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STIM1 Antikörper

(Stromal Interaction Molecule 1 (STIM1))
This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6 kb from the 5' end of the RRM1 gene.[provided by RefSeq, Jan 2009].

Häufig verwendete STIM1 Antikörper

Aktuelle Publikationen für unsere STIM1 Antikörper

Zhou, Gu, Li, Li, Zhu, Gao, Zang, Wang, Shan, Yang: "Suppression of STIM1 inhibits the migration and invasion of human prostate cancer cells and is associated with PI3K/Akt signaling inactivation." in: Oncology reports, Vol. 38, Issue 5, pp. 2629-2636, (2018) (PubMed).

Wu, Hsu, Wang, Liang, Tsai, Yen, Li, Chiu, Chang, Huang, Lin, Yoshioka: "A Novel Strategy for TNF-Alpha Production by 2-APB Induced Downregulated SOCE and Upregulated HSP70 in O. tsutsugamushi-Infected Human Macrophages." in: PLoS ONE, Vol. 11, Issue 7, pp. e0159299, (2017) (PubMed).

Chen, Zhang, Wu, Shi, Yan, Mei, Tolleson, Guo: "Endoplasmic Reticulum Stress and Store-Operated Calcium Entry Contribute to Usnic Acid-Induced Toxicity in Hepatic Cells." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 146, Issue 1, pp. 116-26, (2015) (PubMed).

Hong, Chang, Wang, Yu, Lee: "IL-9 induces IL-8 production via STIM1 activation and ERK phosphorylation in epidermal keratinocytes: A plausible mechanism of IL-9R in atopic dermatitis." in: Journal of dermatological science, Vol. 78, Issue 3, pp. 206-14, (2015) (PubMed).

Wang, Choi, Richardson, Reid, Seymen, Yildirim, Tuna, Gençay, Simmer, Hu: "STIM1 and SLC24A4 Are Critical for Enamel Maturation." in: Journal of dental research, Vol. 93, Issue 7 Suppl, pp. 94S-100S, (2015) (PubMed).

Ambily, Kaiser, Pierro, Chamberlain, Li, Jones, Kassouf, Gibbins, Authi: "The role of plasma membrane STIM1 and Ca(2+)entry in platelet aggregation. STIM1 binds to novel proteins in human platelets." in: Cellular signalling, Vol. 26, Issue 3, pp. 502-11, (2014) (PubMed).

Umemura, Baljinnyam, Feske, De Lorenzo, Xie, Feng, Oda, Makino, Fujita, Yokoyama, Iwatsubo, Chen, Goydos, Ishikawa, Iwatsubo: "Store-operated Ca2+ entry (SOCE) regulates melanoma proliferation and cell migration." in: PLoS ONE, Vol. 9, Issue 2, pp. e89292, (2014) (PubMed).

Ferdaus, Xiao, Ohara, Nemoto, Harada, Saar, Hübner, Isomura, Nabika: "Identification of Stim1 as a candidate gene for exaggerated sympathetic response to stress in the stroke-prone spontaneously hypertensive rat." in: PLoS ONE, Vol. 9, Issue 4, pp. e95091, (2014) (PubMed).

Misceo, Holmgren, Louch, Holme, Mizobuchi, Morales, De Paula, Stray-Pedersen, Lyle, Dalhus, Christensen, Stormorken, Tjønnfjord, Frengen: "A dominant STIM1 mutation causes Stormorken syndrome." in: Human mutation, Vol. 35, Issue 5, pp. 556-64, (2014) (PubMed).

Shen, Zhu, Zhang, Jiang, Wang, Zhang, Li, Huang, Ke, Ma, Du: "Attenuated mesangial cell proliferation related to store-operated Ca(2+) entry in aged rat: the role of STIM 1 and Orai 1." in: Age (Dordrecht, Netherlands), Vol. 35, Issue 6, pp. 2193-202, (2013) (PubMed).

Aliase für STIM1 Antikörper

stromal interaction molecule 1 (STIM1) Antikörper
stromal interaction molecule 1 (stim1) Antikörper
stromal interaction molecule 1a (stim1a) Antikörper
stromal interaction molecule 1 L homeolog (stim1.L) Antikörper
stromal interaction molecule 1b (stim1b) Antikörper
stromal interaction molecule 1 (Stim1) Antikörper
D11S4896E Antikörper
GOK Antikörper
MGC76045 Antikörper
MGC154748 Antikörper
si:ch211-112l17.2 Antikörper
si:dkey-24p1.5 Antikörper
SIM Antikörper
stim1 Antikörper
STIM1 Antikörper
Stim1 Antikörper
TAM Antikörper
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