Fibulin 5 Antikörper (AA 199-448)

Produktnummer ABIN6140497

Produktdetails anti-Fibulin 5 Antikörper

Target: Fibulin 5 (FBLN5)

Bindungsspezifität: AA 199-448

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Fibulin 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: NEDGRSCQDV NECATENPCV QTCVNTYGSF ICRCDPGYEL EEDGVHCSDM DECSFSEFLC QHECVNQPGT YFCSCPPGYI LLDDNRSCQD INECEHRNHT CNLQQTCYNL QGGFKCIDPI RCEEPYLRIS DNRCMCPAEN PGCRDQPFTI LYRDMDVVSG RSVPADIFQM QATTRYPGAY YIFQIKSGNE GREFYMRQTG PISATLVMTR PIKGPREIQL DLEMITVNTV INFRGSSVIR LRIYVSQYPF

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 199-448 of human FBLN5 (NP_006320.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:100

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Fibulin 5

Target: Fibulin 5 (FBLN5)

Andere Bezeichnung: FBLN5 (FBLN5 Produkte)

Synonyme: zgc:103575 antikoerper, FBLN5 antikoerper, MGC108414 antikoerper, Fibulin-5 antikoerper, DKFZp469K0327 antikoerper, ADCL2 antikoerper, ARCL1A antikoerper, ARMD3 antikoerper, DANCE antikoerper, EVEC antikoerper, FIBL-5 antikoerper, UP50 antikoerper, A55 antikoerper, fibulin 5 antikoerper, fbln5 antikoerper, FBLN5 antikoerper, Fbln5 antikoerper

Hintergrund: The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3).,FBLN5,ADCL2,ARCL1A,ARMD3,DANCE,EVEC,FIBL-5,HNARMD,UP50,fibulin-5,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cell Adhesion Molecules,Cytoskeleton,Extracellular Matrix,Cardiovascular,Cardiovascular diseases,Hypertension,FBLN5

Molekulargewicht: 50 kDa

Gen-ID: 10516

UniProt: Q9UBX5

Pathways: SARS-CoV-2 Protein Interaktom