Shugoshin Produkte
(Shugoshin 1 (SGOL1))
Kategorien
Plays a central role in chromosome cohesion during mitosis by preventing premature dissociation of cohesin complex from centromeres after prophase, when most of cohesin complex dissociates from chromosomes arms. May act by preventing phosphorylation of the stag2 subunit of cohesin complex at the centromere, ensuring cohesin persistence at centromere until cohesin cleavage by espl1/separase at anaphase. May regulate kinetochore microtubule stability in mitosis, possibly to sense tension on mitotic chromosomes.
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Ausgewählte Shugoshin Kategorien
Shugoshin Antikörper
High quality antibodies with extensive validation data.
Shugoshin Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Shugoshin Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
ELISA, WB, IP
Validierungen
- (9)
- (4)
Kat. Nr.
ABIN566873
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, WB, IF
Validierungen
- (3)
Kat. Nr.
ABIN7169545
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Schizosaccharomyces pombe
Applikation
WB, IF
Validierungen
- (3)
- (3)
Kat. Nr.
ABIN2452123
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Shugoshin ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN5648311
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6233627
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Shugoshin Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7564961
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7555476
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN2731936
Menge
20 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Shugoshin Produkten
: "Negative feedback at kinetochores underlies a responsive spindle checkpoint signal." in: Nature cell biology, Vol. 16, Issue 12, pp. 1257-64, (2014) (PubMed).: "B56? tumor-associated mutations provide new mechanisms for B56?-PP2A tumor suppressor activity." in: Molecular cancer research : MCR, Vol. 11, Issue 9, pp. 995-1003, (2013) (PubMed).
: "Centromere DNA decatenation depends on cohesin removal and is required for mammalian cell division." in: Journal of cell science, Vol. 123, Issue Pt 5, pp. 806-13, (2010) (PubMed).
: "A B56gamma mutation in lung cancer disrupts the p53-dependent tumor-suppressor function of protein phosphatase 2A." in: Oncogene, Vol. 29, Issue 27, pp. 3933-41, (2010) (PubMed).
: "Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation." in: Nature cell biology, Vol. 12, Issue 7, pp. 719-27, (2010) (PubMed).
: "Dynamics of cohesin proteins REC8, STAG3, SMC1 beta and SMC3 are consistent with a role in sister chromatid cohesion during meiosis in human oocytes." in: Human reproduction (Oxford, England), Vol. 25, Issue 9, pp. 2316-27, (2010) (PubMed).
: "Visualizing histone modifications in living cells: spatiotemporal dynamics of H3 phosphorylation during interphase." in: The Journal of cell biology, Vol. 187, Issue 6, pp. 781-90, (2009) (PubMed).
: "Heterochromatin links to centromeric protection by recruiting shugoshin." in: Nature, Vol. 455, Issue 7210, pp. 251-5, (2008) (PubMed).
: "Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis." in: Cell research, Vol. 17, Issue 7, pp. 608-18, (2007) (PubMed).
: "Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity." in: The Journal of cell biology, Vol. 178, Issue 3, pp. 345-54, (2007) (PubMed).
Synonyme und alternative Namen zu Shugoshin
shugoshin 1 (Sgo1), shugoshin centromeric cohesion 1 (sgo1), shugoshin 1 L homeolog (sgo1.L), shugoshin 1 (SGO1), 3300001M08Rik, C81037, NY-BR-85, SGO, sgo1, Sgo1Bezeichner auf Proteinebene für Shugoshin
- AY109536_SNP
- CL5684_1
- CL5684_1_ov
- gnp_AW055587
- gpm134
- p-std614083G09
- shugoshin-1
- shugoshin-like protein
- shugosin centromeric cohesion1
- std614083G09
- zmSGO1
- xsgo
- hSgo1
- serologically defined breast cancer antigen NY-BR-85
- shugoshin 1AB protein
- shugoshin 1CD protein
- shugoshin 1EF protein
- shugoshin 1GH protein
- shugoshin 1KL protein
- shugoshin-like 1
- shugoshin 1A protein
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