anti-Cyclin E1 Antikörper

Protein Überblick

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis. This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in cell-cycle regulated histone gene expression and plays a critical role in promoting cell-cycle progression in the absence of pRB. Two alternatively spliced transcript variants of this gene, which encode distinct isoforms, have been described. Two additional splice variants were reported but detailed nucleotide sequence information is not yet available.

Alternative names and synonyms associated with Cyclin E1 (CCNE1)

• cyclin E1 (CCNE1) Antikörper
• cyclin E1 (ccne1) Antikörper
• cyclin E1 (Ccne1) Antikörper
• cyclin E1 L homeolog (ccne1.L) Antikörper
• cyclin E1 S homeolog (ccne1.S) Antikörper

• AW538188 Antikörper
• Ccne Antikörper
• CCNE1 Antikörper
• cyce Antikörper
• CycE1 Antikörper
• Alle Synonyme
• cyce2 Antikörper
• cycE3 Antikörper
• CYCLE Antikörper
• cyclinE Antikörper
• fa18e07 Antikörper
• wu:fa18e07 Antikörper

Bezeichner auf Proteinebene für anti-Cyclin E1 (CCNE1) Antikörper

cyclin E1 , G1/S-specific cyclin-E1 , G1/S-specific cyclin-E1-like , g1/S-specific cyclin-E1-like , cyclin Es , cyclin Et , cyclin E , G1/S-specific cyclin-E2 , cyclin-E-1 , G1/S-specific cyclin-E3 , cyclin E3