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UVRAG Produkte

(UV Radiation Resistance Associated Gene (UVRAG))

Kategorien

This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer. [provided by RefSeq, Jul 2008].

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Ausgewählte UVRAG Kategorien

UVRAG Antikörper

High quality antibodies with extensive validation data.

UVRAG Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene UVRAG Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (1)
  • (4)
Kat. Nr. ABIN6150044
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF, IHC
Validierungen
  • (4)
Kat. Nr. ABIN7175178
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, IF, IHC (p)
Validierungen
  • (7)
  • (3)
Kat. Nr. ABIN388586
Menge 400 μL
Datenblatt Datenblatt

Empfohlene UVRAG ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6201850
Menge 96 tests
Datenblatt Datenblatt

Empfohlene UVRAG Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1324875
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1324874
Menge 25 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3096275
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren UVRAG Produkten

Aikawa, Nakajima, Karimine, Nozawa, Minowa-Nozawa, Toh, Yamada, Nakagawa: "NLRX1 Negatively Regulates Group A Streptococcus Invasion and Autophagy Induction by Interacting With the Beclin 1-UVRAG Complex." in: Frontiers in cellular and infection microbiology, Vol. 8, pp. 403, (2019) (PubMed).

Chen, Wu, Sang, Wang, Zong, Sun, Liu, Zhao: "The lncRNA HULC functions as an oncogene by targeting ATG7 and ITGB1 in epithelial ovarian carcinoma." in: Cell death & disease, Vol. 8, Issue 10, pp. e3118, (2018) (PubMed).

Sun, Li, Zhang, Chen, Zhang, Li, Deng, Qian, Jiao, Ji, Li, Wu, Yu, Feng, Zhu: "Acetylation of Beclin 1 inhibits autophagosome maturation and promotes tumour growth." in: Nature communications, Vol. 6, pp. 7215, (2015) (PubMed).

Wei: "Autophagic induction of amyotrophic lateral sclerosis-linked Cu/Zn superoxide dismutase 1 G93A mutant in NSC34 cells." in: Neural regeneration research, Vol. 9, Issue 1, pp. 16-24, (2014) (PubMed).

Armstrong, Corazzari, Martin, Pagliarini, Falasca, Hill, Ellis, Al Sabah, Redfern, Fimia, Piacentini, Lovat: "Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 8, pp. 2216-26, (2011) (PubMed).

Sun, Zhang, Fan, Wong, Ding, Chen, Zhong: "The RUN domain of rubicon is important for hVps34 binding, lipid kinase inhibition, and autophagy suppression." in: The Journal of biological chemistry, Vol. 286, Issue 1, pp. 185-91, (2011) (PubMed).

Bodemann, Orvedahl, Cheng, Ram, Ou, Formstecher, Maiti, Hazelett, Wauson, Balakireva, Camonis, Yeaman, Levine, White: "RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly." in: Cell, Vol. 144, Issue 2, pp. 253-67, (2011) (PubMed).

Neely, Green, LaFerla: "Presenilin is necessary for efficient proteolysis through the autophagy-lysosome system in a ?-secretase-independent manner." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 8, pp. 2781-91, (2011) (PubMed).

Sun, Westphal, Wong, Tan, Zhong: "Rubicon controls endosome maturation as a Rab7 effector." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 45, pp. 19338-43, (2010) (PubMed).

Gao, Kang, Liao, Ding, Gambotto, Watkins, Liu, Stolz, Yin: "Biochemical isolation and characterization of the tubulovesicular LC3-positive autophagosomal compartment." in: The Journal of biological chemistry, Vol. 285, Issue 2, pp. 1371-83, (2010) (PubMed).

Synonyme und alternative Namen zu UVRAG

UV radiation resistance associated (UVRAG), UV radiation resistance associated gene (Uvrag), UV radiation resistance associated gene (uvrag), UV radiation resistance associated (Uvrag), UV radiation resistance associated S homeolog (uvrag.S), UV radiation resistance associated L homeolog (uvrag.L), UV radiation resistance associated (uvrag), UV-resistance associated gene (Uvrag), 9530039D02Rik, AI648770, BB124205, CG6116, DHTX, Dmel\\CG6116, MGC81810, MGC131135, p63, uvrag, UVRAG, Uvrag1, Uvragl, VPS38, zgc:56164

Bezeichner auf Proteinebene für UVRAG

  • UV radiation resistance-associated gene protein
  • beclin 1 binding protein
  • disrupted in heterotaxy
  • UV radiation resistance associated
  • UV radiation resistance associated gene
  • UV radiation resistance-associated gene protein-like
  • CG6116-PA
  • CG6116-PB
  • Uvrag-PA
  • Uvrag-PB
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