SETD7 Produkte
(SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))
Kategorien
Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation.
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Ausgewählte SETD7 Kategorien
SETD7 Antikörper
High quality antibodies with extensive validation data.
SETD7 ELISA Kits
Reliable ELISA kits for a wide range of species.
SETD7 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene SETD7 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Monkey, Rat
Applikation
WB, ELISA, IHC
Validierungen
- (5)
Kat. Nr.
ABIN7193393
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Monkey, Rat
Applikation
WB, ELISA, FACS
Validierungen
- (5)
Kat. Nr.
ABIN7193392
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF, IHC (p)
Validierungen
- (5)
Kat. Nr.
ABIN566461
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene SETD7 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6959453
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6951695
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene SETD7 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7564766
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7555491
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7504524
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren SETD7 Produkten
: "Minimally invasive implantation and decreased inflammation reduce osteoinduction of biomaterial." in: Theranostics, Vol. 10, Issue 8, pp. 3533-3545, (2021) (PubMed).: "Setd7 and its contribution to Boron-induced bone regeneration in Boron-mesoporous bioactive glass scaffolds." in: Acta biomaterialia, Vol. 73, pp. 522-530, (2018) (PubMed).
: "SET9-Mediated Regulation of TGF-β Signaling Links Protein Methylation to Pulmonary Fibrosis." in: Cell reports, Vol. 15, Issue 12, pp. 2733-44, (2016) (PubMed).
: "Regulation of estrogen receptor alpha by the SET7 lysine methyltransferase." in: Molecular cell, Vol. 30, Issue 3, pp. 336-47, (2008) (PubMed).
: "Protein demethylation required for DNA methylation." in: Nature genetics, Vol. 41, Issue 1, pp. 10-1, (2008) (PubMed).
: "The coactivator host cell factor-1 mediates Set1 and MLL1 H3K4 trimethylation at herpesvirus immediate early promoters for initiation of infection." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 26, pp. 10835-40, (2007) (PubMed).
: "Regulation of p53 activity through lysine methylation." in: Nature, Vol. 432, Issue 7015, pp. 353-60, (2004) (PubMed).
: "Mechanism of histone lysine methyl transfer revealed by the structure of SET7/9-AdoMet." in: The EMBO journal, Vol. 22, Issue 2, pp. 292-303, (2003) (PubMed).
: "Structure and catalytic mechanism of the human histone methyltransferase SET7/9." in: Nature, Vol. 421, Issue 6923, pp. 652-6, (2003) (PubMed).
: "Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1." in: Genes & development, Vol. 17, Issue 7, pp. 896-911, (2003) (PubMed).
Synonyme und alternative Namen zu SETD7
SET domain containing lysine methyltransferase 7 (SETD7), SET domain containing (lysine methyltransferase) 7 (setd7), SET domain containing (lysine methyltransferase) 7 (Setd7), 1600028F23Rik, H3K4MT, KMT7, mKIAA1717, SET7, set7, Set7, SET7/9, Set7/9, SET9, zgc:92330, zgc:101860Bezeichner auf Proteinebene für SETD7
- H3-K4-HMTase SETD7
- SET domain-containing protein 7
- histone H3-K4 methyltransferase SETD7
- histone H3-lysine 4-specific methyltransferase
- histone-lysine N-methyltransferase SETD7
- lysine N-methyltransferase 7
- H3-K4 methyltransferase
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