anti-SEMA4C (SEMA4C) Antikörper

Human Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4C (SEMA4C) Interaktionspartner

1. ectopic expression of miR (zeige MLXIP Antikörper)-25-3p reversed the epithelial-mesenchymal transition phenotype and sensitized cisplatin-resistant cervical cancer cells to cisplatin via targeting Sema4C

2. Data show that G-protein-coupled receptor (zeige ADRA1A Antikörper) kinase-interacting protein (zeige CIB1 Antikörper) 1 (GIT1) and semaphorin 4C (SEMA4C) were found to have putative microRNA miR (zeige MLXIP Antikörper)-138 binding sites in their 3' untranslated region (3'UTRs).

3. Suggest that up-regulation of miR (zeige MLXIP Antikörper)-125b or targeting Sema4C could serve as novel approaches to reverse chemotherapy resistance in breast cancers.

4. Data suggest that Erbin (zeige ERBB2IP Antikörper) can interact with Sema4C, and co-expression of Erbin (zeige ERBB2IP Antikörper) blocks the process of Sema4C-induced epithelial-mesenchymal transition.

5. There is a high expression of Sema4C in esophageal cancer, gastric cancer and rectal cancer, and expression is strongly correlated with lymphatic metastasis.

6. High Sema4C is associated with epithelial-mesenchymal transition and renal fibrosis.

Mouse (Murine) Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4C (SEMA4C) Interaktionspartner

1. Follicular T helper cells use Semaphorin 4C as a guidance receptor to sense germinal center-expressed Plexin B2 (zeige PLXNB2 Antikörper).

2. we demonstrate that Sema4C is critical for optimal regulatory cytokine production in CD138 (zeige SDC1 Antikörper)(+) B cells.

3. Sema4C-Plexin B2 (zeige PLXNB2 Antikörper) signalling regulates ureteric branching

4. We have identified here Sema4C and Sema4G (zeige SEMA4G Antikörper) as candidate ligands for Plexin-B2 (zeige PLXNB2 Antikörper)

5. Plexin-B2 (zeige PLXNB2 Antikörper) and Sema4C are potential regulators of the vascular and endocrine system.

6. Results suggest a putative role of Sema4C during neurogenesis both in vivo and in vitro.

7. Sema4C-mediated interaction among myoblasts plays an important role in terminal myogenic differentiation

8. Sema4C promotes terminal myogenic differentiation in a p38 MAPK (zeige MAPK14 Antikörper)-dependent manner.