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SPANXB1 Produkte

(SPANX Family, Member B1 (SPANXB1))

Kategorien

Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene maps to chromosome X in a head-to-tail orientation with SPANX family member B2, which appears to be a duplication of the B1 locus. The SPANXB genes are unique members of this gene family, since they contain an additional 18 nt in their coding region compared to the majority of family members. Although the protein encoded by this gene contains consensus nuclear localization signals, the major site for subcellular localization of expressed protein is in the cytoplasmic droplets of ejaculated spermatozoa. This protein provides a biochemical marker for studying the unique structures in spermatazoa, while attempting to further define its role in spermatogenesis. [provided by RefSeq, Jul 2008].

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Ausgewählte SPANXB1 Kategorien

SPANXB1 Antikörper

High quality antibodies with extensive validation data.

Empfohlene SPANXB1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (4)
  • (1)
Kat. Nr. ABIN1881824
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (2)
Kat. Nr. ABIN531836
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (1)
Kat. Nr. ABIN531837
Menge 200 μL
Datenblatt Datenblatt

Empfohlene SPANXB1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6234137
Menge 96 tests
Datenblatt Datenblatt

Empfohlene SPANXB1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1321076
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3077380
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SPANXB1 Produkten

Hansen, Eichler, Fullerton, Carrell: "SPANX gene variation in fertile and infertile males." in: Systems biology in reproductive medicine, Vol. 55, pp. 18-26, (2010) (PubMed).

Hansen, Nielsen, Retelska, Larsen, Leffers: "A shared promoter region suggests a common ancestor for the human VCX/Y, SPANX, and CSAG gene families and the murine CYPT family." in: Molecular reproduction and development, Vol. 75, Issue 2, pp. 219-29, (2007) (PubMed).

Kouprina, Pavlicek, Noskov, Solomon, Otstot, Isaacs, Carpten, Trent, Schleutker, Barrett, Jurka, Larionov: "Dynamic structure of the SPANX gene cluster mapped to the prostate cancer susceptibility locus HPCX at Xq27." in: Genome research, Vol. 15, Issue 11, pp. 1477-86, (2005) (PubMed).

Zendman, Zschocke, van Kraats, de Wit, Kurpisz, Weidle, Ruiter, Weiss, van Muijen: "The human SPANX multigene family: genomic organization, alignment and expression in male germ cells and tumor cell lines." in: Gene, Vol. 309, Issue 2, pp. 125-33, (2003) (PubMed).

Synonyme und alternative Namen zu SPANXB1

SPANX family member B1 (SPANXB1), B1, CT11.2, SPANX-B, SPANXB

Bezeichner auf Proteinebene für SPANXB1

  • SPANX family member B/F
  • cancer/testis antigen 11.2
  • cancer/testis antigen family 11, member 2
  • nuclear-associated protein SPAN-Xb
  • nuclear-associated protein SPAN-Xf
  • sperm protein associated with the nucleus on the X chromosome B/F
  • sperm protein associated with the nucleus, X chromosome, family member B1
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