SLC22A12 Produkte
(Solute Carrier Family 22 (Organic Anion/urate Transporter), Member 12 (SLC22A12))
Kategorien
The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013].
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Ausgewählte SLC22A12 Kategorien
SLC22A12 Antikörper
High quality antibodies with extensive validation data.
SLC22A12 ELISA Kits
Reliable ELISA kits for a wide range of species.
SLC22A12 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene SLC22A12 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (2)
- (3)
Kat. Nr.
ABIN530376
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (3)
Kat. Nr.
ABIN7192423
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Rat
Applikation
IHC, IF
Validierungen
- (2)
Kat. Nr.
ABIN7075662
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene SLC22A12 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6959579
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6959580
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN2540220
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene SLC22A12 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7551708
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7559315
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1320195
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren SLC22A12 Produkten
: "Phloretin attenuates hyperuricemia-induced endothelial dysfunction through co-inhibiting inflammation and GLUT9-mediated uric acid uptake." in: Journal of cellular and molecular medicine, Vol. 21, Issue 10, pp. 2553-2562, (2018) (PubMed).: "Coevolution of URAT1 and Uricase during Primate Evolution: Implications for Serum Urate Homeostasis and Gout." in: Molecular biology and evolution, Vol. 33, Issue 9, pp. 2193-200, (2016) (PubMed).
: "OIT3 deficiency impairs uric acid reabsorption in renal tubule." in: FEBS letters, Vol. 586, Issue 6, pp. 760-5, (2012) (PubMed).
: "Sucrose induces fatty liver and pancreatic inflammation in male breeder rats independent of excess energy intake." in: Metabolism: clinical and experimental, Vol. 60, Issue 9, pp. 1259-70, (2011) (PubMed).
: "The SLC22 drug transporter family." in: Pflügers Archiv : European journal of physiology, Vol. 447, Issue 5, pp. 666-76, (2004) (PubMed).
: "[Molecular biology of urate transporter]." in: Seikagaku. The Journal of Japanese Biochemical Society, Vol. 76, Issue 2, pp. 101-10, (2004) (PubMed).
: "The multivalent PDZ domain-containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C terminus." in: The Journal of biological chemistry, Vol. 279, Issue 44, pp. 45942-50, (2004) (PubMed).
: "Two male siblings with hereditary renal hypouricemia and exercise-induced ARF." in: American journal of kidney diseases : the official journal of the National Kidney Foundation, Vol. 42, Issue 6, pp. 1287-92, (2003) (PubMed).
: "Clinical and molecular analysis of patients with renal hypouricemia in Japan-influence of URAT1 gene on urinary urate excretion." in: Journal of the American Society of Nephrology : JASN, Vol. 15, Issue 1, pp. 164-73, (2003) (PubMed).
Synonyme und alternative Namen zu SLC22A12
solute carrier family 22 (organic anion/cation transporter), member 12 (Slc22a12), solute carrier family 22 member 12 (SLC22A12), solute carrier family 22 member 12 (Slc22a12), AI987855, OAT4L, Rst, RST, Slc22al2, URAT1Bezeichner auf Proteinebene für SLC22A12
- renal-specific transporter
- solute carrier family 22 (organic cation transporter)-like 2
- solute carrier family 22 member 12
- urate anion exchanger 1
- organic anion transporter 4-like protein
- solute carrier family 22 (organic anion/cation transporter), member 12
- urate transporter 1
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