anti-ADP-Ribosylation Factor-Like 13B (ARL13B) Antikörper

ARL13B encodes a member of the ADP-ribosylation factor-like family. Zusätzlich bieten wir Ihnen ARL13B Proteine (6) und ARL13B Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ARL13B 304037  
ARL13B 200894 Q3SXY8
ARL13B 68146 Q640N2
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Top anti-ARL13B Antikörper auf antikoerper-online.de

Showing 10 out of 27 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-ARL13B Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>721_B cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-ARL13B Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Jurkat cell lysate WB Suggested Anti-ARL13B <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500 <br /> Positive Control: Jurkat cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Meerschweinchen Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western Blot: ARL13B Antibody [NBP2-15463] - Sample (30 ug of whole cell lysate) A: 293T 10% SDS PAGE gel, diluted at 1:1000. Immunohistochemistry-Paraffin: ARL13B Antibody [NBP2-15463] - Immunohistochemical analysis of paraffin-embedded U87 xenograft, using antibody at 1:500 dilution. 0.1 mL Anmelden zum Anzeigen 3 bis 6 Tage
341,00 €
Details
Human Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
Details
Human Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
459,65 €
Details
Human Kaninchen Unkonjugiert IF, WB Western blot analysis of extracts of LO2 and U87 cells, using ARL13B antibody. 100 μL Anmelden zum Anzeigen 12 Days
392,86 €
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Immunohistochemistry-Paraffin: ARL13B Antibody [NBP2-14312] Staining of human testis shows strong cytoplasmic positivity in cells in seminiferus ducts. 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Human Maus Unkonjugiert ELISA, WB Western Blot detection against Immunogen (36.74 KDa) . 200 μL Anmelden zum Anzeigen 7 bis 8 Tage
369,60 €
Details
Human Kaninchen Unkonjugiert WB ARL13B antibody used at 1 ug/ml to detect target protein. 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
460,89 €
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ARL13B Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Rat (Rattus)


Human ,
,
,
Mouse (Murine)


Am meisten referenzierte anti-ARL13B Antikörper

  1. Mammalian Monoclonal ARL13B Primary Antibody für ISt, IHC - ABIN1304542 : Banda, McKinsey, Germain, Carter, Anderson, Grabel: Cell polarity and neurogenesis in embryonic stem cell-derived neural rosettes. in Stem cells and development 2015 (PubMed)
    Show all 14 Pubmed References

  2. Cow (Bovine) Polyclonal ARL13B Primary Antibody für WB - ABIN2785090 : Fan, Esmail, Ansley, Blacque, Boroevich, Ross, Moore, Badano, May-Simera, Compton, Green, Lewis, van Haelst, Parfrey, Baillie, Beales, Katsanis, Davidson, Leroux: Mutations in a member of the Ras superfamily of small GTP-binding proteins causes Bardet-Biedl syndrome. in Nature genetics 2004 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen ARL13B Interaktionspartner

Zebrafish ADP-Ribosylation Factor-Like 13B (ARL13B) Interaktionspartner

  1. loss of Arl13b leads to slow photoreceptor degeneration, but can be exacerbated by the loss of vangl2 (zeige VANGL2 Antikörper). Importantly, the data show that Arl13b can genetically and physically interact with Vangl2 (zeige VANGL2 Antikörper) and this association is important for normal photoreceptor structure.

  2. Arl13b is an important effector of ciliary membrane biogenesis and ciliary length regulation.

  3. Cilia localization is essential for in vivo functions of the Joubert syndrome protein arl13b.

Human ADP-Ribosylation Factor-Like 13B (ARL13B) Interaktionspartner

  1. the results show that palmitoylation plays a unique and critical role in controlling the localization, stability, abundance, and thus function of ARL13b. Pharmacological manipulation of protein palmitoylation may be a strategy to alter cilia function.

  2. Our results show how Arl13b participates in Hedgehog (zeige SHH Antikörper) pathway activation in gastric cancer

  3. Reduced primary cilia length and altered Arl13b expression are associated with deregulated chondrocyte Hedgehog (zeige SHH Antikörper) signaling in alkaptonuria (zeige HGD Antikörper).

  4. ARL13B regulates IFT-A-mediated retrograde protein trafficking within cilia through its interaction with INPP5E.

  5. Biochemical characterization of purified mammalian ARL13B protein indicates that it is an atypical GTPase (zeige RACGAP1 Antikörper) and ARL3 guanine nucleotide exchange factor (zeige RASGRF1 Antikörper) (GEF (zeige SLC2A4RG Antikörper)).(

  6. Thus our data identify a novel ARL13B variant that causes JS and retinopathy and suggest an extension of the phenotypic spectrum of ARL13B mutations to obesity.

  7. We conclude that MKS/NPHP modules comprise a TZ barrier to ARL-13 diffusion, whereas IFT genes predominantly facilitate ARL-13 ciliary entry and/or retention via active transport mechanisms.

  8. X-ray crystallography of Arl13B demonstrates involvement of mutations R79Q and R200C in stabilizing intramolecular interactions.

  9. Arl13b acts as the all-rounder in cilia formation and signaling (Review).

  10. findings indicate that ARL13B, INPP5E, PDE6D (zeige PDE6D Antikörper), and CEP164 (zeige CEP164 Antikörper) form a distinct functional network that is involved in JBTS and NPHP but independent of the ones previously defined by NPHP and MKS (zeige MKS1 Antikörper) proteins

Mouse (Murine) ADP-Ribosylation Factor-Like 13B (ARL13B) Interaktionspartner

  1. Arl13b dysfunction resulted in hennin cell stagnation due to poor growth factor signaling and impaired detection of extracellular electrical gradients.

  2. Biochemical characterization of purified mammalian ARL13B protein indicates that it is an atypical GTPase (zeige RACGAP1 Antikörper) and ARL3 guanine nucleotide exchange factor (zeige ARHGEF12 Antikörper) (GEF (zeige ARHGEF2 Antikörper)).(

  3. To investigate whether Arl13b has a role in ciliogenesis in mammalian kidney and whether loss of function of Arl13b leads to cystic kidneys in mammals, we generated a mouse model with kidney-specific conditional knockout of Arl13b Deletion of Arl13b in the distal nephron at the perinatal stage led to a cilia biogenesis defect and rapid kidney cyst formation

  4. The authors show that the ciliary G-protein Arl13B, mutated in Joubert syndrome, is the guanine nucleotide exchange factor for Arl3, and its function is conserved in evolution

  5. A new role for Arl13b in actin cytoskeleton remodeling through the interaction with Myh9 (zeige MYH9 Antikörper).

  6. Early neuroepithelial deletion of ciliary Arl13b reversed the apical-basal polarity of radial progenitors & caused aberrant neuronal placement. Arl13b signaling in primary cilia is crucial for initial formation of a polarized radial glial scaffold.

  7. guidance cue receptors essential for interneuronal migration localize to interneuronal primary cilia, but their concentration and dynamics are altered in the absence of Arl13b

  8. By deleting Arl13b in mouse, we induced low-level constitutive GliA function at specific developmental stages and defined a crucial period prior to E10.5 when shifts in the level of GliA cause cells to change their fate

  9. Study shows the cilia protein Arl13b is required for left right axis specification as its absence results in heterotaxia; the defect originates in the node where Cerl2 (zeige DAND5 Antikörper) is not downregulated and asymmetric expression of Nodal is not maintained resulting in symmetric expression of both genes.

  10. The role of Arl13b in ciliogenesis and it's interaction with Smo and Shh (zeige SHH Antikörper) proteins.Arl13b regulates the ciliary entry of Smo.

ARL13B Antigen-Profil

Protein Überblick

This gene encodes a member of the ADP-ribosylation factor-like family. The encoded protein is a small GTPase that contains both N-terminal and C-terminal guanine nucleotide-binding motifs. This protein is localized in the cilia and plays a role in cilia formation and in maintenance of cilia. Mutations in this gene are the cause of Joubert syndrome 8. Alternate splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit ARL13B

  • ADP-ribosylation factor-like 13B (Arl13b) Antikörper
  • ADP-ribosylation factor-like 13B (ARL13B) Antikörper
  • ADP-ribosylation factor-like 13B (arl13b) Antikörper
  • ADP-ribosylation factor-like 13b (arl13b) Antikörper
  • A530097K21Rik Antikörper
  • A930014M17Rik Antikörper
  • Arl2l1 Antikörper
  • C530009C10Rik Antikörper
  • chunp6872 Antikörper
  • fc23g07 Antikörper
  • hnn Antikörper
  • JBTS8 Antikörper
  • MGC185757 Antikörper
  • wu:fc23g07 Antikörper
  • zgc:123149 Antikörper

Bezeichner auf Proteinebene für ARL13B

ADP-ribosylation factor-like protein 13B , ADP-ribosylation factor-like 2-like 1 , ADP-ribosylation factor-like 13B , ADP-ribosylation factor-like protein 13B-like , ADP-ribosylation factor-like protein 2-like 1 , ARL2-like protein 1 , protein scorpion , scorpion , un-named hi459 , unm hi459

GENE ID SPEZIES
304037 Rattus norvegicus
418431 Gallus gallus
460534 Pan troglodytes
487934 Canis lupus familiaris
512781 Bos taurus
694959 Macaca mulatta
100124913 Xenopus (Silurana) tropicalis
100413286 Callithrix jacchus
100456801 Pongo abelii
100467626 Ailuropoda melanoleuca
100600917 Nomascus leucogenys
286784 Danio rerio
200894 Homo sapiens
68146 Mus musculus
Ausgewählte Anbieter für anti-ARL13B (ARL13B) Antikörper
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