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SOS1 Produkte

(Son of Sevenless Homolog 1 (SOS1))

Kategorien

This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq, Jul 2008].

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Ausgewählte SOS1 Kategorien

SOS1 Antikörper

High quality antibodies with extensive validation data.

SOS1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SOS1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF, IHC
Validierungen
  • (4)
Kat. Nr. ABIN7170318
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, PLA
Validierungen
  • (4)
Kat. Nr. ABIN520376
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, IF, ICC
Validierungen
  • (3)
  • (2)
Kat. Nr. ABIN535287
Menge 100 μg
Datenblatt Datenblatt

Empfohlene SOS1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6970366
Menge 96 tests
Datenblatt Datenblatt

Empfohlene SOS1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1320973
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3095504
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3135535
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SOS1 Produkten

Harris, Parry, Westwick, Ward: "Phosphoinositide lipid phosphatases: natural regulators of phosphoinositide 3-kinase signaling in T lymphocytes." in: The Journal of biological chemistry, Vol. 283, Issue 5, pp. 2465-9, (2008) (PubMed).

Bernards, Settleman: "GEFs in growth factor signaling." in: Growth factors (Chur, Switzerland), Vol. 25, Issue 5, pp. 355-61, (2008) (PubMed).

McDonald, Seldeen, Deegan, Farooq: "Structural basis of the differential binding of the SH3 domains of Grb2 adaptor to the guanine nucleotide exchange factor Sos1." in: Archives of biochemistry and biophysics, Vol. 479, Issue 1, pp. 52-62, (2008) (PubMed).

Xing, Hamaguchi: "Effects of SHIP-1 on MMP2 secretion and invasion of SR3Y1 cells." in: Journal of genetics and genomics = Yi chuan xue bao, Vol. 34, Issue 4, pp. 285-93, (2007) (PubMed).

Tarasenko, Kole, Chi, Mentink-Kane, Wynn, Bolland: "T cell-specific deletion of the inositol phosphatase SHIP reveals its role in regulating Th1/Th2 and cytotoxic responses." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 27, pp. 11382-7, (2007) (PubMed).

Furuta, Miura, Copeland, Shang, Oshima, Kamata: "Light Chain 3 associates with a Sos1 guanine nucleotide exchange factor: its significance in the Sos1-mediated Rac1 signaling leading to membrane ruffling." in: Oncogene, Vol. 21, Issue 46, pp. 7060-6, (2002) (PubMed).

Kardinal, Konkol, Lin, Eulitz, Schmidt, Estrov, Talpaz, Arlinghaus, Feller: "Chronic myelogenous leukemia blast cell proliferation is inhibited by peptides that disrupt Grb2-SoS complexes." in: Blood, Vol. 98, Issue 6, pp. 1773-81, (2001) (PubMed).

Salojin, Zhang, Meagher, Delovitch: "ZAP-70 is essential for the T cell antigen receptor-induced plasma membrane targeting of SOS and Vav in T cells." in: The Journal of biological chemistry, Vol. 275, Issue 8, pp. 5966-75, (2000) (PubMed).

Scita, Tenca, Frittoli, Tocchetti, Innocenti, Giardina, Di Fiore: "Signaling from Ras to Rac and beyond: not just a matter of GEFs." in: The EMBO journal, Vol. 19, Issue 11, pp. 2393-8, (2000) (PubMed).

Buday, Downward: "Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor." in: Cell, Vol. 73, Issue 3, pp. 611-20, (1993) (PubMed).

Synonyme und alternative Namen zu SOS1

SOS Ras/Rac guanine nucleotide exchange factor 1 (SOS1), son of sevenless homolog 1 (Drosophila) (Sos1), SOS Ras/Rac guanine nucleotide exchange factor 1 (Sos1), 4430401P03Rik, 9630010N06, AI449023, GF1, GGF1, GINGF, HGF, NS4

Bezeichner auf Proteinebene für SOS1

  • SOS-1
  • gingival fibromatosis, hereditary, 1
  • guanine nucleotide exchange factor
  • son of sevenless homolog 1
  • guanine nucleotide releasing factor
  • ras guanine exchange factor
  • son-of-sevenless 1
  • Son of sevenless homolog 1
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