OXSR1 Antikörper (AA 351-450)

Produktnummer ABIN564274

Dieser Maus Monoklonal Antikörper detektiert spezifisch OXSR1 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human. Es wurde in 5+ Publikationen zitiert.

Kurzübersicht für OXSR1 Antikörper (AA 351-450) (ABIN564274)

Target: OXSR1 (Oxidative-Stress Responsive 1 (OXSR1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser OXSR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: 5D5

Produktdetails anti-OXSR1 Antikörper

Bindungsspezifität: AA 351-450

Verwendungszweck: Mouse monoclonal antibody raised against a partial recombinant OXSR1.

Sequenz: KAAISQLRSP RVKESISNSE LFPTTDPVGT LLQVPEQISA HLPQPAGQIA TQPTQVSLPP TAEPAKTAQA LSSGSGSQET KIPISLVLRL RNSKKELNDI

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: OXSR1 (AAH08726.1, 351 a.a. ~ 450 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotyp: IgG3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-OXSR1 Antikörper (ABIN564274)

Wakabayashi, Mori, Isobe, Sohara, Susa, Araki, Chiga, Kikuchi, Nomura, Mori, Matsuo, Murata, Nomura, Asano, Kawaguchi, Nonoyama, Rai, Sasaki, Uchida: "Impaired KLHL3-mediated ubiquitination of WNK4 causes human hypertension." in: Cell reports, Vol. 3, Issue 3, pp. 858-68, (2013) (PubMed).

Trudu, Janas, Lanzani, Debaix, Schaeffer, Ikehata, Citterio, Demaretz, Trevisani, Ristagno, Glaudemans, Laghmani, DellAntonio, Loffing, Rastaldi, Manunta, Devuyst, Rampoldi: "Common noncoding UMOD gene variants induce salt-sensitive hypertension and kidney damage by increasing uromodulin expression." in: Nature medicine, Vol. 19, Issue 12, pp. 1655-60, (2013) (PubMed).

Susa, Kita, Iwamoto, Yang, Lin, Ohta, Sohara, Rai, Sasaki, Alessi, Uchida: "Effect of heterozygous deletion of WNK1 on the WNK-OSR1/ SPAK-NCC/NKCC1/NKCC2 signal cascade in the kidney and blood vessels." in: Clinical and experimental nephrology, Vol. 16, Issue 4, pp. 530-8, (2012) (PubMed).

Susa, Sohara, Isobe, Chiga, Rai, Sasaki, Uchida: "WNK-OSR1/SPAK-NCC signal cascade has circadian rhythm dependent on aldosterone." in: Biochemical and biophysical research communications, Vol. 427, Issue 4, pp. 743-7, (2012) (PubMed).

Chiga, Rafiqi, Alessi, Sohara, Ohta, Rai, Sasaki, Uchida: "Phenotypes of pseudohypoaldosteronism type II caused by the WNK4 D561A missense mutation are dependent on the WNK-OSR1/SPAK kinase cascade." in: Journal of cell science, Vol. 124, Issue Pt 9, pp. 1391-5, (2011) (PubMed).

Details zu OXSR1

Target: OXSR1 (Oxidative-Stress Responsive 1 (OXSR1))

Andere Bezeichnung: OXSR1

Hintergrund: Full Gene Name: oxidative-stress responsive 1
Synonyms: KIAA1101,OSR1

Gen-ID: 9943

Pathways: Tube Formation