Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This SLC12A6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human SLC12A6.
Kcc3 antikoerper, ACCPN antikoerper, KCC3 antikoerper, KCC3A antikoerper, KCC3B antikoerper, 9530023I19Rik antikoerper, gaxp antikoerper, solute carrier family 12, member 6 antikoerper, solute carrier family 12 member 6 antikoerper, Slc12a6 antikoerper, SLC12A6 antikoerper
Hintergrund
This gene is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy.