anti-EOMES (EOMES) Antikörper

Human Eomesodermin (EOMES) Interaktionspartner

1. EOMES specifically activates a cardiogenic program in human embryonic stem cells.

2. Studies suggest there are two nonoverlapping NK cell populations that are potentially liver resident in humans: CD49a (zeige ITGA1 Antikörper)+ NK cells and Eomes hi.

3. Reciprocal regulation of BMF (zeige BMF Antikörper) and BIRC5 (zeige BIRC5 Antikörper) is linked to Eomes overexpression in colorectal cancer.

4. Eomes(hi) NK cells can be recruited from the circulation during adult life and that circulating Eomes(lo) NK cells are able to upregulate Eomes and molecules mediating liver retention under cytokine conditions similar to those in the liver.

5. EOMES expression was low in multiple sclerosis (MS), and stable over time. The low EOMES/TBX21 phenotype in MS reflects cd56 (zeige NCAM1 Antikörper)+ cell dysregulation.

6. we identified a higher Eomes mRNA expression as an independent good prognostic factor for OS and PFS in mRCC patients treated with sorafenib.

7. Eomes(+) CD4(+) T cells are increased in the peripheral blood and cerebrospinal fluid from patients in a progressive state of multiple sclerosis.

8. the level of T-bet and Eomesodermin, two T-box transcription factors regulating lymphocyte effector functions, is strongly reduced in NK cells from allogeneic hematopoietic stem cell transplantation recipients compared with healthy control subjects.

9. This study showed that EOMES (rs2724509; flanking) associated with Alzheimer disease.

10. This study supports the concept that poor human viral-specific CD8 (zeige CD8A Antikörper)(+) T cell functionality is due to an inverse expression balance between T-bet and Eomes

Zebrafish Eomesodermin (EOMES) Interaktionspartner

1. Smad2 (zeige SMAD2 Antikörper) and Eomesodermin a (Eomesa) bind common genomic regions proximal to genes involved in mesoderm and endoderm formation, suggesting Eomesa forms a general component of the Smad2 (zeige SMAD2 Antikörper) signalling complex in zebrafish.

2. Eomesa has a strictly maternal role in the initiation of epiboly, and is required for normal expression of the endoderm markers sox32, bon and og9x; however it is not essential for endoderm formation.

3. Eomes is a Nodal-transducing factor that acts, directly and indirectly, in concert with FoxH1 (zeige FOXH1 Antikörper) to carry out all Nodal-dependent processes during early mesendoderm specification.

4. Eomes plays a role in specifying the embryonic organizer.

5. regulates the expression of a zygotic homeobox (zeige PRRX1 Antikörper) transcription factor mtx2 (zeige MTX2 Antikörper)

6. Results suggest that eomesodermin promotes endoderm induction in marginal blastomeres by facilitating the assembly of a transcriptional activating complex on the casanova promoter.

7. These results suggest that both Eomes genes are involved in the zebrafish immune response, particularly in lymphocyte function as has been found in mammals.

Cow (Bovine) Eomesodermin (EOMES) Interaktionspartner

1. as conceptuses attach to the uterine epithelium, IFNT gene transcription is down-regulated by an increase in EOMES expression and EOMES-CREBBP (zeige CREBBP Antikörper) binding in the attached trophoblast cells.

Mouse (Murine) Eomesodermin (EOMES) Interaktionspartner

1. These data indicate that TBR2 contributes to suppressing RA signaling in INPs, thereby enabling them to re-enter the cell cycle and delay neuronal differentiation.

2. These data identify TBR2 as a major determinant of the INP-specific traits by regulating both genetic and epigenetic pathways.

3. Tbr2 regulates the tempo of laminar fate implementation for all cortical layers.

4. results revealed Eomes expression is restricted to distinct tissues and Vgamma subsets; gammadelta T cells expressing Eomes presented a CD44 (zeige CD44 Antikörper)+-activated memory phenotype with increased expression of Ly6C and Il2rb (zeige IL2RB Antikörper) and showed higher IFN-gamma (zeige IFNG Antikörper) production upon stimulation; Eomes expression could be induced in peripheral and thymic gammadelta T cells by IL-12 (zeige IL12A Antikörper) and in particular by IL-4 (zeige IL4 Antikörper)

5. activation of the Eomes target genes Foxa2 (zeige FOXA2 Antikörper) and Lhx1 (zeige LHX1 Antikörper) is associated with higher order chromatin reorganization.

6. this study shows that TGF-beta (zeige TGFB1 Antikörper) promotes salivary gland innate lymphoid cells differentiation by suppressing Eomes

7. The Foxo3 (zeige FOXO3 Antikörper)-Eomes pathway is central to achieve the complete specialized gene program required for pathogenic Th1 (zeige HAND1 Antikörper) cell differentiation.

8. HDAC11-knockout T cells displayed enhanced proliferation, proinflammatory cytokine production, and effector molecule expression of Eomes and TBX21 transcription factors previously shown to regulate inflammatory cytokine and effector molecule production.

9. increases the number of ALP (zeige CCL21A Antikörper)-positive colonies after iPSC induction and decreases expression levels of Eomes and p21 (zeige D4S234E Antikörper) mRNAs. Based on these observations, we propose that the CCR4 (zeige CCR4 Antikörper)-NOT deadenylase activity contributes to iPSC induction.

10. Results indicated that Eomes bound to the Ifng (zeige IFNG Antikörper) promoter and multiple conserved noncoding sequences in stimulation-dependent and stimulation-independent manners.

Pig (Porcine) Eomesodermin (EOMES) Interaktionspartner

1. the expression of T-bet, Eomes and GATA-3 (zeige GATA3 Antikörper) in combination with additional differentiation molecules within CD4 (zeige CD4 Antikörper)+ and CD8beta+ T cell subsets from different organs of healthy pigs.