 €
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Human Kaninchen Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
357,50 €
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Human Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 3 bis 4 Tage
349,82 €
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Human Maus Unkonjugiert IF, IHC (p), WB 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
583,17 €
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Human Maus Unkonjugiert IF, WB 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
583,17 €
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Human Kaninchen Unkonjugiert ELISA, IHC, IHC (p), WB   0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
410,00 €
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Human Kaninchen Unkonjugiert ELISA, ICC, IF, WB Immunocytochemistry/Immunofluorescence: Apc11 Antibody [NBP1-76260] - Immunofluorescence of APC11 in 3T3 cells with APC11 antibody at 20 ug/mL. Western Blot: Apc11 Antibody [NBP1-76260] - Analysis of APC11 in 3T3 cell tissue lysate with APC11 antibody at (A) 1 and (B) 2 ug/mL. 0.1 mg Anmelden zum Anzeigen 3 bis 6 Tage
341,00 €
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Human Maus Unkonjugiert IF, IHC, WB Immunofluorescence: Apc11 Antibody (3F5) [NBP2-45493] - Analysis of COS7 cells transiently transfected by pCMV6-ENTRY ANAPC11. Immunohistochemistry: Apc11 Antibody (3F5) [NBP2-45493] - Analysis of Carcinoma of Human lung tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min) 0.1 mL Anmelden zum Anzeigen 3 bis 6 Tage
391,00 €
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Human Kaninchen Unkonjugiert IP, WB Conjugation pathways for ubiquitin and ubiquitin-like modifiers (UBLs). Most modifiers mature by proteolytic processing from inactive precursors (a 100 μL Anmelden zum Anzeigen 5 bis 7 Tage
412,76 €
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Human Maus Unkonjugiert ELISA, WB Detection limit for recombinant GST tagged ANAPC11 is approximately 0.03 ng/mL as a capture antibody. 0.1 mg Anmelden zum Anzeigen 12 bis 16 Tage
454,76 €
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ANAPC11 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Anaphase Promoting Complex Subunit 11 Antikörper

  1. Human Polyclonal ANAPC11 Primary Antibody für EIA, IP - ABIN117941 : Chan, Lee, Chim, Kok, Waye, Lee, Fung, Tsui: Molecular cloning and characterization of a RING-H2 finger protein, ANAPC11, the human homolog of yeast Apc11p. in Journal of cellular biochemistry 2001 (PubMed)
    Zeige alle 8 Referenzen für 117941

  2. Human Polyclonal ANAPC11 Primary Antibody für ELISA, IHC - ABIN4281020 : Ohta, Michel, Xiong: Association with cullin partners protects ROC proteins from proteasome-dependent degradation. in Oncogene 2000 (PubMed)
    Zeige alle 2 Referenzen für 4281020

Weitere Antikörper gegen Anaphase Promoting Complex Subunit 11 Interaktionspartner

Human Anaphase Promoting Complex Subunit 11 (ANAPC11) Interaktionspartner

  1. siRNA targeted against Apc11 could hamper entry into G2/M phase.

  2. The authors showed, in vitro, a direct interaction between Orf virus anaphase promoting complex regulator and APC2 and its interference with interactions between APC11 and APC2.

  3. Studies indicate that APC (zeige APC Antikörper)/C(Cdh1 (zeige CDH1 Antikörper)) is required to maintain genomic stability.

  4. APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex.

  5. Inhibition of APC11 function by H(2)O(2) contributes to the delay in cell cycle progression through mitosis that is characteristic of cells subjected to oxidative stress

Arabidopsis thaliana Anaphase Promoting Complex Subunit 11 (ANAPC11) Interaktionspartner

  1. Data indicate that the Anaphase Promoting Complex subunit 11 (APC11) gene carries a constitutive single-nucleotide exon.

Anaphase Promoting Complex Subunit 11 (ANAPC11) Antigen-Profil

Protein Überblick

Probably catalytic subunit of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin- protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin- conjugating E2 enzymes, it catalyzes the formation of protein- ubiquitin conjugates that are subsequently degraded by the 26S proteasome. In early mitosis, the APC/C is activated by CDC20 and targets securin PDS1, the B-type cyclin CLB5, and other anaphase inhibitory proteins for proteolysis, thereby triggering the separation of sister chromatids at the metaphase-to-anaphase transition. In late mitosis and in G1, degradation of CLB5 allows activation of the APC/C by CDH1, which is needed to destroy CDC20 and the B-type cyclin CLB2 to allow exit from mitosis and creating the low CDK state necessary for cytokinesis and for reforming prereplicative complexes in G1 prior to another round of replication. APC11 is required to recruit the ubiquitin- conjugating enzyme E2 to the APC/C.

Genbezeichner und Symbole assoziert mit ANAPC11

  • anaphase promoting complex subunit 11 (anapc11) Antikörper
  • anaphase promoting complex subunit 11 (Anapc11) Antikörper
  • anaphase-promoting complex subunit 11-like (LOC615066) Antikörper
  • Apc11p (APC11) Antikörper
  • anaphase-promoting complex subunit Apc11 (apc11) Antikörper
  • similar to S. cerevisiae APC11 (YDL008W) anaphase promoting complex subunit (APC11) Antikörper
  • ubiquitin-protein ligase Anaphase Promoting Complex (APC11) Antikörper
  • anaphase promoting complex subunit 11 (APC11) Antikörper
  • hypothetical protein (APC11) Antikörper
  • anaphase-promoting complex/cyclosome 11 (APC11) Antikörper
  • anaphase promoting complex subunit 11 (ANAPC11) Antikörper
  • anaphase promoting complex subunit 11 (LOC692923) Antikörper
  • APC11 anaphase promoting complex subunit 11 homolog (yeast) (anapc11) Antikörper
  • anaphase-promoting complex subunit 11 (APC11) Antikörper
  • 1110011I19Rik Antikörper
  • anapc11 Antikörper
  • anaphase-promoting complex/cyclosome 11 Antikörper
  • APC11 Antikörper
  • Apc11p Antikörper
  • DDBDRAFT_0187183 Antikörper
  • DDBDRAFT_0231277 Antikörper
  • DDB_0187183 Antikörper
  • DDB_0231277 Antikörper
  • F10A16.17 Antikörper
  • F10A16_17 Antikörper
  • R75218 Antikörper
  • RGD1561880 Antikörper
  • si:dkey-237i9.4 Antikörper
  • zgc:153671 Antikörper

Bezeichner auf Proteinebene für ANAPC11

anaphase promoting complex subunit 11 , anaphase promoting complex subunit 11 homolog , anaphase-promoting complex subunit 11 , anaphase promoting complex subunit 11-like , Apc11p , Catalytic core subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition , anaphase-promoting complex subunit Apc11 , potential anaphase-promoting complex subunit Apc11 , ubiquitin-protein ligase Anaphase Promoting Complex , hypothetical protein , anaphase-promoting complex/cyclosome 11 , APC11 anaphase promoting complex subunit 11 homolog , cyclosome subunit 11 , anaphase promoting complex subunit 11 (yeast APC11 homolog) , hepatocellular carcinoma-associated RING finger protein , APC11

GENE ID SPEZIES
496247 Xenopus laevis
496610 Xenopus (Silurana) tropicalis
498030 Rattus norvegicus
615066 Bos taurus
851554 Saccharomyces cerevisiae S288c
2543187 Schizosaccharomyces pombe 972h-
3639005 Candida albicans SC5314
4852029 Scheffersomyces stipitis CBS 6054
5718640 Chlamydomonas reinhardtii
7203954 Phaeodactylum tricornutum CCAP 1055/1
8248072 Micromonas sp. RCC299
8625855 Dictyostelium discoideum AX4
9320604 Arabidopsis lyrata subsp. lyrata
454972 Pan troglodytes
483370 Canis lupus familiaris
692923 Bombyx mori
768140 Danio rerio
100173127 Pongo abelii
51529 Homo sapiens
66156 Mus musculus
616275 Bos taurus
819756 Arabidopsis thaliana
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