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SPANXC Produkte

(SPANX Family, Member C (SPANXC))

Kategorien

Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family, which is located in a gene cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a protein that localizes to the nucleus and is expressed in highly metastatic cell lines, making the protein a potential diagnostic and prognostic marker. The protein belongs to a family of cancer/testis antigens and represents a potential target for cancer immunotherapy. [provided by RefSeq, Jul 2008].

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Ausgewählte SPANXC Kategorien

SPANXC Antikörper

High quality antibodies with extensive validation data.

Empfohlene SPANXC Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ELISA, WB, IHC (p), IF (p), IF (cc), IHC (fro)
Validierungen
  • (2)
Kat. Nr. ABIN721675
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IHC
Validierungen
  • (1)
Kat. Nr. ABIN7170464
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, WB
Validierungen
  • (1)
Kat. Nr. ABIN129672
Menge 100 μg
Datenblatt Datenblatt

Empfohlene SPANXC ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6207624
Menge 96 tests
Datenblatt Datenblatt

Empfohlene SPANXC Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN3077438
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SPANXC Produkten

Kouprina, Pavlicek, Noskov, Solomon, Otstot, Isaacs, Carpten, Trent, Schleutker, Barrett, Jurka, Larionov: "Dynamic structure of the SPANX gene cluster mapped to the prostate cancer susceptibility locus HPCX at Xq27." in: Genome research, Vol. 15, Issue 11, pp. 1477-86, (2005) (PubMed).

Westbrook, Schoppee, Diekman, Klotz, Allietta, Hogan, Slingluff, Patterson, Frierson, Irvin, Flickinger, Coppola, Herr: "Genomic organization, incidence, and localization of the SPAN-x family of cancer-testis antigens in melanoma tumors and cell lines." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 10, Issue 1 Pt 1, pp. 101-12, (2004) (PubMed).

Kouprina, Mullokandov, Rogozin, Collins, Solomon, Otstot, Risinger, Koonin, Barrett, Larionov: "The SPANX gene family of cancer/testis-specific antigens: rapid evolution and amplification in African great apes and hominids." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 9, pp. 3077-82, (2004) (PubMed).

Zendman, Zschocke, van Kraats, de Wit, Kurpisz, Weidle, Ruiter, Weiss, van Muijen: "The human SPANX multigene family: genomic organization, alignment and expression in male germ cells and tumor cell lines." in: Gene, Vol. 309, Issue 2, pp. 125-33, (2003) (PubMed).

Synonyme und alternative Namen zu SPANXC

SPANX family member C (SPANXC), C, CT11.3, CTp11, SPANX-C

Bezeichner auf Proteinebene für SPANXC

  • SPAN-Xc protein
  • cancer-testis-associated protein CTp11
  • cancer/testis antigen 11.3
  • cancer/testis antigen family 11, member 3
  • cancer/testis-associated protein CTp11
  • cancer/testis-associated protein of 11 kD
  • nuclear-associated protein SPAN-Xc
  • sperm protein associated with the nucleus on the X chromosome C
  • sperm protein associated with the nucleus, X chromosome, family member C
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