anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4) Antikörper

The protein encoded by ABCC4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Zusätzlich bieten wir Ihnen ABCC4 Kits (11) und ABCC4 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ABCC4 10257 O15439
ABCC4 239273  
ABCC4 170924  
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Top anti-ABCC4 Antikörper auf antikoerper-online.de

Showing 10 out of 171 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Ziege Unkonjugiert IHC, ELISA, WB ABIN185302 staining (0.5µg/ml) of rat renal cortex membranes (20µg total protein per lane). Detected by western blot using chemiluminescence. Data kindly provided by Dr. Antje Steinbach, Ernst-Moritz-Arndt University of Greifswald. ABIN185302 (2.5µg/ml) staining of paraffin embedded Human Prostate. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$326.89
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-ABCC4 Antibody Titration: 1.0 ug/ml Positive Control: 721_B Whole Cell ABCC4 is supported by BioGPS gene expression data to be expressed in 721_B 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Ziege Unkonjugiert ICC, IF, IHC (p), IHC, ELISA, WB Immunohistochemistry: MRP4 Antibody [ABIN250309] - NB100-1478 (2.5ug/ml) staining of paraffin embedded Human Prostate. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. ABIN250309 staining (0.5µg/ml) of Rat renal cortex membranes (20µg total protein per lane). Detected by western blot using chemiluminescence. Data kindly provided by Dr. Antje Steinbach, Ernst-Moritz-Arndt University of Greifswald 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$408.19
Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti-MRP4 Picoband antibody,  IHC(P): Rat Intestine Tissue Anti-MRP4 Picoband antibody,  IHC(P): Mouse Intestine Tissue 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of anti-ABCC4 Antibody (C-term) (ABIN391639) in CEM cell line lysates (35 µg/lane). ABCC4 (arrow) was detected using the purified polyclonal antibody. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of anti-ABCC4 Antibody (C-term) in CEM cell line lysates (35ug/lane). ABCC4 (arrow) was detected using the purified Pab. 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Maus Unkonjugiert FACS, IHC, ELISA, WB 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$430.10
Details
Human Maus Unkonjugiert WB ABCC4 monoclonal antibody (M03), clone 1B2 Western Blot analysis of ABCC4 expression in Hela NE on formalin-fixed paraffin-embedded human prostate (antibody concentration 3 µg/mL). 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$450.00
Details
Human Kaninchen Unkonjugiert WB   100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Human Kaninchen Unkonjugiert WB Lane 3: Recombinant Human ABCC4 Protein 2.5ng 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$200.00
Details

ABCC4 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-ABCC4 Antikörper

  1. Human Polyclonal ABCC4 Primary Antibody für ICC, IF - ABIN250309 : Cheng, Ren, Jackson: Multidrug resistance protein 4 mediates cAMP efflux from rat preglomerular vascular smooth muscle cells. in Clinical and experimental pharmacology & physiology 2010 (PubMed)
    Show all 7 Pubmed References

  2. Human Polyclonal ABCC4 Primary Antibody für IHC, ELISA - ABIN185302 : Schuetz, Connelly, Sun, Paibir, Flynn, Srinivas, Kumar, Fridland: MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs. in Nature medicine 1999 (PubMed)
    Show all 6 Pubmed References

  3. Human Monoclonal ABCC4 Primary Antibody für FACS, IHC - ABIN1724860 : Bebes, Kis, Nagy, Kurunczi, Polyánka, Bata-Csörgo, Kemény, Dobozy, Széll: The expressions of ABCC4 and ABCG2 xenobiotic transporters in human keratinocytes are proliferation-related. in Archives of dermatological research 2012 (PubMed)

Weitere Antikörper gegen ABCC4 Interaktionspartner

Cow (Bovine) ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4) Interaktionspartner

  1. MRP4 is a functional prostaglandin carrier under the regulation of oxytocin in the bovine endometrium.

Human ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4) Interaktionspartner

  1. ABCC4 variant (rs4148500) was significantly associated with hyperuricemia and gout. The gout risk allele was associated with fractional excretion of uric acid in male individuals.

  2. ABCC4 functional SNP in the 3' splice acceptor site of exon 8 (G912T) is associated with unfavorable clinical outcome in children with acute lymphoblastic leukemia

  3. Data suggest that common SNPs in MRP4/ABCC4 (evaluated here via site-directed mutagenesis in recombinant proteins expressed in kidney cell lines) are responsible for variations in transport of methylated arsenic metabolites (major urinary arsenic metabolites in humans), prostaglandin E2, and estradiol-17 beta-glucuronide.

  4. Data indicate that R-flurbiprofen inhibits multidrug resistance-associated protein 4 (MRP4, ABCC4)-mediated prostaglandins (PG) transport.

  5. Analysis of gene-gene interactions with CYP2B6 (zeige CYP2B6 Antikörper) was particularly useful to reinforce the role of MRP4 and to reveal unknown associations, such as that of DRD3 (zeige DRD3 Antikörper).

  6. The tagSNP ABCC4 rs17268122 appears to be a prognostic factor in locally advanced rectal cancer treated with neoadjuvant chemoradiotherapy (nCRT) and surgery, independently of response to nCRT

  7. ABCC4 plays a protective role against cytarabine-mediated insults in leukemic and host myeloid cells.

  8. Results demonstrated the capacity of MRP4 to confer resistance to arsenite (AsIII), as evidenced by cell survival assays when treated with AsIII in the presence or absence of its two differential inhibitors.

  9. Osteoarthritis patient platelets presented a higher expression of MRP4.

  10. Sulfate metabolites R-6-S and R-4'-S were generated from raloxifene in SULT293 expression HEK293 cells. Cellular excretion of the raloxifene sulfates was mainly mediated by BCRP and MRP4.

Mouse (Murine) ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4) Interaktionspartner

  1. The diversity at N-termini in these protein isoforms explains the diverse function of ABCC4 in mouse.

  2. ABCC4 plays a protective role against cytarabine-mediated insults in leukemic and host myeloid cells.

  3. P-gp, Bcrp, Mrp1 and Mrp4 are differentially expressed at the outer and inner blood retinal barrier, resulting in an altered ability to limit substrate distribution at the retina as compared with the blood brain barrier

  4. These findings have important clinical implications because they directly highlight an important relationship between ABCC4 transporter function and phosphodiesterases in accounting for the cAMP-directed activity of antithrombotic agents.

  5. A novel cAMP-dependent mechanism for MRP4-mediated regulation of fibroblast migration and indicated that PKA and actin play important roles as downstream effectors.

  6. Loss of MRP4 is associated with impaired platelet activation and cAMP homeostasis

  7. Upregulation of COX-2 in lung cancer promotes overexpression of MRP4 via PGE2-dependent pathway

  8. role of MRP4 in thrombus formation

  9. NHERF3 is a key regulator of organic transport in the kidney, particularly MRP4-mediated clearance of drug molecules.

  10. Abcc4 in the stomach facilitates the oral absorption of dasatinib, and it possibly plays a similar role for other orally administered substrates, such as acetylsalicylic acid.

ABCC4 Antigen-Profil

Protein Überblick

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined\; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms.

Genbezeichner und Symbole assoziert mit ABCC4

  • ATP binding cassette subfamily C member 4 (ABCC4) Antikörper
  • multidrug resistance-associated protein 4 (LOC515333) Antikörper
  • multidrug resistance-associated protein 4 (LOC616707) Antikörper
  • multidrug resistance-associated protein 4 (LOC695407) Antikörper
  • ATP binding cassette subfamily C member 4 (abcc4) Antikörper
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 4 (Abcc4) Antikörper
  • ATP binding cassette subfamily C member 4 (Abcc4) Antikörper
  • D630049P08Rik Antikörper
  • EST170205 Antikörper
  • MOAT-B Antikörper
  • MOATB Antikörper
  • Mrp4 Antikörper

Bezeichner auf Proteinebene für ABCC4

multidrug resistance-associated protein 4 , ATP-binding cassette, sub-family C (CFTR/MRP), member 4 , ATP-binding cassette protein C4-like , multidrug resistance-associated protein 4-like , ATP-binding cassette sub-family C member 4 , MRP/cMOAT-related ABC transporter , bA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4) , canalicular multispecific organic anion transporter (ABC superfamily) , multi-specific organic anion transporter B , multispecific organic anion transporter B , ABC-tranporter , ATP-binding cassette protein C4

GENE ID SPEZIES
485523 Canis lupus familiaris
515333 Bos taurus
616707 Bos taurus
695407 Macaca mulatta
100027089 Monodelphis domestica
100050431 Equus caballus
100081616 Ornithorhynchus anatinus
100391624 Callithrix jacchus
100466405 Ailuropoda melanoleuca
100491006 Xenopus (Silurana) tropicalis
10257 Homo sapiens
239273 Mus musculus
170924 Rattus norvegicus
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