Der Schaf Polyklonal anti-VAMP1/VAMP2 Antikörper (ABIN306588) detektiert spezifisch VAMP1/VAMP2 in IP und WB.
Dieser Antikörper reagiert spezifisch mit Proben aus Human und Ratte.
Kurzübersicht für VAMP1/VAMP2 Antikörper (full length) (ABIN306588)
Target
VAMP1/VAMP2
(Vesicle-Associated Membrane Protein 1/2 (Synaptobrevin 1/2) (VAMP1/VAMP2))
Reaktivität
Human, Ratte
Wirt
Schaf
Klonalität
Polyklonal
Applikation
Immunoprecipitation (IP), Western Blotting (WB)
Bindungsspezifität
full length
Verwendungszweck
Sheep anti Human Vesicle Associated Membrane Protein (VAMP 1/2)
Kreuzreaktivität
Human
Produktmerkmale
Vesicle-associated membrane protein 2 is essential for cAMP-regulated exocytosis. VAMP (also know as synaptobrevin) is part of the synaptic vesicle docking and fusion complex and plays a central role in neuroexocytosis. Two VAMP (vesicle-associated membrane protein) isoforms are expressed in the nervous system and are differently distributed among the specialized parts of the tissue. VAMP-1 and -2 are present in all tissues tested, including kidney, adrenal gland, liver, pancreas, thyroid, heart, and smooth muscle. The two isoforms are differentially expressed in various tissues and their level may depend on differentiation. VAMP-1 is restricted to exocrine pancreas and to kidney tubular cells, whereas VAMP-2 is the predominant isoform present in Langerhans islets and in glomerular cells. Both isoforms show a patchy vesicular intracellular distribution in confocal microscopy. Evidence for the importance of neuronal VAMPproteins in the physiology of all cells is indicated.
Aufreinigung
Ammonium Sulfate Precipitation
Immunogen
Full length VAMP1/2 protein
Isotyp
IgG
Applikationshinweise
Applications: Western Blotting, Immunoprecipitation
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
phosphate buffered saline with 0.08 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
Target
VAMP1/VAMP2
(Vesicle-Associated Membrane Protein 1/2 (Synaptobrevin 1/2) (VAMP1/VAMP2))
Andere Bezeichnung
Vesicle Associated Membrane Protein (VAMP 1/2)
Hintergrund
Sheep anti vesicle associated membrane protein 1 and 2, VAMP 1 and 2, VAMP1/2, VAMP 1/2, VAMP-1/2, Synaptobrevin 1 and 2