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SLC12A6 Produkte

(Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 6 (SLC12A6))

Kategorien

This gene is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy. [provided by RefSeq, Jul 2008].

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Ausgewählte SLC12A6 Kategorien

SLC12A6 Antikörper

High quality antibodies with extensive validation data.

SLC12A6 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SLC12A6 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC (p)
Validierungen
  • (2)
Kat. Nr. ABIN656316
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (4)
  • (1)
Kat. Nr. ABIN564298
Menge 50 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC
Validierungen
  • (2)
Kat. Nr. ABIN238578
Menge 100 μg
Datenblatt Datenblatt

Empfohlene SLC12A6 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1320131
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN3087608
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN3087609
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SLC12A6 Produkten

Shiozaki, Takemoto, Ichikawa, Fujiwara, Konishi, Kosuga, Komatsu, Okamoto, Kishimoto, Marunaka, Otsuji: "The K-Cl cotransporter KCC3 as an independent prognostic factor in human esophageal squamous cell carcinoma." in: BioMed research international, Vol. 2014, pp. 936401, (2014) (PubMed).

Salin-Cantegrel, Shekarabi, Rasheed, Charron, Laganière, Gaudet, Dion, Lapointe, Rouleau: "Potassium-chloride cotransporter 3 interacts with Vav2 to synchronize the cell volume decrease response with cell protrusion dynamics." in: PLoS ONE, Vol. 8, Issue 5, pp. e65294, (2013) (PubMed).

Shekarabi, Moldrich, Rasheed, Salin-Cantegrel, Laganière, Rochefort, Hince, Huot, Gaudet, Kurniawan, Sotocinal, Ritchie, Dion, Mogil, Richards, Rouleau et al.: "Loss of neuronal potassium/chloride cotransporter 3 (KCC3) is responsible for the degenerative phenotype in a conditional mouse model of hereditary motor and sensory neuropathy associated with ..." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 11, pp. 3865-76, (2012) (PubMed).

Salin-Cantegrel, Rivière, Shekarabi, Rasheed, Dacal, Laganière, Gaudet, Rochefort, Lesca, Gaspar, Dion, Lapointe, Rouleau: "Transit defect of potassium-chloride Co-transporter 3 is a major pathogenic mechanism in hereditary motor and sensory neuropathy with agenesis of the corpus callosum." in: The Journal of biological chemistry, Vol. 286, Issue 32, pp. 28456-65, (2011) (PubMed).

Salin-Cantegrel, Shekarabi, Holbert, Dion, Rochefort, Laganière, Dacal, Hince, Karemera, Gaspar, Lapointe, Rouleau: "HMSN/ACC truncation mutations disrupt brain-type creatine kinase-dependant activation of K+/Cl- co-transporter 3." in: Human molecular genetics, Vol. 17, Issue 17, pp. 2703-11, (2008) (PubMed).

Simard, Bergeron, Frenette-Cotton, Carpentier, Pelchat, Caron, Isenring: "Homooligomeric and heterooligomeric associations between K+-Cl- cotransporter isoforms and between K+-Cl- and Na+-K+-Cl- cotransporters." in: The Journal of biological chemistry, Vol. 282, Issue 25, pp. 18083-93, (2007) (PubMed).

Synonyme und alternative Namen zu SLC12A6

solute carrier family 12, member 6 (Slc12a6), solute carrier family 12 member 6 (SLC12A6), 9530023I19Rik, ACCPN, gaxp, Kcc3, KCC3, KCC3A, KCC3B

Bezeichner auf Proteinebene für SLC12A6

  • solute carrier family 12 member 6
  • furosemide-sensitive KCl cotransporter 3
  • K-Cl cotransporter 3
  • electroneutral potassium-chloride cotransporter 3
  • potassium chloride cotransporter 3
  • potassium chloride cotransporter KCC3a-S3
  • potassium-chloride transporter-3a
  • potassium-chloride transporter-3b
  • solute carrier family 12 (potassium/chloride transporters), member 6
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