Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Alle Spezies anzeigen
Weitere Synonyme anzeigen
Wählen Sie die Spezies und Applikation aus
anti-Human HLA-DRB1 Antikörper:
anti-Monkey HLA-DRB1 Antikörper:
anti-Baboon HLA-DRB1 Antikörper:
Sie gelangen zu unserer vorgefilterten Suche.
Human Polyclonal HLA-DRB1 Primary Antibody für WB - ABIN1944757
Tonnelle, DeMars, Long: DO beta: a new beta chain gene in HLA-D with a distinct regulation of expression. in The EMBO journal 1986
Show all 5 Pubmed References
Human Polyclonal HLA-DRB1 Primary Antibody für WB - ABIN516510
Cao, Schmitz, Yang, Hogan, Bunch, Hu, Jennette, Berg, Arnett, Jennette, Falk, Preston: DRB1*15 allele is a risk factor for PR3-ANCA disease in African Americans. in Journal of the American Society of Nephrology : JASN 2011
Using genome-wide association meta-analysis authors discover two regions associated with longevity (HLA-DQA1/DRB1 and LPA).
The risk of actinic prurigo associated with HLA-DRB1*03:01 in Chinese patients living in Singapore is reported.
These results have shown a strong association of HLA-DRB1*03 with MG, especially for EOMG also in our population. HLA-DRB1*01 was associated to LOMG suggesting that is a susceptibility factor for this subgroup of the disease.
The difference in MS risk between the extremes was considerable; smokers carrying HLA-DRB1*15 and lacking HLA-A*02 had a 13-fold increased risk compared with never smokers without these genetic risk factors (OR 12.7, 95% CI 10.8-14.9). The risk of MS associated with HLA genotypes is strongly influenced by smoking status and vice versa.
HLA-DRB1/DQB1 gene variants appeared to modulate the alteration of the left posterior cingulate volume, hence modulating the susceptibility of Alzheimer's disease.
There are hundreds of polymorphisms of HLA-DRB1 which have been associated with different autoimmune disorders as well as with immune response to infection and vaccines. It is possible that the interaction of specific HLA with pathogenic antigens is one of the keys favoring (or protecting) toward the development of an autoimmune disease.[Review]
Suggest an independent leading contribution of rs17879599 in the 2nd exon of HLA-DRB1 gene to hepatocellular carcinoma risk in Han Chinese.
None of the 13 individuals with the rs7903146 TT genotype carried the highest Type 1 diabetes risk HLA genotype, i.e. DRB1 (zeige RBM45 Antikörper)*03:01/DR4 (zeige HLADRB4 Antikörper) (DRB1 (zeige RBM45 Antikörper)*0401, *04:05 or *04:02), compared with 29.4% (27/92) of those without it (P=0.023). The DRB1 (zeige RBM45 Antikörper)*03:01 allele was present in 15.4% (2/13) of individuals with the single nucleotide polymorphism, compared with 59.8% (55/92) of those without it (P=0.003).
the 'GG/G' of CTLA4 (zeige CTLA4 Antikörper) +49AG SNP, HLA-DRB1*11/-DRB1 (zeige RBM45 Antikörper)*12 (DR5 (zeige TNFRSF10B Antikörper)) alleles and the combinations of DRB1 (zeige RBM45 Antikörper)*11/DRB1 (zeige RBM45 Antikörper)*12 alleles with AG/GG genotype and DRB1 (zeige RBM45 Antikörper)*04/07/12 alleles with GG genotype may act as synergistic manner to confer the strong susceptibility to autoimmune thyroid diseases in south India
A total of 39 HLA-A, 66 HLA-B and 47 HLA-DRB1 alleles were identified.
HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa. It is encoded by 6 exons. Exon one encodes the leader peptide\; exons 2 and 3 encode the two extracellular domains\; exon 4 encodes the transmembrane domain\; and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogs DRB3, DRB4 and DRB5. DRB1 is present in all individuals. Allelic variants of DRB1 are linked with either none or one of the genes DRB3, DRB4 and DRB5. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9.
major histocompatibility complex, class II, DR beta 1
, HLA class II histocompatibility antigen, DR-1 beta chain
, MHC class II HLA-DR beta 1 chain
, MHC class II HLA-DR-beta cell surface glycoprotein
, MHC class II HLA-DRw10-beta
, MHC class II antigen
, human leucocyte antigen DRB1
, lymphocyte antigen DRB1