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anti-Mouse (Murine) WNT7A Antikörper:
anti-Human WNT7A Antikörper:
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Human Polyclonal WNT7A Primary Antibody für IHC, IHC (p) - ABIN4366196
Yoshioka, King, Ran, Okuda, MacLean, McAsey, Sugino, Brard, Watabe, Hayashi: WNT7A regulates tumor growth and progression in ovarian cancer through the WNT/β-catenin pathway. in Molecular cancer research : MCR 2012
Show all 4 Pubmed References
Wnt7a has a role in postmenstrual regeneration and proliferation of endometrial glands and luminal epithelium in primates
experiments indicate that Reck (zeige RECK Antikörper) and Gpr124 (zeige GPR124 Antikörper) are part of the cell surface protein (zeige CD28 Antikörper) complex that transduces Wnt7a- and Wnt7b (zeige WNT7B Antikörper)-specific signals in mammalian CNS epithelial cells to promote angiogenesis and regulate the BBB (zeige ALMS1 Antikörper)
WNT7a is sufficient to restore post-pubertal endometrial gland formation.
we found that post-ejaculated semen from fertile wild-type males was solidified and the sperm were entrapped in Wnt7aCre/+;Esr1f/f uteri, compared to the watery semen (liquefied) found in Esr1f/f controls.Kallikrein-related peptidases 3 (KLK3 (zeige PSA Antikörper)) and other kallikrein (zeige KLK1 Antikörper)-related peptidases from male prostate glands are responsible for semen liquefaction by cleaving gel-forming proteins
Data show that the WIF domain of Wnt Inhibitory Factor 1 (WIF1 (zeige WIF1 Antikörper)) is bound by C-terminal domains of Wnt (zeige WNT2 Antikörper) proteins Wnt5a (zeige WNT5A Antikörper) and Wnt7a at two sites.
Wnt7a is a novel regulator of ventral midbrain neurogenesis and dopaminergic neuron axon growth and guidance.
Truncated Wnt7a lacking the conserved palmitoylation sites retains full biological activity in skeletal muscle.
epithelial Wnt7a and Wnt7b (zeige WNT7B Antikörper) are possible ligands of Fzd-mediated beta-catenin (Ctnnb1 (zeige CTNNB1 Antikörper))-dependent (canonical) Wnt (zeige WNT2 Antikörper) signaling in the adjacent undifferentiated periotic mesenchyme of fibrocytes in the murine inner ear
Binding of Wnt7a to Fzd7 (zeige FZD7 Antikörper) leads to an activation of noncanonical Wnt (zeige WNT2 Antikörper) signaling, resulting in directed myogenic stem cell migration and enhanced engraftment.
Wnt7a triggers melanocyte stem cell differentiation through beta-catenin (zeige CTNNB1 Antikörper) activation, and Kitl (zeige KITLG Antikörper) might induce following migration of melanoblasts to epidermis
Wnt7a exercised critical control over multiple steps of neurogenesis by regulating genes involved in both cell cycle control and neuronal differentiation.
This report deals with linkage studies and exome sequencing, disclosing a novel variant in WNT7A, c.934G>A (p.Gly312Ser), as the cause of this Santos syndrome.
Demonstrate a significant change in miRNA profile dependent on the assisted reproductive technology outcome affecting Wnt (zeige WNT2 Antikörper) pathway.
A homozygous novel WNT7A mutation was identified in a child with Al-Awadi-Raas-Rothschild syndrome accompanied by dental abnormalities and his parents with dental abnormalities.
Activation of the WNT (zeige WNT2 Antikörper)/CTNBB1 pathway via WNT7A might play a role in PTC (zeige F9 Antikörper) development.
Results show that Wnt7a expression is significantly upregulated in epithelial cells of ovarian cancer which correlates with STAT4 (zeige STAT4 Antikörper) expression and provide evidence that STAT4 (zeige STAT4 Antikörper) promotes ovarian cancer metastasis via tumor-derived Wnt7a-induced activation of cancer-associated fibroblasts.
WNT7A is a direct target of miR (zeige MLXIP Antikörper)-15b in ovarian cancer cell line.
The findings presented in this fetus are compatible with diagnosis of Al-Awadi-Raas-Rothschild syndrome , expanding the mutational spectrum of limb malformations arising from defects in WNT7A
Wnt7a is involved in the transformation of the retinal pigment epithelium.
Wnt7a overexpression is associated with an unfavorable prognosis and that positive Wnt7a may be an independent prognosis factor influencing OS and DFS (zeige FST Antikörper) prediction in colorectal cancer patients.
identified Iloprost, a prostacyclin analog, which initiates downstream signaling cascades similar to that of Wnt7a, as a novel inducer of cellular senescence, presenting potential future clinical translational strategies
Wnt7a haplotype 1 had the highest haplotype frequencies and was highly significantly associated with body height, body weight, chest width and height at hip cross.
This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is involved in the development of the anterior-posterior axis in the female reproductive tract, and also plays a critical role in uterine smooth muscle pattering and maintenance of adult uterine function. Mutations in this gene are associated with Fuhrmann and Al-Awadi/Raas-Rothschild/Schinzel phocomelia syndromes.
, wingless-type MMTV integration site family, member 7A
, postaxial hemimelia
, proto-oncogene Wnt7a protein
, wingless-related MMTV integration site 7A
, wingless-type MMTV integration site 7A
, Protein Wnt-7a
, wnt-1 related (wnt-7a), wingless-type MMTV integration site family
, protein Wnt-7a-like