Protein Überblick

The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3).

Alternative names and synonyms associated with Fibulin 5 (FBLN5)

• fibulin 5 (fbln5) Antikörper
• fibulin 5 (FBLN5) Antikörper
• fibulin 5 (Fbln5) Antikörper

• A55 Antikörper
• ADCL2 Antikörper
• ARCL1A Antikörper
• ARMD3 Antikörper
• DANCE Antikörper
• Alle Synonyme
• DKFZp469K0327 Antikörper
• EVEC Antikörper
• FBLN5 Antikörper
• FIBL-5 Antikörper
• Fibulin-5 Antikörper
• MGC108414 Antikörper
• UP50 Antikörper
• zgc:103575 Antikörper

Bezeichner auf Proteinebene für anti-Fibulin 5 (FBLN5) Antikörper

fibulin-5 , fibulin 5 , fibulin-5-like , developmental arteries and neural crest EGF-like protein , urine p50 protein , FIBL-5 , EVEC , dance , embryonic vascular EGF repeat-containing protein