Maus anti-Human Immunoglobulin kappa Chain Complex (Igk) (Light Chain) Antikörper (CF®488A)

Produktnummer ABIN7879479

Kurzübersicht für Maus anti-Human Immunoglobulin kappa Chain Complex (Igk) (Light Chain) Antikörper (CF®488A) (ABIN7879479)

Target: Igk (Immunoglobulin kappa Chain Complex (Igk))

Klonalität: Monoklonal

Konjugat: CF®488A

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: KLC709

Isotyp: IgG1, kappa

Produktdetails

Bindungsspezifität: Light Chain

Reaktivität: Human

Wirt: Maus

Verwendungszweck: Kappa Light Chain Antibody

Aufreinigung: Protein G affinity chromatography

Immunogen: Recombinant human Kappa light chain was used as the immunogen for this Kappa light chain antibody.

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Kappa Light Chain antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 500 µL at 0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the Kappa Light Chain antibody at 2-8oC, protected from light.

Antigendetails

Target: Igk (Immunoglobulin kappa Chain Complex (Igk))

Andere Bezeichnung: Kappa

Hintergrund: This antibody is specific to the kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. In general, the ratio of Kappa to Lambda is 3:1. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.