Rekombinanter Maus anti-Human Immunoglobulin kappa Chain Complex (Igk) (Light Chain) Antikörper

Produktnummer ABIN7879475

Kurzübersicht für Rekombinanter Maus anti-Human Immunoglobulin kappa Chain Complex (Igk) (Light Chain) Antikörper (ABIN7879475)

Target: Igk (Immunoglobulin kappa Chain Complex (Igk))

Antikörpertyp: Recombinant Antibody

Klonalität: Monoklonal

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: RL1C1

Isotyp: IgG1, kappa

Produktdetails

Bindungsspezifität: Light Chain

Reaktivität: Human

Wirt: Maus

Verwendungszweck: Recombinant Kappa Light Chain Antibody (azide and preservative free)

Aufreinigung: Protein G affinity chromatography

Immunogen: Recombinant human Ig kappa chain was used as the immunogen for this recombinant Kappa Light Chain antibody.

Anwendungsinformationen

Applikationshinweise: The optimal dilution of the recombinant Kappa Light Chain antibody for each application should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the recombinant Kappa Light Chain antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Antigendetails

Target: Igk (Immunoglobulin kappa Chain Complex (Igk))

Andere Bezeichnung: Kappa

Hintergrund: This mAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

UniProt: P01601