anti-Podocalyxin-Like (PODXL) Antikörper

Bezeichnung:: anti-Podocalyxin-Like Antikörper (PODXL)

Auf www.antikoerper-online.de finden Sie aktuell 406 Podocalyxin-Like (PODXL) Antikörper von 29 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Podocalyxin-Like Kits (60) und Podocalyxin-Like Proteine (27) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 502 Podocalyxin-Like Produkte verfügbar.

Synonyme:: AW121214, cPCLP1, fc18d02, Gp135, Gp200, Ly102, MEP21, PC, PCLP, PCLP-1, PCLP1, podocalyxin, Podxl, wu:fc18d02

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	PODXL	5420	O00592
	PODXL	27205	Q9R0M4
	PODXL	192181	Q9WTQ2
Alle Spezies anzeigen Weitere Synonyme anzeigen

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Verknüpfte Pathways mit anti-Podocalyxin-Like Antikörper

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Weitere Produktkategorien zu Podocalyxin-Like Antikörper

Am meisten referenzierte anti-Podocalyxin-Like Antikörper

Mouse (Murine) Polyclonal PODXL Primary Antibody für CyTOF, FACS - ABIN4899592 : Kumagai, Baldwin, Aoudjit, Nezvitsky, Robins, Jiang, Takano: Protein tyrosine phosphatase 1B inhibition protects against podocyte injury and proteinuria. in The American journal of pathology 2014 (PubMed)
Show all 17 Pubmed References
Human Polyclonal PODXL Primary Antibody für CyTOF, FACS - ABIN4899749 : Ylöstalo, Bazhanov, Prockop: Reversible commitment to differentiation by human multipotent stromal cells in single-cell-derived colonies. in Experimental hematology 2008 (PubMed)
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Human Monoclonal PODXL Primary Antibody für ICC, FACS - ABIN151343 : Badcock, Pigott, Goepel, Andrews: The human embryonal carcinoma marker antigen TRA-1-60 is a sialylated keratan sulfate proteoglycan. in Cancer research 1999 (PubMed)
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Human Polyclonal PODXL Primary Antibody für ICC, IF - ABIN4346616 : Cheung, Davis, Lee, Pang, Nagrani, Rennert, Chan: Methylation of an intronic region regulates miR-199a in testicular tumor malignancy. in Oncogene 2011 (PubMed)
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Human Monoclonal PODXL Primary Antibody für CyTOF, FACS - ABIN4899748 : Ronconi, Sagrinati, Angelotti, Lazzeri, Mazzinghi, Ballerini, Parente, Becherucci, Gacci, Carini, Maggi, Serio, Vannelli, Lasagni, Romagnani, Romagnani: Regeneration of glomerular podocytes by human renal progenitors. in Journal of the American Society of Nephrology : JASN 2009 (PubMed)
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Human Monoclonal PODXL Primary Antibody für ICC, FACS - ABIN152150 : Matin, Walsh, Gokhale, Draper, Bahrami, Morton, Moore, Andrews: Specific knockdown of Oct4 and beta2-microglobulin expression by RNA interference in human embryonic stem cells and embryonic carcinoma cells. in Stem cells (Dayton, Ohio) 2004 (PubMed)
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Human Monoclonal PODXL Primary Antibody für FACS, ICC - ABIN4346634 : Schopperle, Kershaw, DeWolf: Human embryonal carcinoma tumor antigen, Gp200/GCTM-2, is podocalyxin. in Biochemical and biophysical research communications 2002 (PubMed)
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Mouse (Murine) Monoclonal PODXL Primary Antibody für CyTOF, FACS - ABIN4899591 : Maltby, Hughes, Zbytnuik, Paulson, McNagny: Podocalyxin selectively marks erythroid-committed progenitors during anemic stress but is dispensable for efficient recovery. in Experimental hematology 2008 (PubMed)
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Polyclonal PODXL Primary Antibody für WB - ABIN540335 : Kelley, Huntsman, McNagny, Roskelley, Hsi: Podocalyxin: a marker of blasts in acute leukemia. in American journal of clinical pathology 2005 (PubMed)
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Human Monoclonal PODXL Primary Antibody für CyTOF, FACS - ABIN5503174 : Kim, Kim, Jung, Kim, Kwon, Son, Jang, Choi, Park, Park, Han, Lee, Cho, Bae: Comparative proteomic analysis of human somatic cells, induced pluripotent stem cells, and embryonic stem cells. in Stem cells and development 2012 (PubMed)
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Weitere Antikörper gegen Podocalyxin-Like Interaktionspartner

Human Podocalyxin-Like (PODXL) Interaktionspartner

Data suggest that targeting the podocalyxin-like protein (PODXL)/RUN and FYVE domain containing 1 (RUFY1) complex might improve cancer therapy.
s-Podxl is independently associated with carotid IMT and might be used as a novel biomarker for cardiovascular disease.
Results show high podocalyxin expression in prostate cancer and can be used as a tumor marker for disease progression and patients stratification.
Summary of the structural features of podocalyxin glycoforms from embryonic and induced pluripotent stem cells (review).
This set of symptoms strikingly mimics previously reported mouse Podxl(-/-) embryos, emphasizing the essential function of PODXL in mammalian kidney development and highlighting this patient as a human PODXL-null model.
These results indicate that PcMab-47 is useful in detecting podocalyxin of oral cancers for immunohistochemical analysis
expression of PODXL associates with TAZ downstream gene expression. Suppression of PODXL induces phosphorylation of LATS1 and TAZ, and is accompanied with a decrease in TAZ protein expression. We speculate that changes in actin cytoskeleton may participate in PODXL-mediated TAZ signaling.
Results show that PODXL performs as a tumor promoter in gastric tumor cells (GC). PODXL is a target gene of miR-509-3-5P; the ectopic expression of miR-509-3-5P in GC cell lines inhibits the colony, motility and invasion abilities via negatively targeting PODXL.
Podocalyxin as a major pluripotent marker and novel keratan sulfate proteoglycan in human embryonic and induced pluripotent stem cells.
A novel frameshift mutation in PODXL seems to be the likely cause of ARJP in this family.
These findings suggest a potential functional link in colorectal cancer between PODXL, EGFR and BRAF.
PODXL enhances motility and invasiveness through an increase in gelsolin-actin interactions in cell protrusions.
Results identify an anti-metastatic miRNA, miR-5100, that decreases the metastatic ability of pancreatic cancer partially by suppressing expression of PODXL.
Results indicate that urinary podocalyxin is not only an early marker but also a treatment target for diabetic nephropathy (DN).
Obese subjects showed evidence of renal alteration through the detection of a higher number of urinary podocalyxin positive cells.
Data show that both mucin16 (MUC16) and podocalyxin (PODXL)-E-selectin-mediated interactions are mechanically stronger than like L-selectin interactions at the single-molecule level.
In gastric cancer, PODXL expression by the polyclonal antibody HPA2110 is an independent marker of poor prognosis.
PCX promotes cisplatin chemoresistance in osteosarcoma cells through a PI3Kdependent mechanism.
EZR, CLIC5 and PODXL are overexpressed in hepatocellular carcinoma and may have a role in cell migration and invasiveness
PODXL up-regulates the expression level of Bmi1 in OTSCC cells.

Mouse (Murine) Podocalyxin-Like (PODXL) Interaktionspartner

Podocalyxin-like protein 1 is a relevant marker for human c-kit(pos) cardiac stem cells.(
Podxl-KO led to heightened G-CSF activation of Rap1a(GTP), and Rap1a(GTP) inhibition attenuated Podxl-KO neutrophil migration. Studies have revealed novel roles for Podxl as an important modulator of neutrophil and monocyte formation and of Rap1a activation during stress hematopoiesis.
Podxl-overexpression in neural stem/progenitor cells leads to an up-regulation of Annexin A2.
when endogenous podocalyxin was removed from highly metastatic 4T1 mammary tumor cells there was a decrease in collective invasion . Podocalyxin is a tumor cell-intrinsic regulator of experimental collective tumor cell invasion and tumor budding.
Podocalyxin has a role in glioblastoma multiforme cell invasion and proliferation via beta-catenin signaling
Loss of podocalyxin from the lung vasculature results in changes to the lung structure and function including increased lung volume when inflated under constant pressure (25 cm H2O) and changes to the matrix composition.
CTGF is an important mediator of high glucose-induced podocyte damage and decreases the protein level of podocalyxin by the ERK1/2 pathway.
platelet Podxl is involved in the control of hemostasis acting as a platelet co-stimulator, likely due to its pro-adhesive properties
Full-length recombinant murine podocalyxin recruits NHERF-1 to the apical domain. Ectopic expression in human & canine epithelial cells leads to microvilli formation on an apical domain extending laterally to the junctional complexes.
Podocalyxin plays multiple roles in neural development
PODXL may act as a costimulator of agonists in the activation of platelets and formation of a stable thrombus.
Data show that in podocalyxin-deficient mice, the thickness of the main carotid artery is significantly increased, and there is an increased number of choroidal capillaries lining the ventricular spaces.
Podocalyxin mRNA was widely expressed at least from E14, the first age we studied, and expression remained high until adulthood
In mice expressing an Erythropoietin receptor allele, compromised erythropoietin-induced podocalyxin expression correlated with enucleated red cells in bone marrow.
PODXL(hi)/CD49f(hi) MSCs were less prone to produce lethal pulmonary emboli
Podocalyxin selectively marks erythroid-committed progenitors during anemic stress but is dispensable for efficient recovery.
Podocalyxin is required for normal kidney function

Podocalyxin-Like (PODXL) Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.

Alternative names and synonyms associated with Podocalyxin-Like (PODXL)

podocalyxin like (PODXL) Antikörper
podocalyxin-like (Podxl) Antikörper
podocalyxin-like (podxl) Antikörper
podocalyxin like (Podxl) Antikörper

AW121214 Antikörper
cPCLP1 Antikörper
fc18d02 Antikörper
Gp135 Antikörper
Gp200 Antikörper
Ly102 Antikörper
MEP21 Antikörper
PC Antikörper
PCLP Antikörper
PCLP-1 Antikörper
PCLP1 Antikörper
podocalyxin Antikörper
Podxl Antikörper
wu:fc18d02 Antikörper

Bezeichner auf Proteinebene für PODXL

GCTM-2 antigen , podocalyxin , podocalyxin-like protein 1 , thrombomucin , podocalyxin-like , PC-like protein 1 , Podocalyxin-like protein 1 , podocalyxin-like protein 1-like

GENE ID	SPEZIES
5420	Homo sapiens
27205	Mus musculus
192181	Rattus norvegicus
395755	Gallus gallus
472604	Pan troglodytes
482252	Canis lupus familiaris
563365	Danio rerio
616366	Bos taurus
100462597	Pongo abelii
100512201	Sus scrofa
100727578	Cavia porcellus
100009552	Oryctolagus cuniculus
101106679	Ovis aries

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Show all anti-Podocalyxin-Like (PODXL) Antikörper with Pubmed References

Human Podocalyxin-Like (PODXL) Interaktionspartner

Mouse (Murine) Podocalyxin-Like (PODXL) Interaktionspartner

Beschreibung des Gens

Alternative names and synonyms associated with Podocalyxin-Like (PODXL)

Bezeichner auf Proteinebene für PODXL