anti-Oxidative-Stress Responsive 1 (OXSR1) Antikörper

Bezeichnung:: anti-Oxidative-Stress Responsive 1 Antikörper (OXSR1)

Auf www.antikoerper-online.de finden Sie aktuell 119 Oxidative-Stress Responsive 1 (OXSR1) Antikörper von 18 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Oxidative-Stress Responsive 1 Proteine (9) und Oxidative-Stress Responsive 1 Kits (7) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 150 Oxidative-Stress Responsive 1 Produkte verfügbar.

Synonyme:: 2210022N24Rik, 2810422B09Rik, AI462649, AW209236, C20orf111, dJ1183I21.1, HSPC207, mKIAA1101, odd1, osr1, Perit1, zgc:55494, zgc:77321

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	OXSR1	9943	O95747
	OXSR1	108737	Q6P9R2
	OXSR1	316064
Alle Spezies anzeigen Weitere Synonyme anzeigen

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Am meisten referenzierte anti-Oxidative-Stress Responsive 1 Antikörper

Human Monoclonal OXSR1 Primary Antibody für ELISA, WB - ABIN564274 : Chiga, Rafiqi, Alessi, Sohara, Ohta, Rai, Sasaki, Uchida: Phenotypes of pseudohypoaldosteronism type II caused by the WNK4 D561A missense mutation are dependent on the WNK-OSR1/SPAK kinase cascade. in Journal of cell science 2011 (PubMed)
Show all 5 Pubmed References
Human Monoclonal OXSR1 Primary Antibody für IF, ELISA - ABIN564266 : Naguro, Umeda, Kobayashi, Maruyama, Hattori, Shimizu, Kataoka, Kim-Mitsuyama, Uchida, Vandewalle, Noguchi, Nishitoh, Matsuzawa, Takeda, Ichijo: ASK3 responds to osmotic stress and regulates blood pressure by suppressing WNK1-SPAK/OSR1 signaling in the kidney. in Nature communications 2012 (PubMed)
Show all 2 Pubmed References
Human Monoclonal OXSR1 Primary Antibody für ELISA, WB - ABIN564275 : Susa, Sohara, Rai, Zeniya, Mori, Mori, Chiga, Nomura, Nishida, Takahashi, Isobe, Inoue, Takeishi, Takeda, Sasaki, Uchida: Impaired degradation of WNK1 and WNK4 kinases causes PHAII in mutant KLHL3 knock-in mice. in Human molecular genetics 2014 (PubMed)
Human Polyclonal OXSR1 Primary Antibody für ICC, IF - ABIN4342122 : Stadler, Hjelmare, Neumann, Jonasson, Pepperkok, Uhlén, Lundberg: Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy. in Journal of proteomics 2012 (PubMed)

Weitere Antikörper gegen Oxidative-Stress Responsive 1 Interaktionspartner

Human Oxidative-Stress Responsive 1 (OXSR1) Interaktionspartner

Data demonstrate that hypotonic low-chloride conditions that activate the WNK1 (zeige WNK1 Antikörper)-SPAK (zeige STK39 Antikörper) and OSR1 pathway promote phosphorylation of NKCC2 (zeige SLC12A1 Antikörper) isoforms.
OSR1 and SPAK (zeige STK39 Antikörper) integrate signals from osmosensing and survival pathways.
our data show a novel role for the WNK1 (zeige WNK1 Antikörper)/OSR1/NKCC1 (zeige SLC12A2 Antikörper) pathway in glioma migration
SPAK (zeige STK39 Antikörper) and OSR1 are powerful negative regulators of the cell volume regulatory Cl- channel ClC-2 (zeige CLCN2 Antikörper)
study identifies a separation of functions for the WNK1 (zeige WNK1 Antikörper)-activated protein kinases OSR1 and SPAK (zeige STK39 Antikörper) in mediating proliferation, invasion, and gene expression in endothelial cells
The CCT (zeige FLVCR2 Antikörper) domain directly interacts with the kinase domain to block substrate access and inhibit the domain-swapped homodimerization of the kinase domain of OSR1.
WNK 1 (zeige WNK1 Antikörper), 3, 4, OSR1, and SPAK (zeige STK39 Antikörper) signaling system known to play a role in regulating the phosphorylation status, and hence activity of the CCCs in other tissues, is also present in the rat and human lenses.
OSR1 has the capacity to downregulate the peptide transporters PEPT1 (zeige SLC15A1 Antikörper) and PEPT2 (zeige SLC15A2 Antikörper) by decreasing the carrier protein abundance in the cell membrane
Both, SPAK (zeige STK39 Antikörper) and OSR1, are negative regulators of the creatine transporter SLC6A8 (zeige SLC6A8 Antikörper)
SPAK (zeige STK39 Antikörper) and OSR1 are negative regulators of EAAT3 (zeige SLC1A1 Antikörper) activity

Mouse (Murine) Oxidative-Stress Responsive 1 (OXSR1) Interaktionspartner

increased phosphorylation of Na(+)-K(+)-2Cl(-) cotransporter in obesity and identifies a new role for AMP-activated protein kinase in regulating the activity of oxidative stress responsive 1 kinase-related proline-alanine-rich protein kinase
OSR1 (zeige OSR1 Antikörper) is expressed in intestine and partial WNK insensitivity of OSR1 (zeige OSR1 Antikörper) increases intestinal Na( )/H( ) exchanger activity and colonic epithelium Na( ) channel activity
Data indicate that SPAK (zeige STK39 Antikörper) and OSR1 (zeige OSR1 Antikörper) function interdependently in the distal convoluted tubule (DCT (zeige DCT Antikörper)) to positively regulate thiazide-sensitive sodium-chloride cotransporter (zeige SLC12A3 Antikörper), NCC (zeige SLC12A3 Antikörper).
Partial OSR1 (zeige OSR1 Antikörper) deficiency influences Na(+)/H(+) exchanger activity, ROS (zeige ROS1 Antikörper) formation, and migration of dendritic cells.
Results clearly establish that PHAII caused by the WNK4 (zeige WNK4 Antikörper) D561A mutation is dependent on the activation of the WNK-OSR1 (zeige OSR1 Antikörper)/SPAK (zeige STK39 Antikörper)-NCC (zeige SLC12A3 Antikörper) cascade.
Two Ste20-like (zeige STK25 Antikörper) kinases that bind and phosphorylate NKCC1 (zeige SLC12A2 Antikörper): Ste20 (zeige STK24 Antikörper)-related proline-alanine-rich kinase (SPAK (zeige STK39 Antikörper)) and oxidative-stress response 1 (OSR1 (zeige OSR1 Antikörper)), were identified.
In the kidneys, NKCC2 (zeige SLC12A1 Antikörper) but not NCC (zeige SLC12A3 Antikörper) is the main target of OSR1 (zeige OSR1 Antikörper) and the reduced p-NKCC2 (zeige SLC12A1 Antikörper) in KSP-OSR1 (zeige OSR1 Antikörper)(-/-) mice may lead to a Bartter-like syndrome.
phosphorylation states of NCC (zeige SLC12A3 Antikörper) and OSR1 (zeige OSR1 Antikörper)/SPAK (zeige STK39 Antikörper) (Gene: Oxsr1, GeneID: 108737) were increased by low-salt diets and decreased by high-salt diets
OSR1 (zeige OSR1 Antikörper), a kinase closely related to SPAK (zeige STK39 Antikörper), exhibited similar kinase properties and similar functional activation of NKCC1 (zeige SLC12A2 Antikörper) when coexpressed with WNK4 (zeige WNK4 Antikörper).
review: NCC (zeige SLC12A3 Antikörper) in the distal convoluted tubule plays a critical role in NaCl and, indirectly, in K+ homeostasis; regulation by SPAK (zeige STK39 Antikörper)/OSR1 (zeige OSR1 Antikörper) kinases and WNKs.

Pig (Porcine) Oxidative-Stress Responsive 1 (OXSR1) Interaktionspartner

The gene shows 92.8% nucleotide identity and 95.5% amino acid identity with human OSR1 (zeige OSR1 Antikörper).

Oxidative-Stress Responsive 1 (OXSR1) Antigen-Profil

Beschreibung des Gens

The product of this gene belongs to the Ser/Thr protein kinase family of proteins. It regulates downstream kinases in response to environmental stress, and may play a role in regulating the actin cytoskeleton.

Alternative names and synonyms associated with Oxidative-Stress Responsive 1 (OXSR1)

oxidative stress responsive 1 (OXSR1) Antikörper
oxidative stress responsive serine rich 1 (OSER1) Antikörper
oxidative stress responsive 1b (oxsr1b) Antikörper
serine/threonine-protein kinase OSR1 (CpipJ_CPIJ015177) Antikörper
serine/threonine-protein kinase OSR1 (Tsp_00299) Antikörper
oxidative-stress responsive 1 (Oxsr1) Antikörper
oxidative stress responsive 1 (Oxsr1) Antikörper
oxidative-stress responsive 1 (oxsr1) Antikörper

2210022N24Rik Antikörper
2810422B09Rik Antikörper
AI462649 Antikörper
AW209236 Antikörper
C20orf111 Antikörper
dJ1183I21.1 Antikörper
HSPC207 Antikörper
mKIAA1101 Antikörper
odd1 Antikörper
osr1 Antikörper
Perit1 Antikörper
zgc:55494 Antikörper
zgc:77321 Antikörper

Bezeichner auf Proteinebene für OXSR1

oxidative stress-responsive 1 protein , oxidative-stress responsive 1 , serine/threonine-protein kinase OSR1 , oxidative stress-responsive 1 , oxidative stress-responsive protein 1 , oxidative stress-responsive serine-rich protein 1 , peroxide-inducible transcript 1 protein

GENE ID	SPEZIES
9943	Homo sapiens
51526	Homo sapiens
394150	Danio rerio
6048779	Culex quinquefasciatus
10901611	Trichinella spiralis
100174028	Pongo abelii
108737	Mus musculus
316064	Rattus norvegicus
607809	Canis lupus familiaris
100050017	Equus caballus
397618	Sus scrofa
100722234	Cavia porcellus
446771	Xenopus laevis

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