SPAM1 Produkte
(Sperm Adhesion Molecule 1 (PH-20 Hyaluronidase, Zona Pellucida Binding) (SPAM1))
Kategorien
Hyaluronidase degrades hyaluronic acid, a major structural proteoglycan found in extracellular matrices and basement membranes. Six members of the hyaluronidase family are clustered into two tightly linked groups on chromosome 3p21.3 and 7q31.3. This gene was previously referred to as HYAL1 and HYA1 and has since been assigned the official symbol SPAM1\; another family member on chromosome 3p21.3 has been assigned HYAL1. This gene encodes a GPI-anchored enzyme located on the human sperm surface and inner acrosomal membrane. This multifunctional protein is a hyaluronidase that enables sperm to penetrate through the hyaluronic acid-rich cumulus cell layer surrounding the oocyte, a receptor that plays a role in hyaluronic acid induced cell signaling, and a receptor that is involved in sperm-zona pellucida adhesion. Abnormal expression of this gene in tumors has implicated this protein in degradation of basement membranes leading to tumor invasion and metastasis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010].
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Ausgewählte SPAM1 Kategorien
SPAM1 Antikörper
High quality antibodies with extensive validation data.
SPAM1 ELISA Kits
Reliable ELISA kits for a wide range of species.
SPAM1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene SPAM1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC
Validierungen
- (3)
Kat. Nr.
ABIN6265252
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (6)
- (1)
Kat. Nr.
ABIN562973
Menge
50 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (1)
Kat. Nr.
ABIN1537320
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene SPAM1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6974834
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6959661
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6959662
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene SPAM1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1321072
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN6964321
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Rat
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7422412
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren SPAM1 Produkten
: "Hyaluronan synthases and hyaluronidases in nasal polyps." in: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, Vol. 273, Issue 7, pp. 1801-8, (2016) (PubMed).: "Expression of a functional recombinant oleosin-human hyaluronidase hPH-20 fusion in Arabidopsis thaliana." in: Protein expression and purification, Vol. 103, pp. 23-7, (2014) (PubMed).
: "Investigation of the mechanisms by which the molecular chaperone HSPA2 regulates the expression of sperm surface receptors involved in human sperm-oocyte recognition." in: Molecular human reproduction, Vol. 19, Issue 3, pp. 120-35, (2013) (PubMed).
: "Autodisplay of catalytically active human hyaluronidase hPH-20 and testing of enzyme inhibitors." in: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, Vol. 42, Issue 1-2, pp. 138-47, (2010) (PubMed).
: "Hyaluronidase expression and activity is regulated by pro-inflammatory cytokines in human airway epithelial cells." in: American journal of respiratory cell and molecular biology, Vol. 39, Issue 3, pp. 289-95, (2008) (PubMed).
in: (PubMed).
Synonyme und alternative Namen zu SPAM1
sperm adhesion molecule 1 (Spam1), sperm adhesion molecule 1 (SPAM1), sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) L homeolog (spam1.L), sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) (SPAM1), sperm adhesion molecule 1 (spam1), AV039194, HYA1, HYAL1, HYAL3, HYAL5, im:6902904, Ph-20, PH-20, PH20, SPAG15, Spam, spam1, XEH1, zgc:158668Bezeichner auf Proteinebene für SPAM1
- hyal-PH20
- hyaluronidase PH-20
- hyaluronoglucosaminidase PH-20
- sperm surface protein PH-20
- sperm protein PH-20
- PH-20 protein
- sperm surface antigen 2B1
- hyaluronidase
- sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) L homeolog
- hyaluronidase, zona pellucida binding
- sperm adhesion molecule 1
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