ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11) ELISA Kits

The membrane-associated protein encoded by ABCB11 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Zusätzlich bieten wir Ihnen ABCB11 Antikörper (60) und ABCB11 Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
ABCB11 8647 O95342
ABCB11 27413 Q9QY30
ABCB11 83569 O70127
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Top ABCB11 ELISA Kits auf antikoerper-online.de

Showing 5 out of 12 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 7.8 pg/mL 31.25-2000 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$910.56
Details
Maus 4.7 pg/mL 18.75-1200 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$910.56
Details
Human 78-5000 pg/mL   96 Tests Anmelden zum Anzeigen 2 bis 3 Tage
$713.90
Details
Maus
0.156-10 ng/mL   96 Tests Anmelden zum Anzeigen 2 bis 3 Tage
$867.90
Details
Ratte
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$1,029.60
Details

Weitere ELISA Kits für ABCB11 Interaktionspartner

Rainbow Trout (Oncorhynchus mykiss) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11) Interaktionspartner

  1. Data show the gene expression profiling of ABC (zeige ABCB6 ELISA Kits) transporters in seven tissues.

  2. cloned one partial and two full gene sequences, which show high degree of identity with mammalian Pgp1 (ABCB1 (zeige ABCB1 ELISA Kits)), BSEP (ABCB11) and MRP2 (ABCC2 (zeige ABCC2 ELISA Kits)) efflux transporters and found identical relative expression patterns for both liver and primary hepatocytes

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11) Interaktionspartner

  1. Case Report: compound heterozygotes for two missense mutations of the ABCB11 with a mild form of progressive familial intrahepatic cholestasis type 2.

  2. Patients with a confirmed ABCB11 or tight junction protein 2 (zeige TJP2 ELISA Kits) gene mutation (n = 7) had a minimally detectable THBA proportion (0.23-2.99% of total BAs). Three patients with an ATP8B1 (zeige ATP8B1 ELISA Kits) mutation had an elevated THBA proportion (7.51-37.26%).

  3. By these complementary approaches, a set of ten novel BSEP interaction partners was identified. With the exception of radixin (zeige RDX ELISA Kits), all other interaction partners were integral or membrane-associated proteins including proteins of the early secretory pathway and the bile acyl-CoA synthetase (zeige SLC27A5 ELISA Kits), the second to last, ER-associated enzyme of bile salt synthesis

  4. Among the Han individuals aged over 40 years in Hunan, China, genotype CC or CT of BSEP gene SNP rs2287622 may correlate with higher risk of chronic hepatitis C in comparison with genotype TT.

  5. Case Reports: late onset progressive familial intrahepatic cholestasis 2 secondary to novel ABCB11 mutations.

  6. Negative immunoreaction of BSEP was found in the majority of the progressive familial intrahepatic cholestasis (PFIC (zeige ATP8B1 ELISA Kits)) group. Nonetheless, the negative immunoreaction was demonstrated in a considerable number of the non-PFIC (zeige ATP8B1 ELISA Kits) group.BSEP immunoreaction was negative in the majority (82.4%) of PFIC2 but in none of the two patients with PFIC1 (zeige ATP8B1 ELISA Kits).

  7. The results revealed that functional impairment of BSEP predisposes the cells to altered BA disposition and is a susceptive factor to drug-induced cholestatic injury.

  8. Results identified six novel mutations (PKHD1: p.Thr777Met, p.Tyr2260Cys; ABCB11: p.Val1112Phe, c.611+1G > A, p.Gly628Trpfs*3 and NPC1 (zeige NPC1 ELISA Kits): p.Glu391Lys) for the diagnostic of inherited infantile cholestatic disorders.

  9. Report highly specific expression of BSEP and MDR3 (zeige ABCB4 ELISA Kits) in hepatocellular carcinoma.

  10. GGT levels in patients with ATP8B1 or ABCB11 deficiency varied with age. The peak GGT value was <70U/L in the 2nd~6th month of life, <60U/L in the 7th~12th month and <50U/L beyond one year

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11) Interaktionspartner

  1. Isoniazid/rifampicin administration significantly down-regulated the expression of hepatic bile acids transporters Ntcp (zeige SLC10A1 ELISA Kits) and Bsep in liver.

  2. mechanism of increased biliary lipid secretion in Bsep-/- mice is based on increased expression of the responsible canalicular transporter proteins.

  3. LKB1 (zeige STK11 ELISA Kits)/AMPK (zeige PRKAA1 ELISA Kits) and PKA control ABCB11 trafficking and polarization in hepatocytes.

  4. CA feeding of Bsep (-/-) mice increased hepatic Cyp3a11 protein levels.

  5. FXR (zeige NR1H4 ELISA Kits) regulates BSEP in an isoform-dependent and species-specific manner

  6. Ursodeoxycholic acid fed to abcb11-/- mice caused liver damage and the appearance of biliary tetra- and penta-hydroxy bile acids.

  7. Hepatic Abcb11 overexpression in mice increases the conservation of bile acids within the enterohepatic circulation.

  8. The authors show that two of these transporters, ABCB11 and ATP8B1 (zeige ATP8B1 ELISA Kits), are functional targets of miR (zeige MLXIP ELISA Kits)-33, a micro-RNA that is expressed from within an intron of SREBP-2 (zeige SREBF2 ELISA Kits).

  9. Abcb11 deficiency induces cholestasis coupled to impaired beta-fatty acid oxidation in mice.

  10. hyperosmotic cholestasis is triggered by a NADPH oxidase (zeige NOX1 ELISA Kits)-driven reactive oxygen species formation that mediates Fyn (zeige FYN ELISA Kits)-dependent retrieval of the Mrp2 (zeige ABCC2 ELISA Kits) and Bsep from the canalicular membrane, which may involve an increased cortactin (zeige CTTN ELISA Kits) phosphorylation.

ABCB11 Antigen-Profil

Beschreibung des Gens

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy.

Genbezeichner und Symbole assoziert mit ABCB11

  • ATP binding cassette subfamily B member 11 (ABCB11) Antikörper
  • bile salt export pump (LOC100489744) Antikörper
  • bile salt export pump (LOC100565276) Antikörper
  • bile salt export pump (EDI_111220) Antikörper
  • bile salt export pump (EDI_272930) Antikörper
  • bile salt export pump (abcb11) Antikörper
  • ATP binding cassette subfamily B member 11 (Abcb11) Antikörper
  • ATP-binding cassette, sub-family B (MDR/TAP), member 11 (Abcb11) Antikörper
  • ABC16 Antikörper
  • ABCB11 Antikörper
  • BRIC2 Antikörper
  • BSEP Antikörper
  • BSEP/SPGP Antikörper
  • Lith1 Antikörper
  • PFIC-2 Antikörper
  • PFIC2 Antikörper
  • PGY4 Antikörper
  • Spgp Antikörper

Bezeichner auf Proteinebene für ABCB11

ATP-binding cassette, sub-family B (MDR/TAP), member 11 , bile salt export pump , bile salt export pump-like , ABC member 16, MDR/TAP subfamily , ATP-binding cassette sub-family B member 11 , progressive familial intrahepatic cholestasis 2 , sister p-glycoprotein , ATP-binding cassette, sub-family B, member 11 , sister of P-glycoprotein , liver bile salt export pump

GENE ID SPEZIES
424170 Gallus gallus
470717 Pan troglodytes
488390 Canis lupus familiaris
531150 Bos taurus
100024107 Monodelphis domestica
100052359 Equus caballus
100083318 Ornithorhynchus anatinus
100404882 Callithrix jacchus
100454135 Pongo abelii
100473353 Ailuropoda melanoleuca
100489744 Xenopus (Silurana) tropicalis
100518154 Sus scrofa
100543935 Meleagris gallopavo
100565276 Anolis carolinensis
100590891 Nomascus leucogenys
5879080 Entamoeba dispar SAW760
5914265 Entamoeba dispar SAW760
100136688 Oncorhynchus mykiss
100337637 Cavia porcellus
8647 Homo sapiens
27413 Mus musculus
100008767 Oryctolagus cuniculus
83569 Rattus norvegicus
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